"Ketotifen": instructions, analogues, contraindications

The drug Ketotifen is an excellent remedy for children's allergies and is an inexpensive and effective drug. It stabilizes the shell of mast cells itself, thereby reducing the amount of substances they secrete, namely leukotrienes and histamine. Also, the presented medicine prevents a large accumulation of eosinophils, in other words, cells responsible for allergies in a number of internal organs.

Adverse reactions to food products have several causes, and only some of them have an allergic basis. There may be various lines of reactions with an immunological mechanism in which the immune system has intervened, especially with the formation of antibodies and non-immunological reactions.

Thus, due to this type of motivation, diets are almost always addressed and maintained, despite the lack of convincing evidence of the alleged intolerance and despite the fact that dietary restrictions do not lead to any changes in symptoms. First of all, they make them overly protective of him, giving him a feeling of fragility and instability that can have a profound effect on his personality and forever. It is therefore appropriate to pose some specific questions on this issue.

The key active ingredient of the drug is Ketotifen fumarate. The medication is produced as syrup, special drops or tablets; upon purchase, you will need a doctor's prescription. It is good for 3 years when stored at temperatures up to 25 degrees. The tablets contain 1 mg of the active substance (exactly the same amount in the syrup), plus lactose monohydrate, starch, and tablet coating substances. Less Ketotifen fumarate is present in drops - only 0.25 ml, they also contain: benzalkonium chloride, NaCl, Trilon B, distilled water, dextran, sodium hydroxide, citric acid. Let's take a closer look at why and to whom Ketotifen is prescribed in different dosage forms.

Ketotifen tablets, instructions for use

With a delay, when the mechanism in its core is usually the activation of cells.
Classification of hypersensitivity hypersensitivity reactions. Be careful after taking responsible nutrition. In this case, it is usually very easy to understand the cause-and-effect relationship between food intake and subsequent symptoms. b. chronic, meaning they may develop slowly over several weeks or months. In this case, it is easy to fall into interpretation errors and exceed the diagnosis. Immediate hypersensitivity with gastrointestinal symptoms. In this regard, it is important to emphasize that such a reaction is immediately immediate, i.e. it must occur immediately after eating and in any case, by agreement, within two hours. In addition, although they are somewhat dependent on the amount of substance ingested, especially to determine the severity of the symptom, these are phenomena that can also be caused by minimal contamination and that occur mainly with every contact with food.

What patients and doctors say

Reviews from those who have used Ketotifen eye drops and from doctors help to understand how effective this remedy is.
“I am a chronic allergy sufferer. With the onset of spring, I am faced with a full list of allergic manifestations - my eyes turn red, I have a constant cough and copious amounts of mucus from my nose. For a long time I was looking for eye drops that could be combined with antihistamine tablets and cold remedies. Ketotifen is the only drug that helps me without any side effects” Artem Petrovich, 44 years old

“At the beginning of summer, when everyone is enjoying the warmth and the blooming greenery, I suffer from attacks of allergy to pollen. Unpleasant symptoms in my case are difficulty breathing and pain and itching in the eyes. For several years I have been unsuccessfully searching for a product that would simultaneously ease breathing and relieve redness and itching of the eyes. A doctor I know advised me to combine Ketotifen in the form of eye drops and tablets to relieve asthma symptoms. After using them, I was surprised to find that both my eyes and breathing returned to normal, now I always carry these medications in my bag." Anton, 29 years old

“When I came of age, during the flowering of the birches, I developed allergic conjunctivitis. The first two years the symptoms were mild, so I did not attach any importance to it. But last spring my eyes were constantly red, and I was forced to see a doctor. After an examination at the district hospital, the ophthalmologist prescribed me to instill one drop of Ketotifen into my eyes in the morning and evening. After two days of treatment, the redness subsided. Now, during the flowering period of birch trees, I will use this drug” Alisa, 22 years old

“In my more than 20 years of medical practice, I have used Ketotifen to treat allergic conjunctivitis, rhinitis and seasonal or chronic conjunctivitis. This medicine has established itself as a reliable remedy with minimal side effects" Sergey Pavlovich, ophthalmologist

“I am prescribing this medicine for the treatment of various allergic diseases. The drug shows almost 100% successful action. There are very few people whom it does not help or helps but not effectively enough. The dosage form in the form of syrup can be conveniently given to children, and the low cost of Ketotifen allows it to be prescribed to all segments of the population." Zinaida Petrovna, therapist

Contraindications for use

The product is instilled into the conjunctival sac, slightly pulling the lower eyelid down. The drop should be applied to the inner corner of the eye so that the substance is distributed throughout the mucous membrane with the flow of tear fluid. The medicine is not intended for other methods of administration.

The dosage of the drug is one drop in each eye twice a day. It is advisable to maintain an interval between drug administrations of 12 hours. The drop should be applied to each eye, even if manifestations of the disease appear in only one.

Hypersensitivity to the components of the drug (not only the active substance, but also the auxiliary components) is possible.

Also, the drug is not recommended for patients who cannot tolerate eye drops due to neurological pathologies (in this case, it is better to prefer Ketotifen tablets or syrup).

Overdose and special instructions

If you take the drug in excess, the following are possible:

• disorientation in space, dizziness;
• confusion;
• drowsiness;
• shortness of breath, heart rhythm disturbances;
• cyanosis;
• nausea, vomiting;
• decreased blood pressure;
• convulsions;
• coma.

To eliminate negative symptoms, you need to rinse your stomach. If the remedy was taken more than an hour ago, this method will not help. It is necessary to take sorbents that will remove excess active substances from the body. This could be Polysorb, Sorbex, Enterosgel, Polyphepan, etc. It is best to give Smecta to children.

When taken simultaneously, the effect of antihistamines and sleeping pills is enhanced. Ketotifen should not be taken with alcohol. If a sedative effect is observed, the drug is prescribed in small doses in the first two weeks. If you are taking bronchodilators, your doctor may recommend reducing the dosage of these medications. If there is steroid dependence, a possible complication is adrenal insufficiency. When combined with antidiabetic drugs, thrombocytopenia may develop.

