A disease such as psoriasis has been causing unprecedented pain and discomfort to humans for many centuries. The reason for its appearance has not been fully studied.
Modern medicine offers many options for treating and eliminating the manifestations of this disease.
Among the variety of these drugs that have appeared in Russia, one can highlight the drug “Stelara”, which is available in the form of injections.
Consider in detail the characteristics and properties of this medicine, as well as the instructions for its use.
Features of the drug
Stelara is a medicine that is a highly potent immunosuppressant. Its effect is expressed in the suppression of the human immune system, which causes protein synthesis to stop. This is what most often causes the disease to appear.
Most experts talk about psoriasis as a psychosomatic disease. In skin cells, pathological processes can start in response to stress, severe psycho-emotional stress, and other problems with the activity of the nervous system. In addition to affecting the cause of the disease, the medication can also work with the nervous system, reducing tension and having a beneficial effect on the quality of sleep.
According to the instructions, Stelara can be used in therapy when working with psoriasis in various forms and at any stage of the disease. Suitable for especially advanced cases. The drug has a significant positive effect on the course of the disease, improves well-being, and helps to recover faster.
How Stelara works in the body
Another name for the drug is Ustekinumab, based on the main active ingredient. It is classified as an immunosuppressant, the effect is expressed in the fact that under the influence of the medication there is a strong inhibition of the synthesis of two types of proteins.
The proteins that are affected by Stelara psoriasis injections trigger the uncontrolled process of epidermal cell division. This is the main reason for the appearance of psoriasis.
The medication contains the following substances:
- Ustekinumab, which is the main active component;
- Water for injections;
- Sucrose as an auxiliary component;
- Polysorbate;
- L-histidine hydrochloride monohydrate.
The good effectiveness of the drug Stelara has been scientifically proven. The medicine, entering the human body, begins to work from the inside. In this case, the impact is exerted on the main causes that caused the disease, and its subsequent development is prevented.
Composition of the drug "Stelara"
The active ingredient of Stelara is ustekinumab. The drug itself is classified as an immunosuppressant; another name for such drugs is biological drugs. The ampoule may contain 45 mg and 90 mg of the active ingredient. In addition to it, the composition contains auxiliary substances - water, histidine, sucrose, polysorbate.
"Stelara" is available in ready-made syringes, which greatly facilitates the administration process. It is recommended to give injections in medical institutions.
Beneficial features
Ustekinumab is a human antibody synthesized in the laboratory (therefore the drug is classified as biological). The essence of the medicinal properties is to block the activity of mediators of autoimmune inflammation - the so-called interleukins. This mechanism also inhibits the further production of other proteins responsible for the development of psoriasis.
More specifically, Stelara affects interleukin-12 and interleukin-23. It is these two substances that are the basis of autoimmune inflammation, which is the cause of the development of psoriasis.
Patients are diagnosed with a decrease in the number and size of plaques, the intensity of itching and hyperemia of the skin is significantly reduced. Normalization of sleep is also noted. An improvement in the clinical picture is reflected in general well-being; patients become less emotionally labile. In general, the drug promotes effective treatment and transfers the disease into a state of remission, which can last for years.
The benefits of drug injections
Stelara injection solution, which contains ustekinumab, has many beneficial abilities for the body. The action of injections directly affects the implementation of histological processes and overall health. Even after one injection, most patients already feel a change in their condition.
If the disease is mild, the use of Stelara is considered inappropriate from both an economic and medical point of view. Taking into account its strong effectiveness for the whole body, it is worth prescribing only for particularly severe conditions. If conventional therapy for a disease is ineffective or there is a significant risk of various complications, in such cases it makes sense to turn to more effective medications.
The decision to carry out treatment using monoclonal antibodies should be made by an experienced physician. You cannot independently include such medications in therapy. What are the benefits of using the drug Stelara:
- The medication actively has a healing effect on the human body;
- Metabolic processes are normalized;
- The body's resistance to disease is significantly improved, the formation of pathological intracellular processes is slowed down;
- With regular use of the drug, the discomfort accompanying dermatological diseases decreases, the skin areas affected by the disease stop reddening and peeling, and the burning and itching go away. The skin condition becomes close to normal;
- There is a gradual restoration of the psycho-emotional state, difficulties with falling asleep disappear, the patient begins to feel lightness and bursts of energy.
