Can acetylsalicylic acid cause allergies?

Among the many types of negative reactions to medications, an allergy to aspirin deserves special attention. The exact causes of this pathology have not yet been clarified. With the help of this drug it is easy to get rid of pain, it relieves fever and inflammation. However, this well-known medicine is not as safe as many people think: quite often patients experience hypersensitivity to acetylsalicylic acid, and taking the drug leads to the development of an allergic reaction, sometimes in a severe form.

"Aspirin": composition of tablets

The main active ingredient of the drug is acetylsalicylic acid, which determines the pharmacological effect of this drug. In addition, Aspirin contains substances that give the tablet its appearance and shape: cellulose and starch. They do not affect the effect of the drug.

Aspirin Cardio contains an enteric coating that prevents the tablet from dissolving in the stomach, which reduces the likelihood of ulcers. Substances that give the drug special properties - sodium bicarbonate and citric acid are included in the effervescent forms of aspirin.

Reasons for the reaction

Some patients ask the rhetorical question “Where does an allergy to aspirin come from?” The nature of this reaction has not yet been precisely identified. It is assumed that the appearance of intolerance is not due to an independent reaction, but to other chronic allergic diseases. Research confirms that it occurs more often in women.

If you are predisposed to allergies, acetylsalicylic acid entering the body causes the appearance of antibodies that combine with antigens and the process develops. Mast cells, which contain biologically active allergy substances, are activated. Hypersensitization develops and upon repeated contact it causes the appearance of symptoms.

Prevention of disease occurrence

Allergy to aspirin is one of the most common diseases. For the first time, symptoms of the disease may appear at age 30. They occur much more often in women than in men. In children, such a reaction is rare. Today, the mechanism of the appearance of the symptoms of the disease has not been fully studied and scientists have not yet been able to determine what causes the allergic reaction.

However, there is an observation that in people prone to allergic reactions, when taking aspirin, the metabolism of arachidonic acid occurs. Other experts believe that an allergy to aspirin may be due to the effect of acetylsalicylic acid on the body's mast cells. In addition, it has been found that when taking aspirin and alcohol simultaneously, a specific reaction occurs, which can provoke the development of an allergic reaction, and in some cases, gastric bleeding.

Symptoms: itching, peeling.

As a preventative measure, you should take medications very carefully and avoid those that contain acetylsalicylic acid. It is also necessary to avoid taking other medications that can provoke an allergic reaction. It is very important to adhere to some diet. All foods that can cause allergies should be excluded from the diet.

In addition, it is necessary to provide the body with vitamins and minerals that can support the human immune system. However, before you start taking a vitamin complex, you should consult an allergist, and it is best to undergo additional tests for a possible allergic reaction. This will keep the patient safe and protect him from further unpleasant symptoms.

Mild to moderate symptoms

The first signs of allergy appear in respiratory disorders:

  • nasal congestion;
  • the formation of polyps that make breathing difficult;
  • the appearance of liquid secretion;
  • impaired sense of smell.

Additional symptoms may include dizziness, headache, decreased performance, and weakness. The mild and moderate group of symptoms include: rash in the form of hives, nausea, vomiting, heartburn.

In the middle stage of an allergy to aspirin, a dry cough and difficulty breathing are added to the listed symptoms. Purulent inflammation develops in the sinuses. Breathing becomes wheezing.

Signs of severe complications

If you do not pay attention to the appearance of the first symptoms of the disease, they begin to resemble attacks of bronchial asthma. This is the most common type of aspirin allergy. The most severe condition is anaphylactic shock, which is characterized by a rapid onset and rapid increase in symptoms. After taking the drug, a person experiences weakness, malaise, and dizziness. Then breathing becomes impaired and he loses consciousness.

The main sign of deterioration is a sharp decrease in blood pressure.

Diet

The nature of the diet in case of an allergy to aspirin is of great importance, since almost all products contain acetylsalicylic acid, and if they are consumed during the period of illness, the condition may worsen and the symptoms of the pathology may worsen.
Therefore, you should carefully study the labels on food products, do not take anything that contains dyes, especially yellowish and orange colors, preservatives, sodium benzoate, flavor enhancers, sulfates, various additives, nitrates, gelatin, etc. It should also be noted that salicylates or salicylic acid esters, which also need to be avoided, are found in some berries, vegetables and fruits, stabilizers and artificial preservatives.