The syrup contains a certain amount of excipients - methyl and propyl parahydroxybenzoates, which can cause urticaria

People with fructose intolerance should also use the syrup with caution, as it contains sorbitol.

Important instructions

Patients with contact lenses should be careful; the constituent substance of the drops can damage them.
Treatment with drops requires the following rules to be observed:

1. Before instillation, remove contact lenses. Ketotifen contains benzalkonium chloride, which can damage lenses. You can put them on 15 – 20 minutes after the procedure.
2. Drops cause drowsiness and decreased vision. You cannot drive or do work that requires concentration and increased attention.
3. Keep Ketotifen out of the reach of children, in the shade, at a temperature of 25 °C. Shelf life – 3 years. After opening the bottle, the drops must be used within a month.

special instructions

Persons with diabetes mellitus who take hypoglycemic drugs while using Ketotifen tablets should periodically monitor the level of platelets in the blood.

Patients who have recently been treated with beta-blockers or glucocorticosteroids should take Ketotifen tablets with caution, and especially with caution when discontinuing therapy. Abrupt withdrawal of treatment can provoke relapse of the disease and attacks of atopic bronchial asthma

Since the drug affects the functioning of the central nervous system and causes drowsiness in patients, during the period of therapy you should refrain from driving a car or operating complex devices that require increased concentration.

Patients who are highly sensitive to the effects of sedatives are prescribed a lower dose of the drug, which can be gradually increased over 14 days. This medicine is not intended to relieve an attack of bronchial asthma.

When is Ketotifen prescribed?

Ketotifen eye drops are prescribed for allergic diseases that are accompanied by conjunctivitis. These can be either seasonal or non-seasonal conditions that arise from contact with allergens. It may also be prescribed for non-allergic conjunctivitis, caused by an overreaction of the immune system to viral and bacterial infections of the nasopharynx and middle ear, which manifest as conjunctivitis.

Eye drops also have a beneficial effect in allergic rhinitis. For bronchial asthma, Ketotifen is prescribed in other dosage forms - tablets or syrup.

Can it be used by pregnant women and children?

The use of Ketotifen during pregnancy requires extreme caution. In the first trimester the drug is completely contraindicated

At later stages, it is prescribed only if the benefit to the mother is greater than the risk to the fetus. The drug is allowed during lactation. It can be used by children from the age of three.

Polynadim is completely contraindicated for pregnant and lactating women; children are allowed from 6 years of age as prescribed by a doctor.

Visin Allergy is allowed to be used at any stage of pregnancy under the supervision of a physician. Children are allowed from six months under the supervision of a pediatrician.

Lecrolin is allowed in the second and third trimester of pregnancy, but not recommended in the first. During lactation, it is prescribed only if the benefit for the mother is higher than the risk for the child, and it is advisable to interrupt lactation. It is prescribed to children from 3 years of age.

If it is necessary to use tablets during lactation, breastfeeding should be discontinued.

At the age of one to three years, the drug is prescribed in the form of syrup at a dose of 0.25 ml per kg of the child’s weight twice a day. Children over 3 years old are prescribed to take 5 ml of syrup or 1 tablet in the morning and evening.

The effectiveness and safety of the drug in children under 3 years of age have not been studied, so it should not be prescribed to patients in this age category.

Side effects of Ketotifen

Depending on the route of entry of the drug into the body, side effects may occur. When taken orally, the following are possible:

• slow and inhibited reactions, feeling tired, drowsiness, headache, sedation, dizziness, agitation, irritability, nervousness, sleep disturbance;
• dry mouth, pain in the epigastric region, increased appetite, nausea, vomiting, constipation;
• Stevens-Johnson syndrome, skin rashes, erythema multiforme, severe skin reactions;
• hepatitis, jaundice, increased levels of liver enzymes;
• dysuria, cystitis.

During treatment, both local and general side effects may occur. These include:

• conjunctival hyperemia, conjunctivitis, allergic reactions, headache, eye pain, dry mucous membrane of the eye, burning eyes, eye discharge, eyelid disorders, keratitis, impaired lacrimation, mydriasis, photophobia;
• rhinitis, flu-like syndrome, pharyngitis.

Overdose may cause hypotension, dizziness, drowsiness, vomiting, nausea, and convulsions in children. In this case, it is necessary to take general measures to eliminate the unabsorbed amount of the drug: induce vomiting by gastric lavage. If necessary, symptomatic treatment and monitoring of the cardiovascular and respiratory systems are indicated.

Side effects and contraindications

In general, Ketotifen is very well tolerated by the patient. Therapy with this medicine rarely leads to side effects, but you should still familiarize yourself with them before treatment. So, the patient may be concerned about:

• headache, dizziness;
• state of fatigue, increased drowsiness;
• the appearance of a sensation of a foreign body in the eye;
• nervousness;
• photophobia;
• the appearance of a rash (urticaria) on the eyelids;
• itching, tingling, burning in the eye area;
• visual impairment.

Many of the symptoms that appear may go away on their own, a few days after the first use. However, if unpleasant symptoms still bother the patient, he should consult his doctor.

It is important to know that drowsiness and fatigue are the most common side effects. If an ordinary person can lead a normal life, then for a person driving a vehicle or other mechanism that requires quick and correct response, this fact can lead to irreparable consequences

This must be taken into account by the attending physician when prescribing the drug. Usually the specialist replaces the drug with an analogue with fewer side effects such as drowsiness.

There are diagnoses and conditions in which the use of Ketotifen is contraindicated:

• pregnancy;
• lactation period;
• patient age – under 6 years;
• individual intolerance to the components of the drug.

