Lecrolin eye drops: instructions and dosage

For allergic keratitis and conjunctivitis, Lecrolin eye drops effectively help. This antihistamine pharmaceutical, intended for topical use, has minimal restrictions on use and practically does not cause side symptoms. But despite this, before carrying out treatment with Lekrolin, you need to consult a doctor and read the attached instructions.

Composition and mechanism of action

Lecrolin solution has a membrane-stabilizing effect. It prevents the allergen from reaching mast cells, releasing histamine and other allergy mediators. Due to this, the drug inhibits the development of the allergic process.

The most pronounced therapeutic effect is if the product is used for prophylactic purposes, since it does not affect the histamine that has already been released.

The drops contain cromoglycic acid, which is represented by disodium salt. It has a local antiallergic effect. After the start of instillations, the symptoms of irritation decrease, namely itching, burning, lacrimation, photophobia, redness and swelling of the conjunctiva.

Lecrolin is a 0.2% solution, 1 ml contains 20 mg of the active ingredient. Disodium salt does not penetrate into the systemic circulation and is slightly absorbed through the mucous membrane of the eye. Thanks to this, systemic side effects are excluded.

Description and instructions

Pharmacokinetics

The maximum proportion of cromoglycic acid in the blood when administered by inhalation is achieved in approximately minutes. Cromoglicic acid is very poorly absorbed from the gastrointestinal tract.
Only 8% of the medicine taken is absorbed into the blood. The half-life is about minutes (approximately 80 minutes on average). Cromoglicic acid does not accumulate in the body. It is easily and most importantly quickly excreted from it in its original form with the help of bile and urine in almost equal quantities. The remaining part of the drug is excreted by the lungs with the flow of air exhaled by a person, or, in extreme cases, accumulates on the walls of the pharynx, then is swallowed and leaves the body through the digestive tract.

When administered intranasally, less than 7.5% of the administered substance is absorbed into the blood. Cromohexal is successfully excreted after 24 hours through urine and bile (in equal proportions). It does not actually accumulate in the body.

Indications and contraindications

Drops can be used for eye allergies caused by any irritant. Indications for use:

• allergic conjunctivitis;
• allergic keratitis;
• keratoconjunctivitis;
• irritation caused by unfavorable environmental factors (dust, chemicals);
• drug allergy.

Drops reduce dryness, irritation and burning from contact lenses. They are used to prevent discomfort after keratoplasty.

The therapeutic effect after using Lecrolin eye drops should wait several days. Sometimes symptoms subside after 1-2 weeks. Efficacy depends on the severity of the allergy and the individual characteristics of the patient.

For seasonal allergies, it is worth starting instillations 2 weeks before the expected spread of the allergen. The development of an allergic reaction should be prevented before undesirable manifestations appear.

Lecrolin eye drops are contraindicated:

• individual intolerance to any component in the composition;
• children under 4 years of age.

Indications for use

Here are the indications that are indicated in the instructions for Lecrolin:

• allergic conjunctivitis, i.e. inflammation of the mucous membrane of the eyeball of an allergic nature (not infectious);
• allergic keratitis (allergic inflammation of the cornea);
• keratoconjunctivitis (a symptom complex that combines both of the above pathological reactions);
• irritation of the eye mucosa caused by physical and chemical factors (household chemicals, medications, industrial hazards, plant pollen, cosmetics, animal horny scales).

According to reviews of Lecrolin, the full antiallergic effect from using the drug can be expected in the range from several days to one to two weeks.

Directions for use and dosage

Before injecting the solution into your eyes, you should wash your hands with soap. Throwing your head back, place the bottle with drops above the eye, pull down the lower eyelid and inject 1-2 drops into the conjunctival sac. After administration, move the eyeball, blink, and tightly close the bottle of medicine. 4 instillations per day are enough.

During treatment, it is worth considering that the composition contains benzalkonium chloride. This substance is a preservative and can render contact lenses unusable. At the time of administration of the solution, they must be removed and put on after 15-20 minutes.

After opening the bottle, the drops are stored for no more than a month, then they must be disposed of. A closed bottle is stored for 3 years.

When using medicine in tubes, it is worth knowing that the solution does not contain preservatives. It must be used immediately after opening; it is not suitable for storage. A volume of 0.25 ml is sufficient for instillation into both eyes. The advantage of this form of solution is that it is harmless to contact lenses; they do not need to be removed while the drops are being administered. The product is also suitable for patients with hypersensitivity to preservatives.

Lecrolin eye drops instructions for use

Contents [Show]

Compound

Lecrolin drops contain 20 mg of sodium cromoglycate per 1 ml. 1 ml contains 25 drops, sodium cromoglycate per 1 drop is 0.8 mg.