Dietary restrictions are an essential part of the healing measures prescribed by the doctor, and without a diet there will be no healing effect.

You should also stop using mint toothpastes, teeth cleaning powders, and mouth fresheners. Under no circumstances should you take pharmaceuticals such as Naproxen, Alka-Seltzer, Ecotrin, Kaopectate, etc. It is important to pay attention to the fact that aspirin pills may be sold under a different trade name.

Diagnosis of the disease

After detecting the first symptoms of an allergy to aspirin, it is necessary to determine which allergens caused it. An allergist prescribes a provocative test - a dosed dose of aspirin, which in case of allergies exhibits characteristic symptoms.

In addition, a skin test is prescribed. To do this, patients are given a placebo for two days, and aspirin on the third. After this, doctors examine the patient every two hours, recording the absence or appearance of local and general signs.

Often, in the diagnosis of intolerance, an analysis is prescribed to determine immunoglobulins E. Its result will be uninformative in the case of a reaction to aspirin.

First aid at home

To alleviate the patient’s condition caused by taking acetylsalicylic acid, the following rules must be followed:

  • If allergy symptoms appear, take a cool shower.
  • Take adsorbent – ​​“Smecta”, “Enterosgel”, “Filtrum”, activated carbon.
  • Wear clothes made of cotton fabric.
  • Antihistamine or anti-inflammatory creams - Bepanten, Skin-Cap, Protopic - will help relieve skin itching.
  • Only after this can you take antihistamines - Tavegil, Suprastin, Diazolin, Zyrtek.
  • In case of complicated breathing, inhalations are given (Theophedrine, Salbutamol) or taken orally with Eufillin or Broncholitin.
  • To relieve dizziness, you should use the following technique: lying on a hard, flat surface, raise your legs above your head to ensure blood flow. This will saturate the brain cells with oxygen.
  • A hypoallergenic diet is followed for at least 4 days.

Allergy to aspirin: symptoms, what to replace the drug with? Contraindications for prescribing aspirin

Among the many types of negative reactions to medications, an allergy to aspirin deserves special attention. The exact causes of this pathology have not yet been clarified.

With the help of this drug it is easy to get rid of pain, it relieves fever and inflammation.

However, this well-known medicine is not as safe as many people think: quite often patients experience hypersensitivity to acetylsalicylic acid, and taking the drug leads to the development of an allergic reaction, sometimes in a severe form.

What is aspirin?

In accordance with the pharmacological classification, aspirin is included in the group of non-steroidal anti-inflammatory drugs (NSAIDs). This gives it a wide spectrum of action - from pain relief to the prevention of cardiovascular diseases.

“Aspirin”: composition of tablets

The main active ingredient of the drug is acetylsalicylic acid, which determines the pharmacological effect of this drug. In addition, Aspirin contains substances that give the tablet its appearance and shape: cellulose and starch. They do not affect the effect of the drug.

Aspirin Cardio contains an enteric coating that prevents the tablet from dissolving in the stomach, which reduces the likelihood of ulcers. Substances that give the drug special properties - sodium bicarbonate and citric acid are included in the effervescent forms of aspirin.

Some patients ask the rhetorical question “Where does an allergy to aspirin come from?” The nature of this reaction has not yet been precisely identified. It is assumed that the appearance of intolerance is not due to an independent reaction, but to other chronic allergic diseases. Research confirms that it occurs more often in women.

If you are predisposed to allergies, acetylsalicylic acid entering the body causes the appearance of antibodies that combine with antigens and the process develops. Mast cells, which contain biologically active allergy substances, are activated. Hypersensitization develops and upon repeated contact it causes the appearance of symptoms.

Risk factors

This is a widely used drug throughout the world - aspirin. An allergy to a medicine in an adult occurs in 0.04% of the population of our planet. Signs of this type of allergy most often appear in people who suffer from the following diseases:

  • chronic urticaria;
  • bronchial asthma;
  • nasal polyposis;
  • arthritis;
  • allergic rhinitis;
  • dermatitis;
  • blood diseases.

