Staloral "Mite Allergen" bottle (sublingual drops) 300 IR/ml 10 ml No. 5 per dose. Stallergenes/France

General description of the drug

House dust mites are responsible for a huge number of chronic allergic reactions. This type of allergy itself is not dangerous (with the exception of occasional cases of the development of terminal forms of allergy), but it seriously interferes with the patient’s life.

In such situations, patients usually resort to drug therapy, which does not cure the disease, but puts it into remission as long as the drug (antihistamine) is taken. To completely get rid of allergies to house dust mites, desensitizing drugs were invented, including Staloral.

Staloral for the treatment of pollen allergies

This drug is designed to either significantly reduce the manifestation of allergy to mites in the patient, or completely rid the person of this problem. It is extremely difficult to predict the final effectiveness of treatment, but in general, such drugs can improve the quality of life for the vast majority of patients (more than 80% of patients are cured to one degree or another).

Treatment with the drug Staloral takes place in two stages: main treatment (initial course) and subsequent maintenance therapy.

Indications for use

The undoubted indication for the use of this medication is the presence of a severe allergic reaction to house dust mites.

Bottle with the drug Staloral

It is impossible to make such a diagnosis right away, since mites are simply not visible to the human eye, so you need to contact an allergist for a diagnosis if the following symptoms develop:

• tearing and redness of the eyes upon contact with house dust, sneezing, coughing, the appearance of dermatitis on the skin;
• upon contact with house dust, the general condition deteriorates significantly;
• shortness of breath or simply difficulty breathing when in contact with house dust;
• development of bronchial asthma against the background of complete well-being (the person does not smoke, does not work in chemical production, and so on).

After visiting a doctor and analyzing house dust, an accurate diagnosis can be made. It is for this disease that Staloral “Tick Allergen” is used, but this medicine also has other types intended to treat allergic reactions from other triggers (pollen, plants, insects, and so on).

Allergen Staloral (video)

Release form and composition

The drug Staloral "Mite Allergen" (registration number -LSR-008340/10-180810) is available exclusively in the form of sublingual drops with a volume of 10 milliliters. The medicine is in a bottle with a convenient dispenser.

The main active component of the drug is an allergen extract from house dust mites of the species Dermatophagoides pteronyssinus and Dermatophagoides farinae. The allergen extract is distributed in different proportions: 10 IR/milliliter and 300 IR/milliliter.

IR/milliliter is a reactivity index that is a biological unit of standardization.

Excipients of the drug are:

• purified water;
• mannitol;
• glycerol;
• sodium chloride.

Box with vials of the drug Staloral

Normally, the medicinal solution is transparent . Color range: from colorless to yellow-brown. There should normally be no sediment at the bottom of the bottle with the medicine.

Contraindications

• The presence of individual intolerance or hypersensitivity to substances included in the drug.
• A history of autoimmune diseases, immunocomplex diseases and immunodeficiency conditions.
• The presence of malignant neoplasms.
• Uncontrolled bronchial asthmatic disease in severe form, with forced expiratory volume less than 70%.
• Carrying out a therapeutic course of beta-blockers.
• Manifestations of inflammatory processes in the oral mucosa in severe form.
• Age indicator up to five years from the time of birth.

Initial and maintenance courses

The drug Staloral has two special kits designed for initial therapy and subsequent maintenance therapy.

The drug is divided into the following courses:

1. Staloral "Mite allergen" - initial course.
2. Staloral "Mite Allergen" - maintenance course.

The initial course kit includes a bottle with an allergic trigger extract at a concentration of 10 IR/milliliter, two bottles with a concentration of 300 IR/milliliter, three dispensers and instructions for using the drug. This kit is intended for patients with an allergic reaction to type 1 mites.

The maintenance course kit includes two bottles with an allergic trigger extract at a concentration of 300 IR/milliliter, two dispensers and, accordingly, instructions for using this product.

Vials with drugs are in special plastic boxes that protect the vials from shock and contamination. When purchasing a medicine, you should pay attention to the expiration date (located on the box), since an expired expiration date not only reduces the effectiveness of treatment to zero, but can also cause severe complications.

Overdose

To date, there is no data on possible negative effects when using a larger amount of the drug, the maximum dose.

When using Staloral, the following negative symptoms may occur on the part of the patient's body:

Hematopoietic and lymphatic system: lymphadenitis is rare.

Immune system: rarely hypersensitivity reactions, symptoms of serum sickness.

Nervous system: rarely, pain in the head area, sensitivity disorders.