Despite the fact that this drug has an antihistamine effect, in some cases it can itself cause an allergy attack in the patient. For this reason, it is necessary to first check the body's susceptibility. Also, the use of Ketotifen in persons with impaired liver function and convulsive disorders (including epilepsy) can only be prescribed under the strict supervision of a physician.

Indications

Use is contraindicated in the following cases:

• individual intolerance to substances and elements that make up the medicine;
• pregnancy and lactation phase;
• prescribed with caution to patients with renal and hepatic insufficiency, epilepsy;
• Children under 12 years of age.

A side effect is acceptable and can manifest itself as follows: burning and tingling sensation in the eyes, blurred, blurred vision after use, irritation of the ocular mucous membrane, allergic manifestations in the form of skin rashes around the eyes.

There have been no cases of overdose with Ketotifen eye drops.

Drops are prescribed by a doctor for acute forms of allergic conjunctivitis, keratoconjunctivitis, chronic conjunctivitis of an allergic nature, as well as for seasonal allergic conjunctivitis. Ketotifen eye drops are an effective remedy for helping patients with conjunctivitis. Widely used in ophthalmology to prevent allergies.

The tablets are intended for the treatment of allergic diseases: bronchial asthma, allergic bronchitis, hay fever, dermatitis, urticaria.

According to the instructions, the drug "Ketotifen" is prohibited from taking:

• When breastfeeding.
• Hypersensitivity to the composition of the drug "Ketotifen", from which these tablets can cause adverse reactions.
• Children under 3 years of age (tablets).
• During pregnancy (tablets).
• Babies up to six months (syrup).

Caution during therapy must be observed by pregnant women in the early stages when taking syrup, and by patients suffering from epilepsy and liver failure when taking tablets.

Indications for use recommend taking the drug for the prevention and treatment of allergies. The drug may be prescribed if the following symptoms develop:

• asthma, of any etiology and complexity;
• rhinitis, allergic etiology;
• hives;

Taking Ketotifen is contraindicated in the following cases:

• It is not recommended to take the drug if you are hypersensitive to Ketotifen and its components;
• direct contraindications for prescribing an antihistamine exist during pregnancy and while breastfeeding a child;
• Ketotifen is prescribed with caution to patients with chronic liver and kidney diseases, as well as if the patient has a history of epilepsy.

READ MORE: Azapentacene eye drops (with sodium polysulfonate), instructions

You should not prescribe a medication if its use causes pronounced side effects. If it is impossible to use Ketotifen, its analogues are prescribed.

The drug also has a number of contraindications for use, so before taking the tablets orally, you should carefully read the accompanying instructions. The medicine is not prescribed to patients with the following conditions:

• Children's age up to 3 years.
• Individual intolerance.
• Pregnancy.
• The period of breastfeeding a child.

The tablets should be used with caution in persons with liver disease accompanied by impaired liver function, and in patients with epilepsy.

Ketotifen is indicated for the following diseases:

• allergic and vasomotor rhinitis;
• asthma with an allergic component;
• allergic bronchitis;
• atopic dermatitis;
• hives;
• allergic conjunctivitis;
• hay fever;
• allergic dermatitis.

A child under 3 years of age can take the drug only in syrup form. In case of Quincke's edema, it is not advisable to prescribe it as an emergency remedy, since the effect does not occur instantly, and help is needed immediately - in order to avoid suffocation due to edema.

Treatment and prevention of allergic conjunctivitis.

Hypersensitivity to ketotifen or other components of the drug.

Interaction with other drugs and other types of interactions.

With the simultaneous use of ketotifen and antihistamines, a potentiation effect is possible.

Concomitant use with oral hypoglycemic drugs increases the possibility of developing thrombocytopenia.

If necessary, the drug can be combined with other eye drops. In this case, the break between instillations should be at least 5 minutes.

Possible interaction with antidepressants and alcohol cannot be excluded.

Drops are prescribed by a doctor for acute forms of allergic conjunctivitis, keratoconjunctivitis, chronic conjunctivitis of an allergic nature, as well as for seasonal allergic conjunctivitis. Ketotifen eye drops are an effective remedy for helping patients with conjunctivitis. Widely used in ophthalmology to prevent allergies.

The tablets are intended for the treatment of allergic diseases: bronchial asthma, allergic bronchitis, hay fever, dermatitis, urticaria.

If you are allergic to one of the components. It is also not recommended to exchange it for pregnant women and during lactation. Since the components of the drug can be passed on to the child. It is forbidden to use it in children under six years of age.

Drops should be prescribed with extreme caution in cases where a person has liver failure, epilepsy and seizures.

Ketotifen. Instructions for use

Ketotifen belongs to the latest generation of allergy medications. The problem of choosing the right one has worried more and more people in recent years.

If fifty years ago people suffering from allergies were rather an exception in society, their problems were understood by few people, but now a third of the patients who go to the doctor suffer from allergies.

On numerous forums, people ask questions, share their experiences, look for suitable medications and ways to relieve suffering.

It is especially difficult to realize how often allergy symptoms affect children, and from a very young age.

Immunologists and allergists are developing new drugs, eliminating the shortcomings of the previous ones. This is how a new generation of antihistamines are born, which do not have side effects such as apathy, harmful effects on the liver and heart, addiction to the drug, and others.

These new, improved drugs include Ketotifen.

Pharmacological characteristics of Ketotifen

As an antihistamine, Ketotifen blocks the effects of allergic pathogens at the cellular level and stops the migration of inflammatory cells, suppressing the reaction to the allergen. The drug is almost completely absorbed, bioavailability is more than 50%.

In what cases is Ketotifen prescribed?

• seasonal or year-round, conjunctivitis,;
• symptoms of bronchial asthma;
• with long-term chronic bronchitis with an asthmatic component;
• caused by allergies, urticaria, psoriasis;
• insect bites that cause an allergic reaction.

Although Ketotifen is freely available in pharmacies, it is better to consult a doctor before using it.

The drug is available in the form of syrup.

Ketotifen tablets are best taken during or after meals. Tablets are prescribed to children starting from the age of three.