The following additional substances are used: glycerin, Trilon B, polyvinyl alcohol , benzalkonium chloride (0.05 mg), water for injection.

pharmachologic effect

Lecrolyn belongs to the group of antihistamines . The medicine is an eye drop containing sodium cromoglycate , a substance that prevents the release of elements that cause allergic reactions in the mucous membrane of the eyes.

This drug is used to treat eye strain, seasonal allergies to natural irritants (for example, pollen) and systematic allergic reactions of various etiologies. Lecrolin eye drops are also prescribed for the treatment of conjunctivitis caused by exposure to various allergens.

This medicine is used to treat adults and children over 6 years of age. Using the drug without a prescription assumes that a certain diagnosis (confirmed by a doctor) has previously been carried out, and provided that the previously recorded symptoms have recurred.

The active substance of the drug is absorbed through the mucous membrane of the eye. However, systemic absorption is very insignificant.

Lecrolin is a topical antiallergic agent that has a membrane-stabilizing effect by preventing the release of mast cell granules into the surrounding tissue and the release of such biogenic compounds as histamine, bradykinin, and leukotrienes .

The drug has the greatest effect when used prophylactically. The absolute clinical effect is achieved with long-term and regular treatment.

Lecrolin eye drops are indicated for use for:

• conjunctivitis caused by allergens of various origins;
• keratitis caused by allergens;
• keratoconjunctivitis;
• irritation of the mucous membrane of the eye , which is provoked by various allergens (among the most common allergens: household chemicals, waste products of pets, pollen and other environmental factors).

Hypersensitivity to sodium cromoglycate , benzalkonium chloride or other components of the drug.

Like all medicines, Lecrolin eye drops have side effects, the most common of which is a temporary mild tingling sensation .

In addition, this drug can provoke an inflammatory reaction of the mucous membrane of the eyes due to the preservative benzalkonium chloride .

Possible adverse reactions include:

• burning sensation;
• blurred vision;
• local irritation.

Dosage for adults and children over six years of age: 1-2 drops in each eye twice a day, unless the doctor has prescribed individual doses due to certain characteristics of the course of the disease.

To achieve maximum effect, you should use anti-allergy eye drops regularly and strictly according to the instructions determined by a specialist.

Note: disposable containers containing the drug must be discarded immediately after use, even if there is still medication in them. After opening the disposable containers, the use of the drug is strictly prohibited.

If the effect of treatment with these eye drops is not achieved within a few days, you should consult a doctor for advice.

Before using eye drops:

• It is necessary to wash your hands thoroughly;
• choose the most comfortable position for eye drops (you can sit, lie on your back, stand or sit in front of a mirror);
• read the instructions for using the drug to avoid undesirable consequences.

Overdose

Animal experiments have shown that the local or systemic toxicity of sodium cromoglycate is very low.

When using the drug topically, symptoms of overdose are unlikely. If symptoms of overdose occur, symptomatic treatment should be used.

The active substance of the drug, as well as the auxiliary elements, do not have an effect in combination with other drugs, which has been established experimentally.

If it is necessary to use other eye drops for allergies as treatment, then this must be done at least 5 minutes apart.

Dispensed without a doctor's prescription.

Store at a temperature not exceeding 25 Celsius. Do not freeze and protect children from contact with the drug.

The shelf life of the drug is 3 years.

Analogues of Lecrolin include the following drugs:

• Allergo-Chest;
• Vividrin;
• Intal;
• Ifiral;
• Chrome allergist;
• CromoHexal;
• Cromogen;
• Cromoghlin;
• High Chrome.

Experts advise that before using this drug, read reviews about Lecrolin eye drops that were posted by users on the Internet. If we summarize the opinions of people who have used the drug, we can conclude that its positive effect occurs almost after the first use.

The most common property of the drops is that it instantly eliminates irritation and redness of the eyes with a single use. When treating allergic reactions, a positive effect occurs after several days or even weeks of topical application of drops.

The price of Lecrolin eye drops is affordable and, depending on the volume, varies from 86 to 89 rubles.

Lecrolin drops 20 mg/ml 10 mlSanten

Lecrolin 0.02/ml eye drops 10ml dropper bottle

Lecrolin1

LecrolinSanten (Finland)

Lecrolin h/c 40 mg/ml dropper bottle 5 ml Santen

Lecrolin h/c 40 mg/ml dropper bottle 5 ml Santen

Lecrolin 4% (40 mg/ml) 5 ml eye drops. bottle-dropper Santen (Finland)

Lecrolin 2% 10 ml eye drops.Santen (Finland)

Allergic eye diseases are a common and unpleasant phenomenon. The organ of vision is located in such a way that it is often exposed to various allergens. The causes of the disease can be pollen, animal hair, dust, etc. The cornea, conjunctiva and eyelids can be affected.

This problem affects both children and adults around the world. There are several types of antiallergic drugs. Mast cell membrane stabilizers are an effective and widely used group of antiallergic agents. This includes the drug Lecrolin.