Symptoms of the disease

Manifestations of aspirin allergy most often affect the respiratory system. They manifest themselves to varying degrees, depending on the amount of the drug and the strength of the allergen.

The first signs of allergy appear in respiratory disorders:

  • nasal congestion;
  • the formation of polyps that make breathing difficult;
  • the appearance of liquid secretion;
  • impaired sense of smell.

Additional symptoms may include dizziness, headache, decreased performance, and weakness. The mild and moderate group of symptoms include: rash in the form of hives, nausea, vomiting, heartburn.

In the middle stage of an allergy to aspirin, a dry cough and difficulty breathing are added to the listed symptoms. Purulent inflammation develops in the sinuses. Breathing becomes wheezing.

Signs of severe complications

If you do not pay attention to the appearance of the first symptoms of the disease, they begin to resemble attacks of bronchial asthma. This is the most common type of aspirin allergy.

The most severe condition is anaphylactic shock, which is characterized by a rapid onset and rapid increase in symptoms. After taking the drug, a person experiences weakness, malaise, and dizziness.

Then breathing becomes impaired and he loses consciousness.

The main sign of deterioration is a sharp decrease in blood pressure.

Side effects

Adverse reactions to the drug increase if the dosage and dosage regimen is violated. First of all, this concerns the digestive tract: nausea; stomach ache; bleeding from the gastrointestinal tract.

Diagnosis of the disease

After detecting the first symptoms of an allergy to aspirin, it is necessary to determine which allergens caused it. An allergist prescribes a provocative test - a dosed dose of aspirin, which in case of allergies exhibits characteristic symptoms.

In addition, a skin test is prescribed. To do this, patients are given a placebo for two days, and aspirin on the third. After this, doctors examine the patient every two hours, recording the absence or appearance of local and general signs.

Often, in the diagnosis of intolerance, an analysis is prescribed to determine immunoglobulins E. Its result will be uninformative in the case of a reaction to aspirin.

Treatment

When the cause of the disease is established, the first way to help cope with any intolerance is to eliminate the allergen. It is necessary to exclude drugs containing acetylsalicylic acid and replace them with other drugs prescribed by the doctor.

Desensitization therapy

When replacing Aspirin is impossible (after a myocardial infarction, ischemic stroke), doctors use the desensitization method - a gradual decrease in sensitivity to aspirin.

To do this, a minimum dose of this drug is prescribed and gradually increased. After a short time, sensitivity to acetylsalicylic acid disappears.

To speed up this process, antihistamines are prescribed.

First aid at home

To alleviate the patient’s condition caused by taking acetylsalicylic acid, the following rules must be followed:

  • If allergy symptoms appear, take a cool shower.
  • Take adsorbent – ​​“Smecta”, “Enterosgel”, “Filtrum”, activated carbon.
  • Wear clothes made of cotton fabric.
  • Antihistamine or anti-inflammatory creams - Bepanten, Skin-Cap, Protopic - will help relieve skin itching.
  • Only after this can you take antihistamines - Tavegil, Suprastin, Diazolin, Zyrtek.
  • In case of complicated breathing, inhalations are given (Theophedrine, Salbutamol) or taken orally with Eufillin or Broncholitin.
  • To relieve dizziness, you should use the following technique: lying on a hard, flat surface, raise your legs above your head to ensure blood flow. This will saturate the brain cells with oxygen.
  • A hypoallergenic diet is followed for at least 4 days.

Providing assistance for severe symptoms

If, after the appearance of an allergy symptom, a person’s condition sharply worsens, then emergency help is required. To do this, antihistamines are administered intravenously and hormonal drugs are prescribed in high dosages.

If you are allergic to aspirin, what can you replace this drug with? You can use drugs from two different groups: anticoagulants and antithrombotics. If there is a threat of clot formation, then drugs based on another active ingredient are used - Clopidogrel, Curantil. Blood is thinned by Heparin and Warfarin.

Cheap allergy pills

It is no secret that new IV generation antihistamines are very effective, but are quite expensive. Many allergy sufferers are interested in whether there are cheap allergy pills? Yes, there are such drugs. These include:

  • "Loratadine" - 10 tablets 40 rubles.
  • "Aleron" - 10 pieces 78 rubles.
  • "Diazolin" - 10 pieces 80 rubles.
  • "Claridol" - 7 pieces 95 rubles.