Stelar injections can be prescribed to treat the plaque type of the disease, in some cases with psoriatic arthritis. More often it is used as a drug for monotherapy, but it is also quite successfully used as part of a complex to get rid of psoriasis. There is a good effect in late stages of the disease, especially in advanced, serious conditions.
be careful
People suffering from psoriasis often make one big mistake:
The patient is trying to eliminate the external signs of the disease, but eliminating the external manifestations of psoriasis does not solve the problem from the inside.
Roughly speaking, even if it is possible to remove the signs of psoriasis from the outside and put the skin in order, inside the body the disease continues to devour the autoimmune system, which provokes severe diseases, many of which are fatal. Particularly scary is the fact that psoriasis can provoke cancerous tumors.
The only remedy that is currently available for self-use by patients with psoriasis is the special product “PsoriControl”, which is available at a discounted price. Read the details in the official source.
- Description of the drug
- Compound
- Release form and characteristics
- For what diseases is it effective?
- Indications and contraindications
- Instructions for using the product
- Analogues and cost
A disease such as psoriasis has been causing unprecedented pain and discomfort to humans for many centuries. The reason for its appearance has not been fully studied.
Modern medicine offers many options for treating and eliminating the manifestations of this disease.
Among the variety of these drugs that have appeared in Russia, one can highlight the drug “Stelara”, which is available in the form of injections.
Consider in detail the characteristics and properties of this medicine, as well as the instructions for its use.
Description of the drug
Stelara injections for psoriasis and psoriatic arthritis belong to the group of immunosuppressants that have a depressing effect on the human immune system.
The use of this drug leads to a significant reduction in the histological manifestations of any form of psoriasis.
The drug “Stelara” is a monoclonal antibody for the treatment of psoriasis, which was obtained as a result of laboratory experiments. Despite its artificial origin, the drug is an absolute analogue of similar antibodies produced in the human body.
The basis of the action of this remedy is to have a significant inhibitory effect on the proteins that are responsible for the active growth and division of skin cells.
Along with this property, the drug “Stelara” has a pronounced anti-inflammatory effect.
Compound
One syringe (0.5 ml) contains the following components:
- active ingredient - ustekinumab;
- The auxiliary components of the drug are sucrose, polysorbate, water for injection, L-histidine.
The country of production of the drug “Stelara” is Switzerland.
Release form and characteristics
The drug for psoriasis and psoriatic arthritis, Stelara, is available in the form of a solution for subcutaneous administration. The colorless or light yellow solution is contained in special syringes.
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Stelara injections for psoriasis and psoriatic arthritis have an immunosuppressive effect on the body, inhibiting the influence of two main proteins that are responsible for the trigger of uncontrolled and chaotic division of skin cells.
These properties of the drug make it highly effective in the treatment of psoriasis, eliminating its skin manifestations.
After the first injection, a person can feel significant relief. Inflammation, itching disappears, and excessive peeling is eliminated.
The advantage of this remedy is that it has a direct effect on histological processes in the body, and does not simply relieve the characteristic symptoms of psoriasis.
The drug must be stored in a dark place out of reach of children.
The optimal temperature for storage is from +2 to +9 degrees.
Freezing the product is strictly contraindicated.
The shelf life is 2 years from the date of manufacture. Using the product after the expiration date is strictly prohibited.
For what diseases is it effective?
The medicinal effect of this drug applies mainly to severe psoriasis, as well as any of its manifestations. Also, the drug “Stelara” is effective for psoriatic arthritis in the acute phase.
In the first and second cases, the drug is used as a subcutaneous injection.
Indications and contraindications
Like any medicine, Stelara injections for psoriasis and psoriatic arthritis have their own indications and contraindications.
The main indications include:
- severe and moderate plaque form of psoriasis in persons over 18 years of age;
- psoriatic arthritis (as part of combination therapy), in persons over 18 years of age.