Lecrolin - antiallergic eye drops. They contain sodium cromoglycate. An allergic reaction develops due to the release of special substances from mast cells. Mast cells are special immune cells that play a major role in the development of allergies due to the content of special substances. Among these substances, the main ones are histamine, bradykinin, etc.

They are responsible for the development of swelling, watery eyes, redness of the eyes and other signs of an allergic reaction. Sodium cromoglycate stabilizes (strengthens) the membranes of mast cells and thereby prevents the release of allergenic substances.

The drug is effectively used in the treatment of allergies

The drug does not work immediately. The full effect takes several days to several weeks to develop. But the effect lasts longer than when using the antihistamine group of antiallergic drugs. It will also be useful to know what antiallergic eye drops are.

The drug is made in Finland.

Available in two forms:

1. Bottle - dropper 10 ml of 2% sodium cromoglycate solution. Contains benzalkonium chloride. It can cause eye irritation and discolor contact lenses (you can use Renu solution for contact lenses). When using Lecrolin with preservatives, it is necessary to discard the lenses during instillation of the medicine; they can be put on again at least 20-25 minutes after using the drug.

   

1. Tube - dropper 0.25 ml 2% solution. Can only be used once. Does not contain preservatives. Required for patients with hypersensitivity to preservatives and those who wear lenses.

   

The drug in both forms of release contains polyvinyl alcohol. It increases the duration of action of sodium cromoglycate, makes the tear film more stable, and reduces lacrimation.

Indications for use:

• allergic conjunctivitis (damage to the mucous membrane of the eyelids);
• allergic keratitis (corneal damage);
• keratoconjunctivitis. But how acanthamoeba keratitis is treated is indicated here;
• eye damage due to exposure to occupational hazards, cosmetics and household chemicals, medications and other factors surrounding a person.

Lecrolin is the drug of choice in the treatment of chronic subacute allergic eye lesions.

Not used for bacterial and viral eye diseases.

Even during the first studies of Lekrolin in 1994 at the allergological center of the Moscow Research Institute of Eye Diseases, its high effectiveness was proven in 92% of those studied.

Contraindications:

• hypersensitivity to the components of the drug;
• It is not recommended for use in children under 4 years of age, since the effect of the drug in children has not been sufficiently studied.

The official instructions indicate that the drug should be used with caution in pregnant women and during lactation. This is true, however, due to the fact that the drug is practically not absorbed into the systemic circulation, Lecrolin is widely used in this group of patients.

The video shows the process of putting drops into the eyes:

Technique for proper eye drops:

• wash your hands thoroughly;
• shake the bottle;
• if you are using a dropper tube, unscrew the cap around the axis and open the tube;
• Move your head back. Pull down your lower eyelid and look up. Place 1-2 drops behind the eyelid (into the conjunctival sac). The medicine in one tube-dropper is enough to instill in both eyes.
• Close your eye and lightly press the inner corner of your eye with your fingertip for 2 minutes. This is important to increase the effectiveness of the drug and reduce systemic influence.

If there is medicine left in the dropper tube, you cannot use it the next time you use it. You need to throw away the tube.

The drug is prescribed to adults and children over 4 years of age. Instill 1-2 drops into the conjunctival sac four times a day at regular intervals. In severe cases, the number of uses can be increased to eight times a day. If signs of improvement appear, the frequency of instillation of the medicine should be reduced.

If you are allergic to flowering, you should start using the medicine immediately when the first symptoms appear. The course of treatment must be continued throughout the entire period of the disease. The same applies to cases if it is known in advance that it will not be possible to avoid contact with any other allergens. In this case, it is recommended to start using the drug in advance (if possible 1 week in advance).

Side effects.

• short-term burning of the eyes;
• blurred vision;
• swelling of the conjunctiva. But this article will help you understand how to distinguish allergic conjunctivitis from viral conjunctivitis;
• sensation of a foreign body in the eye;
• lacrimation;
• dry eyes. But what kind of drops there are for dry eyes and how to use them, the information at the link will help you understand.

These side effects can be caused by Lecrolin in a bottle using preservatives. No side effects were observed when using Lecrolin in a tube.

In ophthalmology, when applied topically, the drug does not have any systemic adverse reactions, since it practically does not penetrate into the general bloodstream. A maximum of 0.03% of the drug volume can pass into the blood, which has no significance or effect on the body.

Overdose. There were no cases of overdose. Local and systemic toxicity is negligible.

No negative symptoms were identified when interacting with any medications. Lecrolin reduces the need to use ophthalmic medications containing glucocorticosteroids.

Impact on the ability to drive a car and operate equipment.

After instillation of the medicine, loss of vision clarity and other symptoms of discomfort may occur. This may negatively affect the ability to drive a car and operate machinery. In this case, you need to postpone driving and working with equipment until your vision is restored.