Ketotifen tablets are small, smooth, and do not have a bitter aftertaste, so babies usually do not have problems with swallowing.

Children over 3 years old are usually prescribed one tablet twice a day (the doctor may adjust the dosage).

In the first days of treatment, drowsiness and fatigue are possible, so try not to plan important activities with your child during these days. Typically, these symptoms disappear after a few days.

Ketotifen syrup is sold together with a measuring spoon or measuring cup, their capacity is 5 ml of syrup.

The syrup tastes good and does not need to be diluted with water. Take with meals. If your child is allergic to fructose, talk to your doctor before taking this drug.

Children from 6 months to 3 years are usually prescribed half a measuring spoon (2.5 ml) twice a day, morning and evening.

Children over 3 years old – one spoon of syrup (5 ml) twice a day.

Ketotifen gradually accumulates in the body, so that the effect of treatment begins to be most evident after 48 hours.

This drug usually requires long-term (several weeks to several months) treatment. Also, doctors do not recommend sudden cessation of treatment; they often advise gradually reducing the dose and gradually exiting therapy.

Ketotifen (Zaditen)

pages:

Table of analogues and prices

Ketotifen - instructions for use (abstract)

There are contraindications. Before starting use, consult your doctor.

Commercial names abroad – Zaditor, Alaway, Zyrtec Itchy-Eye Drops, Claritin Eye

All antihistamines and mast cell membrane stabilizers here.

or publish a review about the medicine (please, do not forget to indicate the name of the drug in the text of the message) here.

Preparations containing Ketotifen (ATC code R06AX17):

Frequently encountered release forms (more than 100 offers in Moscow pharmacies) Rarely encountered and discontinued release forms (less than 100 offers in Moscow pharmacies)

Which generic is better?

Where can I buy?

Clinical and pharmacological group:

Mast cell membrane stabilizer. Antiallergic drug

pharmachologic effect

Stabilizer of mast cell membranes, has moderate H1-histamine-blocking activity, inhibits the release of histamine, leukotrienes from basophils and neutrophils, reduces the accumulation of eosinophils in the respiratory tract and the reaction to histamine, suppresses early and late asthmatic reactions to the allergen. Prevents the development of bronchospasm, does not have a bronchodilator effect. Inhibits phosphodiesterase, resulting in an increase in cAMP content in adipose tissue cells.

The therapeutic effect is fully manifested after 1.5-2 months from the start of therapy.

Pharmacokinetics

Absorption is almost complete, bioavailability is about 50% (due to the presence of the “first pass” effect through the liver). Time to reach Cmax is 2-4 hours, binding to plasma proteins is 75%.

Passes through the blood-brain barrier. Passes into breast milk.

Metabolized in the liver. It is excreted by the kidneys in the form of metabolites (the main metabolite, ketotifen N-glucuronide, is pharmacologically inactive). Within 48 hours, the bulk of the dose taken is excreted by the kidneys (1% unchanged and 60-70% in the form of metabolites). Elimination is two-phase: T1/2 of the first phase is 3-5 hours, the second is 21 hours.

Pharmacokinetics in children over 3 years of age does not differ from adults.

Indications for use of the drug KETOTIFEN

• atopic bronchial asthma;
• hay fever (hay fever);
• allergic rhinitis;
• allergic conjunctivitis;
• atopic dermatitis;
• hives.

Dosage regimen

Orally, during meals, adults – 1 mg (one tablet or one measuring spoon of syrup) 2 times a day in the morning and evening. If necessary, the dose is increased to 2 mg (two tablets or two measuring spoons of syrup) 2 times a day.

Children aged 3 years and older – 1 mg (one tablet or one scoop of syrup) 2 times a day.

Duration of treatment – ​​at least 3 months. Cancellation of therapy is carried out gradually, over 2-4 weeks.

Side effect

From the nervous system: drowsiness, dizziness, slow reaction speed (disappear after a few days of therapy), sedation, feeling of fatigue; rarely - anxiety, sleep disturbances, nervousness (especially in children).

From the digestive system: dry mouth, increased appetite, nausea, vomiting, gastralgia, constipation.

Urinary disorders: dysuria, cystitis.

Other: thrombocytopenia, weight gain, allergic skin reactions.

Contraindications to the use of the drug KETOTIFEN

• pregnancy;
• lactation period;
• children under 3 years of age;
• hypersensitivity.

With caution - epilepsy, liver failure.

Use for liver dysfunction

With caution - liver failure

special instructions

Abrupt cancellation of previous treatment with beta-adrenergic stimulants, glucocorticosteroids, adrenocorticotropic hormone (ACTH) in patients with bronchial asthma and bronchospastic syndrome after joining ketotifen therapy is undesirable; cancellation is carried out for at least 2 weeks, gradually reducing the dose. Treatment is stopped gradually, over 2-4 weeks (relapse of asthmatic symptoms is possible).

For persons sensitive to sedative effects, the drug is prescribed in small doses in the first 2 weeks.

Not intended to relieve an attack of bronchial asthma.

In patients concomitantly receiving oral hypoglycemic agents, the platelet count in the peripheral blood should be monitored.

Impact on the ability to drive vehicles and operate machinery

During the treatment period, it is necessary to refrain from driving vehicles and engaging in potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Overdose

Symptoms: drowsiness, confusion, disorientation, bradycardia or tachycardia, decreased blood pressure, shortness of breath, cyanosis, convulsions, increased excitability, coma.

Treatment: gastric lavage (if a little time has passed since administration), symptomatic treatment, with the development of convulsive syndrome - barbiturates or benzodiazepines. Dialysis is ineffective.

Drug interactions

Strengthens the effect of sleeping pills, antihistamines, ethanol.

In combination with hypoglycemic drugs, the likelihood of developing thrombocytopenia increases.

Conditions for dispensing from pharmacies

The drug is available with a prescription.