The main contraindications include:
- exacerbation of infectious diseases;
- age under 18 years;
- the presence of individual sensitivity to the components of the drug;
- the presence of a malignant tumor in the body.
During the studies conducted, no data on a possible overdose were obtained.
The drug is well tolerated by the body even if the dosage is increased.
If side effects occur, you should stop using the drug and begin symptomatic therapy.
The use of Stelara for the treatment of psoriasis is strictly contraindicated in children and adolescents under 18 years of age.
Such injections for psoriasis are not recommended for use by women during pregnancy and breastfeeding.
Instructions for using the product
To perform a subcutaneous injection for psoriasis, use the following instructions for use:
- remove the syringe with the medicinal component from the package;
- treat the injection site with an antiseptic;
- remove the protective cap from the syringe;
- form a skin fold at the injection site;
- insert the needle of the syringe and slowly press on the piston, while injecting the medicine;
- After the procedure, the injection site should be treated with an antiseptic.
The drug is injected into the upper thigh area, or into the area 5 cm below the navel. It is acceptable to use the area of the shoulder and buttocks.
For psoriasis, the dosage is 45 mg. The second injection should be carried out one month after the first injection. If the patient's weight exceeds 100 kg, then the recommended dosage is 90 mg of the drug. For the treatment of psoriatic arthritis, the dosage is also 45 mg.
This drug is not recommended for use in combination with other immunosuppressants, or in combination with antiviral vaccines.
Analogues and cost
In terms of its mechanism of action, as well as its degree of effectiveness, Stelara has no analogues.
The price for this product is quite high, about 235,000 rubles. per injection (45 mg). You can find out more about the price of this drug and buy it here apteka.hk/stelara.
Despite the price of this drug, its high effectiveness has been proven by many people suffering from all forms of psoriasis and psoriatic arthritis. For more detailed information regarding this drug, consult your doctor.
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Stelara - contraindications according to instructions
Like other medications, Stelara has a certain list of contraindications. If the patient has any condition from the list, the use of injections is prohibited.
- Stelara for psoriasis is prohibited for use as part of therapy intended for the treatment of children and adolescents under 18 years of age;
- Do not use the medicine during pregnancy in any trimester or while breastfeeding;
- Malignant tumors;
- Tuberculosis diseases;
- Exacerbation of chronic, infectious diseases;
- The drug should not be used for treatment in cases where the patient has an individual intolerance to any of the components of the drug.
The decision to prescribe a drug for treatment should be made by a dermatologist. In this case, the patient’s condition and the presence of individual reactions to any substances will be taken into account.
Indications for use
Indications for the use of Stelara serum may include various forms of psoriasis in children and adults. It is worth noting that this drug is used only for severe, acute forms of psoriasis.
Types of psoriasis:
- plaque psoriasis . Injections are prescribed if the disease progresses and no positive results are observed from other methods of therapy. Children with this diagnosis are treated with Stelara only from the age of 12 years;
- psoriatic arthritis . Prescribed only to patients over 18 years of age. The drug is prescribed as monotherapy or as part of a combination treatment with methotrexate.
Note! The effect of Stelar injections on children under 12 years of age and people with kidney and liver problems has not yet been well studied.
Stelara - instructions for preparing injections
The right attitude towards treatment is the key to success. When preparing injections, you must follow some rules. Before making appointments, you need to review the contraindications. The drug is prescribed with caution for the treatment of elderly people or in cases where there is a high tendency to relapse of diseases of parasitic-infectious origin. Special control should be placed on the condition of those patients whose body is trying to cope with damage from bacteria, viruses or fungi.
When preparing Stelara injections, you must adhere to the instructions for use. A single dose of medication is 45 mg. After the first injection has been given, you need to count down four weeks - then you can do the next injection of the drug. After this, injections are given every 12 weeks. If the patient is overweight, weighing more than 100 kg, the dose for treatment will be doubled - 90 mg.
The medicine is available in the form of an injection solution placed in special syringes for single use. Do not shake the instrument containing the medicine inside - if this has been done, the syringe must be disposed of. Injections are carried out as follows:
- The syringe containing the medication is removed from the cell. It is necessary to carefully check it for integrity. In this case, the syringe should be held in such a direction that the needle is turned away from the specialist who is about to give the injection.