Store the drug in a place protected from direct sunlight at a temperature of 15-25°C. An opened bottle can be stored for 1 month. When using, do not touch the eye tissue with the tip; after use, close the bottle tightly. The dropper tube cannot be stored after opening.

The average cost of the drug Lecrolin is 80-105 rubles.

Reviews

Review authors note the good effectiveness of Lecrolin, but not immediately. The drug begins to act after one to two weeks. Sometimes patients expect to instantly relieve allergy symptoms, which is why there are negative reviews. Some authors pay attention to the fact that it was possible to significantly reduce the use of ophthalmic glucocorticosteroids when used together with Lecrolin.

Patients report good tolerability of the drug and very rare occurrence of any adverse reactions or discomfort. Feedback from parents when used in children is positive. There are negative reviews that relate to the short shelf life of an opened bottle.

Lecrolin is an effective antiallergic drug. It is successfully used for the treatment of chronic subacute allergic eye lesions. Has a longer duration of action, unlike antihistamines. The advantage is that there are two release options.

One of them is Lecrolin in a tube - a dropper without preservatives, which is important for people with allergies to preservatives and for those who wear lenses. The drug rarely causes side effects and can be used in children from 4 years of age. There are analogues of Lecrolin. But they are almost similar both in price and in all medicinal parameters.

With the help of vision, a person receives more than 90% of all information. Every second our eyes perceive, and our brain recognizes thousands of images, but sighted people rarely think about this. But still, one of the tasks of doctors is to convey to patients how important it is to protect their body from any, even minimal, pathology, and therefore so many medications have been invented for almost all diseases. In this article you can find information on the drug “Lecrolin” (eye drops). Instructions, price, analogues, method of application - you will find all this in separate paragraphs.

The active substance in the above preparation is sodium cromoglycate, that is, a salt of cromoglycic acid. On its basis, pharmacologists have created many medicines that primarily have membrane-stabilizing properties, causing anti-allergenic and anti-asthmatic effects. The fact is that when an irritant enters the human body by any means (airborne, contact, sexual, food, etc.), first a local and then a systemic response develops, caused by the immune system and its cells. One of them are basophils, which, when they enter the tissue space, acquire the name “obese”. The drug “Lecrolin” (eye drops) directly affects them.

This is necessary because inside these cells there are many granules with biologically active substances: histamine, prostaglandins, interleukins, chemotactic and tumor necrosis factors. Therefore, when basophils enter the immune reaction, they degranulate, and through the membrane, all these inflammatory mediators begin to be released, attracting other immunocompetent cells. And the product “Lecrolin” (eye drops), the instructions for which contain all this information in brief, stops the above processes, stabilizing mast cells and deactivating them. Thus, it persistently relieves inflammation even before the most violent phase, when migration of other cells to the lesion has already occurred, which means that the disease is stopped more easily and quickly.

Since this active substance has such a pronounced antiallergic effect, and this occurs even in the first stages of the reaction, it is also used in other medicines. Therefore, it is possible to treat according to a whole scheme, that is, by combining several drugs to achieve a speedy remission. Thus, with hay fever, the most common manifestations are allergic conjunctivitis and keratitis, for which, by the way, Lecrolin drops are used. Reviews about it in the treatment of this pathology are positive, even from those patients who use it periodically for quite a long time. Another common manifestation of an allergic reaction to plants is rhinitis, for which it is better to use a nasal spray with cromoglycic acid as the active substance. It also exists in inhalation form, in which it is widely used to treat bronchial asthma. But there are also capsules for the treatment of food allergies.

In addition to cromoglycic acid at a dosage of 20 mg, this drug contains water for injection, benzalkonium chloride, boric acid and disodium edetate. The selection of such a combination is necessary to maximize the effectiveness of the drug and achieve a therapeutic effect with a minimum of side effects. “Lecrolin” (eye drops), the instructions for which necessarily contain detailed information about this medicine, are available in the form of dropper bottles (10 ml) or tubes (0.25 ml) to make it convenient to use. Of course, this is an absolutely sterile product that has a certain shelf life and storage conditions. Therefore, if the course of treatment prescribed by the doctor is not so long, then it is better to purchase a small volume tube, since it is undesirable to use the drug after it has been stored for a long time at home. In appearance, the medication "Lecrolin" - eye drops - is a transparent solution without suspensions or impurities, but it may also have a slightly yellowish tint.

Of course, this drug is not the only one in which the active substance is cromoglycic acid. The following drugs have also been created on its basis: the English “High Krom”, the Romanian “Krom-allerg”, the German “Allergo-Komod” and “Cromoglin”, as well as the Indian “Ifiral”. All of them are officially registered and have differences in price and minimal differences in effectiveness. However, the drug "Lecrolin" - eye drops - was widely used. Reviews about it are generally positive, especially when it comes to preventive use. In terms of therapeutics, it may be somewhat inferior to foreign drugs, but not significantly. Therefore, when choosing a medicine, you should be guided only by your own preferences and financial capabilities.