Storage conditions and periods

List B. Store out of reach of children, in a dry place, protected from light at a temperature not exceeding 25°C. Shelf life – 3 years.

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Analogues of the drug Ketotifen

The French "Zaditen" and the Latvian "Histafen" are the closest medicinal products to the one in question. They have a similar pharmacological antihistamine effect. However, their price is significantly higher.

The following medicinal products also have antiallergic properties similar to Ketotifen: Claritin, Erius, Cetrin, Loratadine, Zyrtec. The price of the listed medications is also slightly higher than the cost of Ketotifen eye drops.

The drug is prescribed for therapy:

• Allergic conjunctivitis.
• Atopic dermatitis.
• Bronchial asthma of atopic nature.
• Bronchitis.
• Urticaria.
• Hay fever.
• Rhinitis and other manifestations of allergies.

How to take pills

Doctors can prescribe the following analogues of the drug:

1. "Ketotif."
2. "Katifen."
3. "Broniten."
4. "Zerosma."
5. "Denerel."
6. "Ketasma."
7. "Ketotifen-Rivopharm".
8. "Profilar".
9. "Astafen."
10. "Tofen."
11. "Ketotifen-Ros".
12. "Positan".
13. "Ketotifen Stada".
14. Zetifen.
15. "Frenasma."
16. "Staffen."
17. "Ketotifen Sopharma".
18. "Trytofen."
19. "Ketotifen Stada".
20. "Zaditen SRO."
21. "Irifen."
22. "Privant."
23. "Ketof".
24. "Zaditen."

The name of the drug completely coincides with the name of its active substance - ketotifen. This is an antiallergic drug that blocks the release of biologically active substances involved in the formation of an allergic reaction, primarily histamine. Its dosage in eye drops is 0.25 mg/ml.

In addition, the drug contains additional substances that facilitate its administration and distribution throughout the conjunctival sac.

The combination with alcohol is categorically undesirable - this significantly increases drowsiness, and the development of a convulsive attack is possible.

The drug is sold by prescription, its cost is from 200 rubles, depending on the city and pharmacy. Other dosage forms of Ketotifen are cheaper.

Can significantly enhance the effect of sleeping pills, as well as antihistamines and ethyl alcohol.

Analogues are determined by structure:

1. Frenasma.
2. Positan.
3. Zaditen SRO.
4. Zaditen.
5. Ketotifen Stada (Sopharma).
6. Staffen.
7. Ketof.

Manufacturers offer Ketotifen in the form of tablets, capsules, flavored syrup and eye drops. In children's practice, the syrup has a pleasant fruity taste and has proven itself well. The baby does not need to be persuaded to take the medicine for a long time; he drinks it with pleasure. The bottle contains 100 ml of syrup, 5 ml of which contains 1 mg of ketotifen.

Eye drops in 5 ml bottles are used only in ophthalmology for allergic conjunctivitis; their use is permitted for children over 12 years of age. There are analogues for younger children.

Ketotifen tablets of 1 mg of the active substance are packaged in contour foil cells of 10 tablets in quantities from 1 to 5 per package. Ketotifen capsules have a similar dosage. These release forms are applicable for children from the 4th year of life.

Eye drops.

Basic physical and chemical properties: transparent or slightly opalescent, colorless or slightly yellowish liquid.

Analogues of the allergy drug Ketotifen

Ketotifen is a drug that is used for various allergic manifestations. It is an antihistamine blocker, reduces asthmatic and allergic attacks. The method of use of this drug depends on the form of release.

Ketotifen has proven itself very well in the treatment of not only adult patients, but also children. In this article we will try to answer the question of whether this drug has analogues and whether there are more effective medications for allergies.

General information about the drug

This drug belongs to the group of anti-asthmatic drugs. Has anti-allergic and membrane-stabilizing effects. The main active ingredient is ketotifen fumarate.

The drug is available in various forms: tablets, capsules, syrup and eye drops. Their main differences are indications for use, dosage and amount of the active component included in the composition. Lactose, starch, and magnesium stearate may be present as excipients. The drops contain sodium hydroxide, dextran, Trilon B and other components.

The mechanism of action of Ketotifen is based on inhibition of the movement of calcium ions, reducing their number in mast cells (cells of the immune system), and blocking the spread of allergens.

During treatment, the patient's eosinophil content decreases (they are the ones that are activated during an allergic reaction) in the respiratory system.

The drug has an anti-asthmatic effect and stops bronchospasm.

The peak concentration of the active ingredient is recorded 2-3 hours after administration, and in the case of using eye drops - after 8-12 hours. Metabolism occurs in liver cells, the drug is excreted from the body mainly through urine (half-life is from 3 to 48 hours).

Depending on the form of release, the indications for the use of Ketotifen differ. Ketotifen in the form of tablets or capsules is prescribed for:

Ketotifen in the form of syrup is used mainly for pediatric patients, the main indications are:

• allergic rhinitis and conjunctivitis;
• complex treatment of asthma of an allergic nature;
• atopic dermatitis and urticaria.

Drops are used for allergic eye lesions. It is worth noting that this form is prescribed to patients from 12 years of age, the duration of the course should not exceed 6 months. Ketotifen in the form of eye drops is sold in pharmacies only with a doctor's prescription.

Contraindications include hypersensitivity to the components of the drug, pregnancy and breastfeeding.

Sometimes patients during treatment may experience the appearance of such unpleasant symptoms as:

• drowsiness;
• feeling of dryness in the mouth;
• dizziness and headache;
• intestinal disorders;
• seizures (especially for pediatric patients);
• irritability;
• liver dysfunction (very rare).

As a rule, these symptoms appear and disappear spontaneously. If they do not go away for a long time, then you need to stop taking Ketotifen and consult a doctor.

The instructions for use indicate that Ketotifen in tablet form should be taken before meals with a small amount of liquid. For adults and children over 12 years of age, 1 tablet is prescribed 2 times a day.

