Ruzam allergy medicine instructions for use, price, reviews

General information about the drug

Ruzam is a medicinal aqueous solution for subcutaneous injection, which is a clear liquid with a faint odor of phenol.

The main component in Ruzam is an extract from cultures of heat-resistant strains of Staphylococcus aureus. The product also contains auxiliary components such as sodium chloride and phenol.

The medicine Ruzam is sold in the Russian pharmacy chain in cardboard packages, each of which contains five ampoules of the drug with a volume of 0.2 milliliters.

Impact on the body

Ruzam has a pronounced anti-inflammatory and anti-allergic effect. It also allows you to significantly reduce swelling of the skin and mucous membrane while simultaneously reducing the concentration of eosinophils and degranulated cells at the site of the inflammatory process. In addition, Ruzam stimulates the production of secretory immunoglobulin A in the mucosa, which increases its resistance to the effects of pathogenic microflora. Ruzam makes it possible to reduce the concentration of the main inflammatory allergic markers, which generally improves the general condition of a person after contact with allergens.

Patients taking this medication have clinically demonstrated a decrease in allergic markers, indicating the overall effectiveness of the drug. At the same time, the level of immunoglobulin E decreases in the patient’s blood, while the concentration of nitric oxide in the person’s exhaled air decreases.

Packaging, composition and release form of the medicinal product

In what form is the medicine “Ruzam” sold? The instructions indicate that this product is available in the form of a solution intended for subcutaneous injection. It contains an extract made from a culture of a thermophilic strain of Staphylococcus aureus. The medicine also contains a 0.9% solution of sodium chloride and 0.03–0.05% phenol.

The drug "Ruzam" is sold in ampoules, which are contained in blister packs of five pieces in a pack of thick paper.

Do you know what the drug “Ruzam” is? The instructions state that this is an antiallergic and anti-inflammatory drug. According to experts, it can reduce swelling of the skin and mucous membranes, as well as increase the level of secretory IG (immunoglobulin) class A in the mucous membranes and help reduce the number of mast cells (degranulated) and eosinophils in the inflamed area. In addition, the drug in question reduces the level of markers of allergic inflammation and eliminates the severity of adverse reactions.

When should subcutaneous injections with “Ruzam” be given? According to the instructions, this drug is most effective for:

hives;
allergic rhinitis;
bronchial asthma;
allergic dermatitis;
angioedema;
respiratory infections (frequent).

Under what conditions of the patient is it not recommended to use the drug “Ruzam”? The instructions indicate that this drug should not be prescribed if the patient has a negative reaction to the substances of the drug. Also, injections cannot be given during breastfeeding, during gestation, during acute infection, active tuberculosis and decompensated diseases of internal organs.

It should also be noted that the drug in question is contraindicated in children under 4 years of age.

Indications and contraindications for taking the drug

The main clinical indications for the use of this drug include:

chronic rhinitis of an allergic nature;
various forms of bronchial asthma;
development of urticaria;
the occurrence of Quincke's edema;
dermatitis of allergic and non-allergic origin;
chronic respiratory infections.

The main contraindications for the use of Ruzam are as follows:

individual high sensitivity to individual components included in the drug;
development of acute infectious diseases within the body;
active form of tuberculosis;
diseases of internal organs of a decompression nature;
pregnancy and breastfeeding;
under four years of age.

Indications for use of Ruzam

The drug Ruzam must be prescribed by an allergist. The list of diseases for which Ruzam is effective includes:

Allergic year-round or seasonal rhinitis;
Bronchial asthma;
Urticaria;
Dermatitis of allergic origin;
Angioedema;
Frequently recurring respiratory infections.

Ruzam can be prescribed regardless of the total duration of the disease. It is only necessary to take into account that a greater effect will be achieved if allergy treatment is started at the first symptoms of this disease.

Instructions for use of Ruzam for allergies for adults and children

How to take this medicine is described in detail in the instructions for the drug. Children aged 4 to 6 years are often prescribed a course of Ruzam as an injection once a week at a dosage of 0.1 milliliter. For children over 6 years of age and adult patients, Ruza is prescribed in a dosage of 0.2 milliliters once a week. In both cases, the course of taking the drug is from 5 to 10 weeks. Over the course of a calendar year, up to four treatment courses are allowed.

In case of hay fever in a patient, the use of this medicine is prescribed 1.5-2 months before the start of the period of active flowering of plants. In the presence of chronic respiratory diseases, the drug is used as a preventive measure in autumn and spring.

As for the use of Ruzam by pregnant women, as well as breastfeeding mothers, its use by such patients is not recommended.