Since the main effect of the drug "Lecrolin" is anti-allergic, it is indicated for various diseases of the organ of vision of this particular etiology. These include conjunctivitis, keratitis or keratoconjunctivitis, as well as minor irritation of the mucous membrane of the eyes caused by any allergenic factor: occupational hazards (dust and gas pollution in the room, heavy industry, chemical products), decorative cosmetics, environmental factors, pollen, animal hair, as well as medications used in ophthalmology, but to which this patient has an intolerance.

Are there any contraindications to the use of Lecrolin (eye drops)? The instructions, which are necessarily included in the package with the drug, also inform that intolerance not to cromoglycic acid, but to the auxiliary components of the drug, is more common. For example, it could be benzalkonium chloride or disodium edetate. Therefore, if you notice an inadequate reaction to the instillation of the drug "Lecrolin", then you must immediately stop administering it and, preferably, rinse your eye with simple drops of sterile water or take other antiallergic drugs. A method of reinsurance is to block the nasolacrimal duct by pressing the index finger to the place of its projection, this will prevent the systemic effect of the allergen. In addition, it is prohibited to use it in children under 4 years of age, and with caution in pregnant and lactating women.

Lecrolin eye drops, like many ophthalmic drugs in solutions, require instillation of 1-2 drops 3-4 times a day into each conjunctival sac, but the more precise dosage is determined by the doctor. In a therapeutic dose, this drug should be used only until signs of inflammation of the eye membranes completely disappear. If disease prevention is necessary in the off-season, then it can be continued at a lower dose. Usually there are no side effects from this drug and it is well tolerated. However, at the first appointment, the patient may feel a slight burning sensation in the eyes, local irritation or blurred vision, which passes extremely quickly. For this reason, it should be used with extreme caution by patients driving a vehicle. Or you should wait until the above phenomena stop and only then get behind the wheel.

It is also important to know how Lecrolin eye drops interact with other medications. Its instructions indicate only glucocorticosteroids, which, when used concomitantly, can reduce the effectiveness of the latter. If the patient wears contact lenses, then before installing the drug “Lecrolin” they should be removed and put on at least 15 minutes after the procedure, this is due to the destructive effect of sodium benzalkonium on them. It is also important to remember that when instilling the product, you should not touch the tip of the pipette or bottle to the eye membranes, and after use, you should screw it tightly. And the medicine should be used within a month after opening the bottle.

Lecrolin is an antiallergic drug for local use in ophthalmology, which has a membrane-stabilizing effect.

Lekrolin is produced in the form of eye drops: a colorless or pale yellow transparent solution (10 ml in a white polyethylene bottle, sealed with a plastic dropper stopper with a screw cap, 1 bottle in a cardboard box; 0.25 ml in a dropper tube, in an aluminum bag foil and paper coated with polyethylene, 10 pieces soldered in the form of a plastic tape, 2 bags in a cardboard box).

1 ml of solution contains:

• active ingredient: sodium cromoglycate – 20 mg;
• auxiliary components: polyvinyl alcohol, glycerol, disodium edetate, water for injection; additionally in solution in a dropper bottle - benzalkonium chloride.

Pharmacodynamics

Lecrolin is an antiallergic drug, a stabilizer of mast cell membranes. The mechanism of action of the drug is to inhibit the process of degranulation of mast cells and, as a result, to suppress the release of biologically active substances from them, leading to the development of allergic reactions, including bradykinin, histamine, leukotrienes (including a slow-reacting substance). Lecrolin demonstrates the greatest effectiveness when used prophylactically. Against the background of allergic diseases, the absolute clinical effect can be achieved after several days or weeks of drug therapy.

Sodium cromoglycate is absorbed to a small extent through the mucous membrane of the eye. The half-life of the active substance is 5–10 minutes, systemic bioavailability is less than 0.1%.

Contraindications

• age up to 4 years;
• hypersensitivity to any of the components of the antiallergic drug.

Instructions for use of Lecrolin: method and dosage

Lecrolin eye drops are recommended to be administered into the conjunctival sac. The initial dose is 1-2 drops in each affected eye 4 times a day with an interval of 4-6 hours. If necessary, the frequency of administration can be increased to 6–8 times a day. Instillation of the drug should be carried out until the symptoms of the disease are completely relieved.

Treatment of seasonal allergic conjunctivitis should be started immediately after the first symptoms of the lesion appear; for preventive purposes, Lecrolin should be used before the expected contact with the allergen, i.e. before the pollen season. Therapy must be continued throughout the flowering season or longer if symptoms persist. If within several weeks of using the drops the expected therapeutic effect cannot be achieved, you should consult your doctor.