If increased sedation occurs, it is recommended to gradually increase the dosage over the course of a week, starting with 1/2 tablet. In this case, Ketotifen is taken once a day. It's best to do this before bed.

Thus, over 7 days increasing the amount to 2 mg per day.

The drug in syrup form is prescribed to children aged 12-36 months. The daily dosage is based on 0.25 mg for each kg of the child’s weight, divided into 2 equal doses (the time interval should be at least 8-12 hours). The permissible amount is no more than 10 ml of syrup. It can be mixed a little with water or breast milk.

Eye drops are prescribed to patients from 3 years of age. They must be instilled carefully into the conjunctival sac, 1 drop twice a day. The duration of treatment depends on the nature of the disease and can last quite a long time. The therapeutic effect appears only 14-21 days after the start of treatment. The average course is 60-90 days.

It is important to note that drug withdrawal is carried out gradually. This is done to reduce the risk of relapse.

The drug is sold by prescription; the average price of Ketotifen varies from 50 to 350 rubles, depending on the form and manufacturer.

Positive and negative properties

Among the advantages of using Ketotifen are:

• Possibility of use in children from the age of 12 months;
• affordability;
• rapid therapeutic effect;
• variety of release forms.

Despite the large number of advantages, the drug also has significant disadvantages:

• belongs to the group of antihistamine dosage forms of the old generation;
• lasting results occur with a long course of treatment;
• prohibited for use by pregnant and nursing mothers;
• has a large number of side effects, especially if the permissible dosage is exceeded.

Before starting to use this medicine, you should definitely consult with your doctor.

Analogs

Complete analogues of the active component are Ketof, Staffen and Frenasma. Other drugs in tablet form include Zaditen (also available in the form of eye drops) and Pozitan, their average cost is 300-400 rubles.

In the form of syrup, analogues of Ketotifen are Claritin, Zaditen, Edem, Erius. Their average price in pharmacies is in the range of 300-600 rubles. Only a doctor can decide on the advisability of replacing Ketotifen with another drug.

Comparison of Ketotifen with other antihistamines

Many patients often have a question: which drug is better: Ketotifen, Loratidine or Suprastin. As noted above, Ketotifen belongs to the old generation antihistamines. Today, doctors more often prescribe Loratidine or Suprastin.

They do not cause so many side effects and are allowed for use in infants. It is worth noting that Suprastin is also available in injection form, which is very important when a child’s body temperature rises significantly due to allergies. In this case, injections are performed with Analgin.

These drugs are much more expensive than Ketotifen, but their therapeutic effect occurs much faster. The disadvantage of Suprastin is that it should not be used in children under 36 months. It is allowed to take Ketotifen with Suprastin at the same time, but only according to a strict regimen prescribed by the attending physician.

antihistamines

Among the most effective drugs today are:

1. Cetrin . Available in tablet form. Does not cause drowsiness. The effect comes very quickly. The drug does not have a toxic effect on liver cells.
2. Claritin . Does not have a sedative effect. Can be used by people who drive vehicles. Prescribed for various forms of allergies.
3. Fenistil . Available in various forms: drops, tablets, ointment and gel. Can be used to treat adults and children. The drug belongs to the first generation antihistamines.
4. Histalog . It has a long-lasting therapeutic effect (up to 3 weeks). However, it is contraindicated for people suffering from diseases of the cardiovascular system.
5. Tavegil . Inexpensive, available in tablets and injections. Allowed for use in children from 12 months. The therapeutic effect occurs in a short time.
6. Suprastin . Available in tablet and injection form. It does not tend to accumulate in the patient’s blood. To prolong the effect, it must be combined with other antihistamines.
7. Diphenhydramine . Despite the fact that it belongs to the first generation of antiallergic drugs, it is still used today. The effect comes very quickly and lasts a short time. The drug causes drowsiness and a pronounced sedative effect.

Tavegil Claritin Fenistil Cetrin

Among the drugs with low cost are the following:

1. Diazolin . Its price starts from 60 rubles. Has the property of irritating the mucous membrane of the gastrointestinal tract.
2. Trexyl . Cost from 95 rub. Among the disadvantages is a pronounced depression of the cardiovascular system.
3. Cetirizine . Price - from 100 rubles. Used for various forms of skin dermatitis. Does not have the ability to accumulate in the body.
4. Desorus . It is considered one of the cheapest analogues of Ketotifen, the price is from 50 rubles.
5. Alerik . One of the cheap analogues of Loratidine, cost from 60 rubles.

Remember that you should not self-medicate, as this leads to serious complications. Taking the drug incorrectly can cause side effects.

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Source: https://allergia.life/lekarstva/ot-allergii/analogi-ketotifena.html

Analogs

There are some analogues of this drug, some are similar to it in composition, others in action, and there are also no few distinctive features.

List of analogues:

Suprastin. A drug that is not similar in composition to this medication. Many doctors and patients claim that Suprastin is the most effective allergy remedy among all existing ones. The action of Suprastin begins approximately an hour or an hour and a half after administration. The cost of the medicine varies from 90 to 150 rubles per package. Ketof. A drug that is very similar to this one. It differs in that it is allowed for children from the first month of life. Available in three forms: capsules, tablets and syrup for children, which is very convenient for many people. The price varies from 30 to 200 rubles per package. Zaditen. Released in the form of eye drops that fight conjunctivitis with a bang. The effect of the medication begins on the second day of use, and after 5 calendar days everything will go away completely. It has a very low price from 130 to 270 rubles per package of 5 ml drops. Zodak. The drug is released in three forms: drops, syrup and tablets. Drops are suitable for children from 18 months of age. It has a rapid onset of action, literally 45-80 minutes after ingestion. The medicine, although expensive, is very effective. The price varies from 170 to 500 rubles per package

It does not cause side effects, which is very important for most patients. Zyrtec. Allowed for children from 6 months, the main side effect of the medication is headache, which goes away immediately after finishing the course of taking the drug

It has a high cost of 200 to 400 rubles per package. The action begins an hour after administration and remains valid for 48 hours, which is very convenient, because you can forget about the drug for two days and not suffer from allergy symptoms.