Ruza is not prescribed for children under 4 years of age.

Injection solution "Ruzam": instructions for use

How should this medication be used? It should only be prescribed by a doctor, based on medical examination data. By the way, it is the doctor who determines the required dosage of the drug and the duration of treatment.

According to the instructions, the drug in question should be administered only subcutaneously. For children over 6 years of age, injections are given at 0.2 ml. For children aged 4-6 years, a dose of 0.1 ml is indicated.

The solution is administered to the patient once a week. Therapy with this drug should continue for 1-2.5 months. There can be from 1 to 4 such courses per year. The interval between them should be about 20 days.

When hay fever develops, injections are prescribed 6-8 weeks before the first flowering of plants that cause an allergic reaction. For preventive measures against frequent respiratory infections, the medication is recommended to be used in autumn and spring.

Is it possible to increase the dose of Ruzam? Reviews report that in case of urgent need, the dosage of this medication can be increased to 0.3 ml (administered every 5 days).

What negative reactions may occur while using the drug "Ruzam"? Consumer reviews say that this product often causes undesirable effects. For example, some patients develop weakness, malaise, worsening cough, low-grade fever, or rash. As a rule, all of these symptoms are mild. Moreover, they go away on their own and do not require discontinuation of the medication.

No drug interactions of the drug “Ruzam” with other medications have been registered. According to most doctors, this medicine can be used together with antibiotics, glucocorticosteroids and antihistamines.

What should you know before using Ruzam? Reviews from doctors report that this product does not have any effect on human work associated with potentially dangerous mechanisms that require quick reaction and special attention (for example, driving a vehicle, etc.).

It should also be noted that the solution remaining in the ampoule cannot be used for the next injection. It must be disposed of.

The medicine in question is sold in pharmacies only with a doctor's prescription. The medication should be kept in a dark place inaccessible to small children. In this case, the storage temperature of the drug in ampoules is 4-20 degrees.

The shelf life of this product is four years. It is strictly forbidden to use ampoules with the drug after the specified period.

The drug "Ruzam" is considered a unique remedy. Therefore, this medication has no structural analogues.

According to consumers, the price of this medicine is quite high. Its cost is about 1600 rubles.

Reviews from specialists and consumers about the drug “Ruzam” can be found very different. However, most of them are positive. Patients using this product claim that it quickly helped them cope with allergies. However, some people note that undesirable reactions still occur during the flowering period of plants, although without serious consequences.

As for doctors, they believe that this is the most effective and unique drug in its properties, the quality of which fully corresponds to the price.

For the treatment of chronic allergies, a course of antihistamine tablets is usually prescribed; drug injections are rarely used.

An exception may be the drug Ruzam; following the schedule of its administration helps get rid of certain types of allergies and also prevents the development of a number of allergic reactions.

How does an overdose manifest and what side effects may occur?

Clinical studies have not established the amount of drug at which an overdose may occur. However, in case of individual intolerance to certain components of Ruzam, you should immediately consult a doctor and take an antihistamine.

When using this medicine, the following adverse reactions are observed in some cases:

a sharp increase in body temperature, accompanied by chills and headache;
the appearance of general muscle weakness;
exacerbation of infectious diseases and pathologies;
increased cough with short-term bronchitis;
increased skin rashes of allergic origin.

All such symptoms are most often mild in nature, which allows them to quickly pass on their own without the need to stop taking Ruzam.

The drug has an official website, which has a feedback form that must be filled out in case of side effects.

Clinical and pharmacological group and composition of the drug Ruzam

Ruzam belongs to the group of drugs with antiallergic effects. The main active ingredient of this medication is an extract obtained from a thermophilic strain of Staphylococcus aureus.

In addition to the drug, phenol and an injection solution, that is, 0.9% sodium chloride, were added in a minimal amount.

Ruzam is available only in ampoules with a dosage of 0.2 or 0.5 ml. The solution in ampoules is colorless or slightly colored.

Ruzam is used as an antiallergic and anti-inflammatory medicine.

After injection of the drug, the following changes are observed:

Swelling of the skin and mucous membranes of the nasopharynx and respiratory system organs is reduced.
At the site of inflammation, the number of eosinophils decreases and the process of degranulation of mast cells is blocked.
The percentage of secretory immunoglobulin from class A in the mucous layers increases, and this increases their protection against infectious agents.
The content of total immunoglobulin from class E, which is a marker of an allergic reaction, decreases in the blood.
The amount of nitric oxide in the exhaled air decreases.

When treated with Ruzam, the severity of allergy symptoms decreases, and some manifestations inherent in this disease disappear completely.