Lecrolin eye drops, produced in dropper tubes, do not contain a preservative that slows down the healing process of corneal and conjunctival wounds, as a result, these drops can be administered to patients with hypersensitivity to preservatives.

Before using Lecrolin in a dropper tube, open the package containing the drug along the dotted line. After separating one of the outer dropper tubes, the bag must be carefully closed. After making sure that the solution is at the bottom of the dropper tube, the latter must be opened and 1-2 drops of the solution injected into the conjunctival sac of each eye. The dose contained in the tube is sufficient for instillation into both eyes; the drug remaining after a single use cannot be used.

When applied topically, cromoglycic acid is generally well tolerated and rarely causes signs of eye irritation. These symptoms of local irritation include:

• often (more than 1/100): short-term burning sensation, quickly passing blurred vision;
• extremely rare (less than 1/10,000): lacrimation, dry eye syndrome, sensation of a foreign body in the eye, swelling of the conjunctiva, allergic reactions; in the presence of benzalkonium chloride in Lecrolin - meibomitis and superficial damage to the corneal epithelium.

Animal studies have revealed an extremely low degree of local and systemic toxicity of cromoglycic acid. In the case of topical use of sodium cromoglycate, the appearance of overdose symptoms is unlikely. However, if an overdose is suspected, for example, symptoms such as nausea occur, symptomatic treatment is recommended.

Since the drops in dropper bottles contain the preservative benzalkonium chloride, they should not be used when wearing contact lenses. Before instillation, it is recommended to remove contact lenses and reinsert them no earlier than 15 minutes after instillation of the product.

Since drops in dropper tubes do not contain a preservative, they can be used by patients wearing contact lenses of any type.

The bottle with the drug must be closed after each administration. Do not allow the tip of the pipette to touch your eyes.

If a temporary loss of clarity of vision occurs after the administration of Lecrolin, patients are not recommended to drive vehicles or other potentially dangerous and complex mechanisms immediately after using eye drops.

During pregnancy and breastfeeding, ophthalmic drops can be used when the expected benefit of treatment for the woman outweighs the possible risk of side effects for the fetus/child.

According to the instructions, Lecrolin is contraindicated for use in children under 4 years of age.

To date, cases of adverse interaction of cromoglycic acid with other drugs have not been described.

The use of this active substance can help reduce the need for the use of ophthalmic drugs, which include glucocorticosteroids.

Analogues of Lecrolin are: Allergo-Komod, CromoHEXAL, Kromospir, Intal, Dipolkrom, High-Krom, Krom-allerg, Nalkrom, Optivell, Cromoglycic acid.

Store in a place protected from light, out of reach of children, at a temperature of 15–25 °C.

Shelf life - 3 years, after opening the package with a dropper tube or dropper bottle - 1 month.

Available without a prescription.

On medical websites, reviews about Lecrolin are in most cases positive. Patients treated with the drug note its high effectiveness in eliminating irritation and redness of the eyes; these symptoms, according to their reviews, are relieved even with a single use of drops. It is also indicated that Lecrolin demonstrates very good results when used before the flowering of the plant that provokes the disease, for the prevention of seasonal allergic conjunctivitis. When treating allergic reactions, improvement may be observed after several days or weeks of using the drops. The advantages of the product also include its availability and low cost.

However, there are reviews that indicate an insufficient or too short-term effect of the drug; some patients note the development of addiction. The disadvantages of the drops include the appearance of a white film on the eyelashes and eyelids after their administration. There are very few complaints about the development of adverse reactions.

The price of Lecrolin can be 75–95 rubles per 10 ml dropper bottle.

Use in special patient groups

The drug has a local effect, so it can be used in children and pregnant women.

Children

The medicine can only be used when the child reaches 4 years of age. The dosage and treatment regimen are the same as for adults. There is a practice of using drops for patients under 4 years of age. But such therapy is carried out only under the strict supervision of an ophthalmologist.

Pregnant and nursing

Allergy eye drops can be used during pregnancy and breastfeeding, but with caution. There are no contraindications in the instructions, but safety has not been proven.

Nasal drops, or how to quickly get rid of allergies

Allergy nasal drops will help against a runny nose, itching, and congestion.
Allergies can rightfully be considered one of the most annoying diseases. Its symptoms are extremely unpleasant: itching, swelling, redness, bronchospasms, hearing loss, swollen nose, runny nose. Allergy nasal drops will help against a runny nose, itching, and congestion.

Types of nasal drops for allergies:

• Hormonal;
• Vasoconstrictors;
• Immunomodulatory;
• Antiallergic;
• Combined.

The meaning of drugs

Hormonal drugs are used in severe cases, when other methods are ineffective. The most common: Avamys, Flexonase, Dexamethasone.

Vasoconstrictor medications relieve a runny nose for up to several hours and relieve swelling of the nasal mucosa. Recommended for a short period. It is not advisable to use it for more than 5 days; therefore, these remedies are only good in emergency cases. These drugs include: Nazivin, Naphthyzin.