If you want to cure allergies completely and the duration of treatment is not important to you, then this medication is best for you. Cheap, effective, without causing side effects - what many people need.

Pharmacological effect

The drug effectively inhibits the release of histamine and other mediators, and perfectly blocks histamine type H1 receptors. The medication inhibits the PDE enzyme.

Only with the use of Ketotifen alone, asthma attacks are not completely stopped. But it prevents their further occurrence and noticeably reduces the strength and length of attacks. Sometimes they stop completely. Within a couple of hours after administration, the highest concentration of Ketotifen is recorded in the blood. The majority of the dose is processed in the liver. About 70% of the drug is excreted through the urinary canal.

This condition affects about 6% of young children and tends to resolve spontaneously in most of them after the age of 3 years. In Italy, the foods most affected by this type of allergy are cow's milk and eggs, especially egg whites. Allergic enteropathic foods Ø Milk Ø Soy Ø hydrolyzed Ø gluten Ø peanut Ø egg Ø nut Ø Fish Ø Multiple food allergies. Real Symptoms of Food Allergies We see which symptoms would strongly justify a suspected food allergy according to the criteria considered valid by the Committee on Allergy of the American Academy of Pediatrics.

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What drugs can be considered analogues of “Ketotifen”

“Zaditen” refers to antihistamine medications. The active component of the drug is ketotifen. The medication perfectly relieves allergy symptoms. Zaditen is not capable of causing drowsiness. The drug does not have a negative effect on the condition of nerve endings.

The drug “Zaditen” is produced in the form of syrup, eye drops, and tablets. According to the instructions for use of the drops, the medicine is actively used in the treatment of allergic conjunctivitis. It should be noted that the drug is not recommended for use during lactation. The medicine can pass into breast milk.

The consistency of Zaditen eye drops is an odorless solution. They are colored yellowish. The medicine is packaged in a polyethylene bottle with a convenient dropper.

The advantage of Zaditen drops over medications intended for oral administration is the rapid onset of the desired effect. The average duration of treatment is one month.

Patients over twelve years of age should instill one drop of Zaditen into each eye. Frequency of use – twice a day.

When using Zaditen, the following side effects may occur:

• Decreased vision clarity;
• A feeling of dryness in the eyes;
• Hemorrhage;
• The appearance of pain in the eyes;
• Irritation on the body;
• Feeling of dry mouth;
• Fatigue.

There is no information about an overdose of Zaditen drops. If you accidentally use tablets or syrup in large quantities, the following complications may occur:

• Deterioration of orientation in space;
• Reduced blood pressure;
• Convulsions;
• Cardiopalmus.

There are many analogues of Ketotifen eye drops in terms of therapeutic effects. “Vizin Alergy” perfectly eliminates the signs of conjunctivitis of an allergic nature:

• Increased lacrimation;
• Itching;
• Swelling of the eyelids;
• Eye irritation.

The effect of Vizin Alergy lasts for up to ten hours. The medication should not be used if you are hypersensitive to its components. Visin Alergy is not used in the treatment of allergic conjunctivitis in patients under twelve years of age.

When drops are instilled into the eyes, the following side effects may occur:

• Nausea.
• Lethargy.
• A feeling of dryness in the eye area.
• Dizziness.
• The appearance of skin rashes.
• Increased lacrimation.

Visin Alergy should be instilled one drop into each eye twice a day. Treatment is continued until the main manifestations of the disease disappear.

If you mistakenly take a large dose of eye drops orally, complications such as a sharp decrease in blood pressure, an increase in heart rate, and severe weakness can occur.

Instructions

The duration of treatment directly depends on the severity and type of the disease. When the patient has chronic or subacute diseases, prophylactic use of the drug should begin approximately 3 weeks before contact with the allergen.

In this case, treatment should take place throughout the entire period of interaction with the allergen. Before starting therapy, you should definitely read the instructions for use included in the package with the medicine.

Use of the drug during pregnancy

This medicine is prohibited for use by pregnant women and while breastfeeding, because its components may adversely affect the newborn baby or fetus. To choose the right and safe medication, you should definitely consult your doctor.

READ MORE: Visomitin eye drops - instructions, price, reviews and analogues

It is important! This product is dispensed only with a doctor's prescription.

Effect on the body when used with other drugs

In the case of simultaneous use of Ketotifen and antihistamines, a synergistic effect (potentiation) is possible, that is, an increase in the healing properties of the products used.

Thrombocytopenia may develop when this medication is used concomitantly with an oral antidiabetic agent.

Additional usage features

It is acceptable to use drops in conjunction with corticosteroids during a sharp exacerbation of a chronic disease or acute inflammation. A mandatory warning is required from the attending physician about the regular use of the drug.

During treatment, when eye drops are used, soft contact lenses cannot be used, since their structure includes benzalkonium chloride. If the patient wears hard lenses, they must be removed before instillation into the eye. Such lenses are allowed to be inserted only after at least 15 minutes have passed after the procedure.

Work that requires high attention should be postponed for a certain period of time after instillation of the medicine.

proglaza.ru

Ketotifen instructions for use recommend using the drug at least twice a day, simultaneously with meals.

The release form includes syrup, capsules, tablets and eye drops.

Ketotifen should be taken starting from 0.5 mg at a time if the drug has a mild sedative effect on the patient. In cases where there are indications for increasing the dosage, it should be increased gradually. The maximum permissible dosage can be 4 mg, divided into 2 doses.