The drug Ruzam must be prescribed by an allergist. The list of diseases for which Ruzam is effective includes:

Allergic year-round or seasonal rhinitis;
Bronchial asthma;
Urticaria;
Dermatitis of allergic origin;
Angioedema;
Frequently recurring respiratory infections.

The main contraindications to the administration of Ruzam are mostly temporary.

Treatment with this drug is delayed:

Throughout pregnancy and during breastfeeding.
For active tuberculosis.
Children up to 4 years old.
Acute infectious diseases. After respiratory infections, the course of treatment with Ruzam is usually postponed for about a month.

Absolute contraindications include individual intolerance to the medication and decompensated pathologies of internal organs.

It must be taken into account that adverse reactions may occur throughout treatment with Ruzam. The most common of them include:

General malaise, weakness and lethargy.
Periodic increase in body temperature to subfebrile levels.
Worsening coughing attacks or worsening skin rashes.

Typically, all side effects are mild and disappear completely upon completion of the course of treatment.

Special instructions for use

To date, the interaction of Ruzam with other pharmacological agents has not been clinically established. This medicine may be prescribed together with various antihistamines, antibiotics or glucocorticosteroids.

Also, the drug does not affect a person’s concentration in any way, which allows vehicle drivers to take it freely and operate various complex mechanisms.

However, doctors do not recommend drinking alcohol while using Ruzam, as this can lead to increased side effects.

If you have impaired renal or liver function, the use of this drug should be under the close supervision of a physician with regular testing.

Evaluation of doctors and patients

Reviews from doctors and patients about the allergy drug Ruzam are mostly good. Its high efficiency is noted.

My medical practice, which is more than 15 years, has shown that Ruzam is able to significantly reduce the manifestations of seasonal allergies. Many patients note significant relief from the second week of the course. At the same time, those people who have individual sensitivity to its individual components should approach the use of this product with caution.

Alexey Ivchenkov, allergist

For me, the main advantage of Ruzam is that this drug is a non-hormonal drug with a pronounced effect. With his help I got rid of my atopic dermatitis. The course of treatment lasted two months, during which I went to the clinic for an injection once a week. To achieve the full effect of the cure, I had to undergo three two-month courses of treatment with this drug, after which I felt real relief from getting rid of my problem. Now my skin has regained its healthy appearance and I am no longer bothered by constant itching. Of course, my disease is recurrent, so it is impossible to cure it completely, but thanks to Ruzam, I have been in stable remission for almost three years. Maria, 45 years old

I have suffered from allergies since childhood. After I unsuccessfully tried a bunch of different medications while self-medicating, I finally decided to go to an allergist. The doctor prescribed me an appointment with Ruzam. At first, I really began to notice some improvement in my condition. When I repeated the course, I no longer observed any particular positive effect. The same can be said about the third one. For this reason, I had to stop using Ruzam due to the fact that this drug works extremely poorly for me.

Victoria, 25 years old

According to patient observations, taking Ruzam does not make contact with plant pollen safe. For this reason, you should be very careful during the period of active flowering of plants and keep traditional antihistamines with you. It is also important to be under close medical supervision when taking a course of Ruzam in case of chronic inflammatory kidney diseases, since sometimes patients note a deterioration in the condition of these organs.

The main advantage of this drug is its effectiveness with rare injections. Also, its advantages often include the fact that it is not a hormonal agent.

As for the disadvantages of Ruzam, they include a fairly extensive list of side effects, although they appear quite rarely. Often, while taking this drug, there is an increase in body temperature and, as a result, chills, accompanied by a headache. Also, many are not satisfied with the relatively high cost of this drug in comparison with other antiallergic pharmacological agents.

Features of use and dosage of the drug Ruzam

The medicine Ruzam should be administered only subcutaneously, usually this is done in the upper third of the shoulder from the outside. The drug is practically painless when administered.

The dosage is selected depending on age:

When treating children aged 4 to 6 years, a single dose should not exceed 0.1 ml.
For children over six years of age and all other patients, Ruza is administered in a volume of 0.2 ml.

Injection administration of the medication is usually prescribed once a week. The entire course lasts a minimum of 5 weeks, a maximum of 10 weeks.

Over the course of a year, a doctor can prescribe up to 4 courses of treatment with Ruzam, but the interval between them should not be less than 20 days.

For hay fever, injections should be prescribed approximately two months before a plant species that is allergenic to humans begins to bloom.

If Ruzam is used as an immunomodulatory agent for respiratory infections, then it is recommended to administer it in courses in the spring and autumn.