Immunomodulatory drugs perfectly help cope with allergic rhinitis and rhinosinusitis. For example, Vilosen is a drug against pollen allergies.

Antiallergic drugs contain antihistamines. Due to the cessation of the release of allergy mediators, the symptoms are relieved. Such drugs include nasal and eye drops: levocabastine, Allergodil, Zyrtec, lecrolin, fenistil, cromohexal.

Combined medications have a complex effect. They are at the same time antiallergic, anti-inflammatory, and vasoconstrictor. The drugs act instantly and the effect lasts for a long time. This group includes nasal drops: Sanorin-allergin, Vibrocil.

Selected drugs

Let's look at the most effective drops for nasal allergies: these include not only nasal, but also eye drops. Preparations intended for the eyes can also be used for the nose, since the medicinal components are equally absorbed into the bloodstream from these organs:

1. Lecrolin eye drops or Lecrolin nasal spray. Lecrolin prevents the occurrence of allergic and inflammatory reactions and prevents the occurrence of bronchospasm. Lecrolin should not be used if you are hypersensitive to the components of the medication, if you have nasal polyps, or during the lactation period. Lecrolin should be discontinued by gradually reducing the dose over the course of a week. Lecrolin can be dripped into the eye and nose; you can use Lecrolin nasal aerosol. You need to drip 1.4 times a day. Aerosol lecrolin 1 dose 3 times a day. It is advisable not to use lecrolin for those who have problems with the liver and kidneys. The course of treatment with lecrolin is 4 weeks.
2. Fenistil nasal drops for allergies. The use of the drug fenistil is allowed even for children from 1 month of age. Fenistil stops itching of any origin. For bronchial asthma, fenistil is not recommended. Fenistil should be used with caution in children under one year of age. Fenistil is prescribed three times a day. For children from 1 month of life, 5 drops. In terms of effectiveness and safety, fenistil is superior to tavegil and suprastin. Side effects of the drug fenistil: a feeling of dryness and burning, itching, skin rash. Fenistil is not prescribed for patients with bronchial asthma.
3. Cromohexal nasal drops. Has a membrane-stabilizing effect. Cromohexal is used against allergic rhinitis (mild severity) and hay fever. Cromohexal is available as a nasal spray. The effect occurs only after use for more than 5-10 days. The course of treatment is 4-16 weeks. Cromohexal can be used all year round. Cromohexal has side effects manifested by coughing, sneezing, difficulty swallowing, itchy skin, headache, bronchospasm, hemoptysis, congestion, lacrimation, nausea. Cromohexal is contraindicated during lactation, children under 5 years of age, and pregnant women. Cromohexal should be administered with caution to people suffering from renal or hepatic colic, or with polyps. Cromohexal should be used only on the recommendation of your doctor. Cromohexal can be combined with other drugs.
4. Zyrtec nasal drops are a new generation antihistamine. Zirtec against allergies is available in pharmacies without a prescription. Zyrtec is contraindicated in children under 6 months of age. Used for allergic rhinitis and conjunctivitis, allergic dermatoses. Zyrtec should not be used during pregnancy or while breastfeeding. Zyrtec is well tolerated, Zyrtec has no side effects. It is better to avoid alcohol while using Zyrtec.
   Dosage regimen

   For children under one year old, drop 1 drop into each nostril once a day. Children from one to 6 years of age are given the product diluted in water in an amount of 5 in each nostril. Can be divided into two steps. For children from 2 to 6 years old, Zyrtec is also dissolved and given the norm per day in two doses. Older children should take 10 drops in pure form in the morning and evening.

   Allergy drops are considered the most gentle remedy against allergies. Before instillation, children need to thoroughly clean their nasal passages. Zyrtec has side effects: headache, drowsiness, decreased attention, fatigue. Zyrtec is contraindicated for children under 6 months, pregnant and nursing mothers.

   Zyrtec should be used with caution in case of renal failure and in old age. Zyrtec is rapidly absorbed.

5. Dexamethasone. Dexamethasone belongs to the group of glucocorticosteroids. The hormone dexamethasone is used against allergies and inflammation. Dexamethasone is part of Polydex spray. The drug is indicated for rhinitis, rhinopharyngitis, sinusitis. Polydex with phenylephrine has a complex effect: phenylephrine facilitates breathing, constricts blood vessels, neomycin and polymexin B kill pathogenic microorganisms, dexamethosone itself successfully copes with inflammation. Treatment with dexamethosone as part of the drug Polydex lasts 5-10 days. The drug is not recommended for children under 12 years of age. Dexamethasone is contraindicated in pregnant and breastfeeding women.

You can use dexamethasone eye drops against allergic manifestations. Adults 3 times a day, but not more than 7 days. Dexamethasone works well in emergency cases.