Contraindications to the drug

Contraindications for prescribing aspirin are:

  1. Gastrointestinal ulcers.
  2. Asthma.
  3. Diathesis.
  4. Low platelet count.
  5. Hemophilia.
  6. Kidney and liver failure.
  7. Breast-feeding.
  8. Age up to three years.

Prevention Tips

To avoid severe symptoms of an allergy to aspirin, remove the drug from your medicine cabinet and replace it with a similar product with a different active ingredient. It is prescribed by a doctor, taking into account all contraindications.

Source: https://FB.ru/article/400652/allergiya-na-aspirin-simptomyi-chem-zamenit-preparat-protivopokazaniya-dlya-naznacheniya-aspirina

Allergy to Aspirin

Among the numerous allergic manifestations associated with taking medications, allergy to Aspirin (acetylsalicylic acid) stands apart, since doctors have still not been able to determine the true causes of this disease, which affects 0.44% of the world's inhabitants.

The term “aspirin triad” is inextricably linked with the concept of allergy to Aspirin.

It is also worth noting that this pathology is more common in adults, since doctors do not recommend aspirin for children at all, since this risks destroying the gastric mucosa of the child’s still fragile body.

  • involuntary belching, nausea or vomiting;
  • thirst, the appearance of a bitter taste;
  • pain in the pit of the stomach (epigastric region);
  • changes in the color and quality of stool.

An allergy to Aspirin may also be accompanied by dizziness, extraneous sounds in one or both ears, lethargy, loss of orientation in time and space, and migraine.

Such signs already indicate damage to the nervous system of a toxic nature. In addition, allergies cause pressure surges, a feeling of unmotivated fatigue, and a decrease in body temperature.

This disease is often accompanied by scabies, red spotty rashes, hives, swelling, and numbness in the back of the head.

Diagnostic features

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Predisposing factors

In most cases, aspirin allergy occurs in predisposed individuals. Some diseases can serve as a background for the development of a pathological reaction:

  • polyposis of the nasal passages and sinuses,
  • bronchial asthma,
  • allergic rhinitis, conjunctivitis, dermatitis,
  • hay fever

In the presence of the above diseases, the risk of developing an allergic reaction when prescribing the drug increases many times. Treating an allergy to aspirin is difficult. To get rid of the disease, you need to find out its exact cause. Chronic diseases or individual hypersensitivity to the components of the drug can cause a pathological reaction to the drug.

Particular caution when taking acetylsalicylic acid should be observed by all asthma sufferers - the use of this substance can not only provoke an exacerbation of the process, but also negatively affect the course of the disease as a whole.

How to identify an allergen?

After detecting symptoms, it is necessary to determine which allergens caused the intolerance. For this, a provocative test is prescribed. This is a dosed dose of aspirin, which in case of allergies will show symptoms.

In addition to the provocative oral test, a skin test is prescribed. To do this, patients are given a placebo for the first 2 days, and the drug on the 3rd day. Then, every 2 hours, the staff examines the patient, recording the appearance or absence of local and general signs of allergy.

In the diagnosis of intolerance, an analysis is often prescribed to determine immunoglobulins E. If you react to aspirin, the result will be uninformative.

Allergy symptoms

The most common respiratory symptoms are:

  • an asthma attack that occurs after taking the drug;
  • wheezing that can be heard even at a distance;
  • a feeling of constriction in the lungs, the inability to take a full breath;
  • severe shortness of breath.

In case of individual intolerance to aspirin, pathological symptoms also appear in the digestive system:

  • A bitter taste appears in the mouth, thirst.
  • Nausea and belching are common.
  • There is pain in the epigastric region.
  • The nature and color of stool changes.

When taking aspirin, dizziness, loss of orientation in space, apathy, migraines and tinnitus may occur - all this indicates toxic damage to the nervous system.

An allergic reaction is accompanied by a feeling of unmotivated fatigue, an increase or decrease in blood pressure and a decrease in body temperature. Skin changes may appear - a red spotty rash on the body, accompanied by itching, hives, swelling. In some cases, there is numbness in the back of the head.

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