For severe allergic reactions, the dosage can be increased to 0.3 ml, and the frequency of administration reduced to once every five days.

The drug Ruzam can be purchased at pharmacy chains by presenting a prescription from a doctor. There are certain requirements for storing medicine.

Ruza must be stored only at temperatures between 4 and 20 degrees, that is, in the refrigerator.

The temperature regime must also be observed during transportation of the drug.

Failure to comply with storage conditions leads to a decrease in the therapeutic effect and increases the risk of allergic reactions.

If all storage conditions are met, then Ruzam perfectly retains all its properties for four years from the date of its release.

At the moment, Ruzam is considered a drug with a unique mechanism of action, so there are no structural analogues of this medication.

The cost of Ruzam is quite high; a box of five 0.2 ml ampoules costs approximately $25.

Many patients have already experienced the effects of the drug Ruzam, because all people suffering from this disease want to get rid of allergies.

Some of those who underwent treatment were satisfied with the result, others did not identify certain advantages of the medication.

But it’s best to read reviews about it from real people before deciding to buy Ruzam prescribed by a doctor.

Bronchial asthma has been accompanying me for more than 10 years, and attacks become more frequent in the spring.

My pulmonologist advised me to put Ruzam three years ago and now I resort to this remedy every year. I start the course around January and finish it by spring.

Naturally, I cannot completely eliminate all the symptoms of my illness, but I am pleased with the absence of severe suffocation and almost always feel quite good.

Ruzam helped me reduce the symptoms of hay fever. I completed one course, but for the second I couldn’t get the medicine. I was afraid to order online.

Anatoly, 32 years old.

Ruza was discharged from recurrent urticaria. The drug did not help at all and the reason for this is that they incorrectly determined what caused the spots on my body.

A visit to another doctor allowed me to find an effective drug. And I feel so sorry for wasting money on Ruzam.

I took Ruzam on the advice of a friend and thereby provoked the development of certain disorders in my body, so I had to stay in the hospital.

The doctor scolded me, and after the examination she prescribed a completely different drug. Given my illness, Ruzam could only do harm.

Only Ruzam helped me with allergic rhinitis. I experienced attacks of sneezing and nasal congestion in response to dust and various plants.

I’ve been piercing my ruza twice a year for five years, and so far I’m quite happy with the results.

My daughter was prescribed Ruza for bronchial asthma. Honestly, after the first two injections I wanted to refuse, as the cough got worse and the weakness got worse.

But the doctor explained that this happens and advised not to interrupt the treatment.

Three months have passed since we administered the first 10 injections of the drug, and now I want to say that there are positive results, and my daughter’s mood has also improved.

Ruzam specifically did not help me at all with my asthma. But a friend from the hospital allowed me to almost completely get rid of attacks.

Anna Petrovna, 53 years old.

They prescribed Ruzam for contact dermatitis, the drug did not help at all, moreover, all the skin changes only intensified. Now, as before, I save myself with hormonal ointments.

Every spring and almost all summer, my son literally suffered from rhinitis. His cough and nasal congestion did not allow him to play outside for a long time.

A wide variety of drugs were used for treatment, but it became easier only after a course of Ruzam.

At the beginning of next year I want to re-treat the child.

I put one course on Ruzam, and I couldn’t believe how easily I got through this spring and summer. There was virtually no sneezing, no nasal congestion, and no discharge. I am pleased.

To summarize, we can say that Ruzam is a medicine that should not be taken on the recommendation of friends or on one’s own initiative.

The drug should only be prescribed by a doctor, otherwise, at best, you will not get a therapeutic effect and will waste your money. And in the worst case, harm your body.

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Analogs

To date, there are no pharmacological drugs that have a similar composition to Ruzam. For this reason, we can say that this drug has no analogues. If the doctor has prescribed this medication to the patient, but the patient cannot find it in the pharmacy chain, it is necessary to select an allergy medicine with similar properties, but with a different composition and main active ingredient. With a competent approach and taking into account all the specifics of the clinical picture in a particular patient, an experienced doctor will be able to choose the most successful and effective alternative for this medicine.

Terms of sale and storage

The drug Ruzam can be purchased at pharmacy chains by presenting a prescription from a doctor. There are certain requirements for storing medicine.

Ruza must be stored only at temperatures between 4 and 20 degrees, that is, in the refrigerator.

The temperature regime must also be observed during transportation of the drug.

Failure to comply with storage conditions leads to a decrease in the therapeutic effect and increases the risk of allergic reactions.

If all storage conditions are met, then Ruzam perfectly retains all its properties for four years from the date of its release.