Visual apparatus: often itching in the eye area, rarely itching in the ears.

Respiratory system: often the development of swelling of the throat, the occurrence of a runny nose and cough, the formation of blisters in the mouth and throat, as well as irritation of the mouth and throat; rarely, exacerbation of asthmatic disease, shortness of breath, hearing disorders and the occurrence of inflammatory processes in the nasopharyngeal mucosa.

Analogs

The product has several domestic and foreign analogues. Among them:

1. Series "Staloral" from the same manufacturer. It differs in the form of release - these are sublingual drops. The remaining characteristics are identical to Alustral. It usually costs more.
2. Lais Dermatophagoides is an Italian remedy for. Available in tablet form. It has fewer side effects and a lower risk of complications in case of overdose.
3. “Mix mixture” from a Czech manufacturer. Available in the form of drops. It has a small number of side effects.
4. Biomed products. It is distinguished by a wide selection of allergens and a low price - from 250 to 450 rubles per package. The mixtures are intended for injection course.

Adverse reactions

Alustal, like any other potent drug, has a number of side effects. The likelihood of their occurrence depends on the individual characteristics of the patient and the conditions of the course. Possible unpleasant accompanying sensations are presented in the table:

The listed reactions were identified at the stage of clinical trials. The practical use of Alustal in medical practice has revealed other consequences:

• swelling of the larynx;
• wheezing in the throat;
• vomit;
• physical discomfort;
• asthenic conditions;
• swollen lymph nodes;
• joint pain;
• muscle pain;
• inflammation with the formation of nodules;

The occurrence of any of these effects requires immediate medical attention.
In special cases, depending on individual tolerance to a particular allergen, a severe allergic reaction may occur, which manifests itself in the form of severe itching, rashes, abdominal pain, increased blood pressure, fainting and dizziness. This case is especially dangerous and requires prompt medical intervention.

Additionally

The immunotherapeutic course can be carried out in patients over five years of age.

Before starting treatment, it is necessary to review the patient's medical conditions.

If the patient's condition worsens during therapy, it is necessary to inform the doctor.

Before carrying out a therapeutic course, steps should be taken to stabilize allergic symptoms.

In case of allergic manifestations, it is possible to use glucocorticosteroids, antihistamines and β2-adrenergic agonists.

Allergen-specific immunotherapy is carried out with extreme caution in patients undergoing treatment with cyclic antidepressants, as well as drugs that have properties that inhibit monoamine oxidase activity.

In the presence of inflammatory processes in the oral cavity, in particular aphthae, mycoses, ulcerations, tooth loss, and the postoperative period of surgical interventions in the oral cavity, it is necessary to interrupt the therapeutic course until the inflammatory processes completely stop.

If during the therapeutic course symptoms of digestive system disorders occur, in a severe form, which are manifested by swallowing disorders, painful sensations in the chest, you should immediately stop using the medicine and consult your doctor. The decision about the possibility of further continuation of therapy is made by the doctor.

When carrying out dietary measures with a reduction in salt, it should be remembered that ten milligrams of the medicine contains 590 milligrams of sodium chloride.

When transporting the drug, it is necessary to ensure its vertical position and the presence of a protective ring.

pharmachologic effect

The drug, regardless of the specific active ingredient, affects the body. This means that the remedy:

1. Promotes the appearance of antibodies that resist the allergen.
2. They provoke an immune response - the immune system remembers the allergen for a long period and adapts to suppress it.
3. Reduces the degree of reactivity of cells that take part in allergic reactions.

The drug helps increase the body's resistance to irritants at the cellular level.

special instructions

Alustal is a potent drug, and several factors should be taken into account when using it. Among them:

1. Each bottle contains a different concentration of the active substance , so the order of use should not be changed.
2. The drug is very demanding in terms of dosage ; it must be calculated strictly according to the instructions; changing doses is permissible only in special cases. This decision is made by an allergist.
3. The drug should be injected only under the skin . The introduction of Alustal into blood vessels can provoke unpleasant consequences.
4. Session intervals also cannot be changed , especially in the direction of increasing frequency. If therapy is interrupted for one reason or another, it also continues according to the instructions, where there are special dosage instructions for these cases.
5. Treatment can begin only after stabilizing anti-allergy therapy , taking into account the general health of the patient and his individual sensitivity to the active substances.
6. In addition, the therapeutic course is incompatible with infectious diseases .
7. Treatment should be stopped if the patient has suffered an asthmatic attack .