1. Eye drops allergophtal, allergodil are effective against allergic conjunctivitis.

Nasal products for little ones

Self-prescribing treatment for your child is contraindicated; entrust the recovery of your children to the hands of specialists. For allergies, instead of treating symptoms, it is better to find the allergen and eliminate it. Sometimes simple things can help newborns get rid of a runny nose:

• The air temperature should not be more than 22 degrees;
• Room air should be moist and fresh;
• Crusts covering the nasal cavity of children should be removed in the evenings with cotton swabs.
• Rinsing the nose of newborns with saline solution and drinking plenty of fluids.

Description of some drugs

1. Aquamaris is safe, contains sea water without any harmful additives. Can be used from the first days of birth. Drop 5 times a day into each nasal passage, 2. Aquamaris in newborns softens crusts, moisturizes the mucous cavity, and is used for rhinitis, adenoids, and sinusitis.
2. Salin is a saline solution with additional components. Makes breathing easier, removes mucus and crusts. For newborns - 1 unit 1-2 times a day.
3. Nazol baby.
   Used to treat rhinitis in children. The drug instantly relieves congestion. Do not use for more than 3 days, more than 2 times a day.

Instructions for instillation

To instill medication into the eye, you need to make sure you have a clean, new pipette. Before instilling the drug, it is necessary to rinse each eye with a swab soaked in boiled water.

It is necessary to clean in the direction from the outer edge of the eyes to the inner. Pull back the lower eyelid slightly and drip the product without touching the eye with the pipette.

In this case, you need to make sure that the liquid does not get from one eye to the other eye.

Clear your nasal passages to keep them clear. Warm the bottle with your palms and inject the liquid into your nose with a separate pipette, with your head thrown back.

Whatever drops you use to save yourself from allergies: eye or nasal, remember that you can only get rid of allergies through comprehensive treatment and only under the supervision of a doctor.

on this topic

The article is presented for informational purposes. Treatment should only be prescribed by a doctor!

Source: https://allergyall.ru/pro-allergiy/kapli-v-nos.html

Side effects

According to the instructions for use, immediately after the administration of eye drops, symptoms of irritation may occur - mild burning, tingling, redness and blurred vision. These signs are normal and disappear within a few minutes.

If the symptoms of irritation do not go away or get worse, you should stop treatment and visit a doctor.

After instillation of the solution, you should not immediately drive or begin work that requires a high concentration of attention. It is necessary to wait 5-10 minutes until vision clarity is completely restored.

Very rarely, after using Lecrolin, allergic manifestations and lesions of the corneal epithelium occur. Overdose is unlikely due to the low toxicity of the active substance. In case of overdose, symptomatic therapy is indicated.

Analogs

Analogues of Lecrolin for the active substance are:

• Chrome allergist. These are eye drops based on cromoglycic acid. Indications for use are acute and chronic forms of allergic conjunctivitis. Cost about 80 rubles.
• Cromohexal. This is an ophthalmic solution of cromoglycic acid. Has anti-allergic and anti-inflammatory effects. The cost of 10 ml is about 120 rubles. Read more about Cromohexal→

Lecrolin 10 ml costs 120 rubles.

Allergodil drops have an antiallergic effect. They are represented by a 0.05% azelastine solution. Indication for use is allergic conjunctivitis. The drug has a powerful antiallergic and membrane-stabilizing effect; it is not used for children under 4 years of age or in the first trimester of pregnancy. The course of treatment is no more than 1.5 months. The product is expensive. For a 6 ml bottle you need to pay 520 rubles.

Another expensive substitute for Lecrolin is Opatanol. Active ingredient: olopatadine. Contraindication for use is intolerance to the components in the composition. The product is available in 5 ml dropper bottles. Cost 650 rub.

Allergies should not impair your quality of life. If the patient has a seasonal predisposition, it is worth taking care of eye health in advance.

Leave your feedback on the use of Lecrolin eye drops in the comments.

Author: Oksana Belokur, doctor, especially for Okulist.pro

pharmachologic effect

The main “actor” of Lecrolin drops, cromoglycic acid, belongs to the so-called mast cell membrane stabilizers . Perhaps not everyone knows what mast cells are. These are specialized cells that participate in the body's immune response to the invasion of a foreign agent and are directly involved in allergic and inflammatory processes. So: by stabilizing the cell membrane, cromoglycic acid prevents the release of inflammatory mediators (histamine, leukotrienes, lymphokines, etc.), thereby stopping inflammation and other allergic manifestations.

Such a pharmacological effect has made it possible to gain positive reviews of Lecrolin from patients, since these drops reduce the need for glucocorticosteroids, often used for conjunctivitis. Well, judging by the reviews of Lecrolin, this drug has also proven itself in the prevention of allergic reactions in ophthalmic practice.

It should be noted that Lecrolin drops are ineffective for conjunctivitis caused by bacteria or viruses.