- The injection area is treated using a cotton swab, which must be moistened in advance in an antiseptic solution.
- The protective cap must be removed from the needle. Sometimes you can notice an air bubble in the chamber with the medicine, and a drop of liquid at the end of the needle. The instructions for the drug Stelara allow the procedure to be carried out under such factors.
- An area of disinfected skin must be squeezed between the thumb and index finger, and the needle is inserted into the skin fold thus formed. Press the plunger slowly when injecting the medicine. When the syringe chamber is empty, the skin must be released and the needle carefully pulled out. If you then remove the finger from the piston, the needle itself goes inside the body.
- A fresh swab with an antiseptic is applied to the injection site for a few seconds. There is no need to rub the injection area. You can cover it with a band-aid.
- The syringe must be disposed of after use.
If a double dosage of Stelara is prescribed, use two syringes one after the other. In this case, the second injection should be carried out immediately after the first, but choose a different area or even a different area of the body for it. It is recommended to inject the medicine into the upper thigh, abdomen, buttocks, and shoulders. The selected area should not be covered with psoriasis rashes.
The first injections of ustekinumab must be carried out in a medical facility under the supervision of specialists. Subsequent injections can be performed independently, at home, if the attending physician does not object. The injections should be administered by a specialist familiar with the technique of subcutaneous injections.
It is up to the doctor to decide whether to stop taking the medication. In normal situations, a course of five injections of the drug, each after twelve weeks, is sufficient. This allows you to achieve remission for several years in advance.
Treatment with Stelara serum
The serum is injected subcutaneously using a syringe. Before administering the medicine, the injection site must be treated with an antiseptic. Next, remove the syringe with the medicine from the package, remove the needle from the cap and insert it into the treated area of skin, having previously folded it into a fold. The serum should be injected slowly, and then treat the area with an antiseptic.
Typically, the upper thigh area or the area under the navel, at a distance of 5 cm, is used to inject psoriasis serum. You can also inject into the shoulder or buttocks.
The serum is administered once a month, the duration of such treatment is determined by the doctor based on the results of monthly therapy.
Note! Patients whose weight exceeds 100 kg are given a double dose of the medicine.
Injections for psoriasis Stelara, price, composition
The pharmacological action of the drug Stelara and the effectiveness produced during treatment have no analogues. The effects of drugs belonging to the category of immunosuppressants are a little similar to it in action. Such, for example, is the drug Remicade based on infliximab, which is also a monoclonal antibody, or Humira based on adalimumab. Compared to the drug Stelara, analogues are cheaper, but their effect is lower.
If there is a need to replace the drug Stelara with another, the decision on the advisability of this should be made by the attending physician. The price of the medicine Stelara in Russia is quite high - you will have to pay 170 thousand rubles for one injection. In Moscow pharmacies the cost can reach up to 250 thousand rubles. Therefore, not everyone has the opportunity to use a unique action product. But it’s still difficult to call it unclaimed.
Stelara - reviews for psoriasis
The drug Stelara receives reviews quite regularly. It not only allows you to get the desired result in a short time, but also makes it possible to completely forget about the disease for many years. Many hope that the development of modern pharmacology will soon make the drug more affordable.
Irina, 34 years old: “I’ve been treated with Stelara for a long time, I’ve already had three injections. She did not note any side effects, and in the second week after the injection she noted a sharp improvement in her health. Very quickly the spots began to disappear from the skin. I don’t know what to say about remission yet.”
Anton, 42 years old: “It’s already been two years since I forgot about the torment due to psoriasis - after treatment with Stelar. I paid a lot of money, to be honest, I had doubts, but all my expenses were justified. The doctor warned that the disease tends to return, but now I know the right remedy against it.”
Ivan, 28 years old: “Stelara is a medicine that is as expensive as it is effective. Two years have passed since the course of treatment, and I don’t even remember how much discomfort psoriasis causes. It took me five injections to get the effect. “Before this, no drug could provide remission of the same duration.”