• Adult patients are prescribed 1 mg 2 times a day. If there are indications (urticaria, hay fever, etc.), the dosage can be increased to 2 mg;
• Ketotifen is prescribed to children under 6 months only in syrup -0.05 mg per 1 kg. body weight;
• indications for children from 6 months to 3 years recommend a dosage of 0.5 mg. 2 times during the day;
• from 3 years – 1 mg. 2 times a day;
• eye drops 0.025% are instilled into the conjunctiva - 1 drop 2 times a day;
• the duration of therapeutic treatment for allergies can reach 3 months, after which the dosage form can be changed;
• Treatment should be stopped gradually over 2-4 weeks. Asthma can be controlled with a double dosage, which is prescribed by the attending physician.

Ketotifen for young children is usually prescribed in syrup. Ketotifen syrup acts more gently. In this case, the tableted drug is used quite rarely.

The medicine should not be taken during pregnancy. It is prohibited to take the drug for breastfeeding women. To choose the most adequate treatment and appropriate dosage, you should consult your doctor. Especially if asthma or urticaria develops as a result of allergies.

The product is instilled into the conjunctival sac, slightly pulling the lower eyelid down. The drop should be applied to the inner corner of the eye so that the substance is distributed throughout the mucous membrane with the flow of tear fluid. The medicine is not intended for other methods of administration.

The dosage of the drug is one drop in each eye twice a day. It is advisable to maintain an interval between drug administrations of 12 hours. The drop should be applied to each eye, even if manifestations of the disease appear in only one.

The duration of treatment is until the symptoms of the pathology disappear. Can be combined with other allergy medications.

Hypersensitivity to the components of the drug (not only the active substance, but also the auxiliary components) is possible.

Also, the drug is not recommended for patients who cannot tolerate eye drops due to neurological pathologies (in this case, it is better to prefer Ketotifen tablets or syrup).

What does Ketotifen help with? Tablets according to the instructions are used to treat the following diseases:

• Allergic conjunctivitis.
• Allergic rhinitis.
• Atopic dermatitis.
• Atopic bronchial asthma.
• Hives.
• Seasonal allergic rhinoconjunctivitis (hay fever).

The drug in the form of syrup is taken to prevent the above and other allergic diseases, including allergic bronchitis.

Ketotifen tablets are taken orally with meals. Adults are prescribed 1 mg 2 times a day in the morning and evening. If necessary, the dose is increased to 2 mg 2 times a day.

Children aged 3 years and older are given 1 mg 2 times a day. The duration of treatment is at least 3 months. Cancellation of therapy is carried out gradually, over 2-4 weeks.

Syrup: taken orally in the morning and evening with meals. Dosage for adults and children aged:

• from 3 years – 1 mg (5 ml) 2 times a day;
• for children from 6 months to 3 years – 0.5 mg 2 times a day.

The daily dose for adults can be increased to 4 mg if necessary.

Starting from 3 years, you can instill one drop twice a day into the conjunctival sac.

Treatment with Ketotifen takes a long period. In this case, a noticeable effect after taking it will be achieved after 2-3 weeks of therapy. The general course of treatment can be two to three months. Those patients who did not experience any visible effect after several weeks of taking the medication should take this medication for a particularly long period.

Treatment with this drug is stopped gradually over several weeks. This is done to avoid recurrence of asthmatic symptoms.

Instructions for use of Ketotifen contain detailed instructions on the rules of administration. Additional or special treatment regimens will be developed by the attending physician. The use of Ketotifen in any form of release is indicated during meals.

READ MORE: Tablets for puffiness under the eyes: a review of popular drugs

The package insert contains information about the good absorption of the drug. Bioavailability is 50%, maximum concentration in the blood is achieved 2-4 hours after administration.

If before prescribing the drug the child was receiving glucocorticoids, ACTH or beta-agonists, then they should be discontinued gradually, reducing the dose over 2 weeks. The same rule applies to the withdrawal of Ketotifen. The instructions prescribe discontinuation of the drug gradually over 2-4 weeks. It should be remembered that Ketotifen, having undergone metabolism in the liver, is excreted by the kidneys in approximately 2 days in the form of a pharmacologically inactive metabolite.

The medicine is a transparent, slightly yellowish, aromatic liquid. The syrup is freely available in the pharmacy chain and is available without a prescription. The drug contains ethanol and flavoring additives (strawberry, banana). Dosage depends on age:

• Children from six months to 3 years old are given half a teaspoon of syrup with meals, 2 times a day;
• after 3 - 5 ml (1 tsp) 2 times a day.

Typically, the doctor prescribes a long course of treatment (at least 2 months) with a gradual dose reduction before discontinuation.

The syrup is given during meals, following a strict dosage calculation.
When instilling the drug, soft contact lenses should be removed due to possible absorption of the preservative (benzalkonium chloride) and not put on them earlier than 15 minutes after instillation.

All eye drops containing benzalkonium chloride (as a preservative) may possibly discolor soft contact lenses.

For adults and children over 3 years of age, it is recommended to instill 1 drop 2 times a day into the lower conjunctival sac.

The contents and dispenser of the bottle remain sterile upon opening the primary packaging. The patient should be instructed to avoid contact of the tip of the dispenser with the eye or adjacent tissues as this may contaminate the solution.

Eye drops are intended for adults and children over 12 years of age. The medicine should be instilled one drop into each eye twice a day.

The use of the drug for preventive purposes should begin three weeks before contact with the allergen and continue the course of treatment during the period of exposure to the allergen.

The duration of use depends on the severity of the disease.

Before starting treatment, you must carefully read the instructions in order to know how to take Ketotifen correctly. The medication is taken twice a day - morning and evening at a dosage of 1 mg. If necessary, after consulting a doctor, the dose is increased. When taking the medicine, an allergic reaction may occur. In such cases, it is necessary to interrupt treatment and inform the attending physician.

The duration of treatment with Ketotifen is three months. Discontinuation of the drug must be carried out gradually.

Release form

Analogues (6)

Where to treat

The drug is prescribed only to people over 12 years of age. Installation must be carried out one drop once a day. The effect of use occurs instantly and lasts for 8-12 hours.

Draw your attention to! If we are talking about seasonal allergies, then you should start using it several weeks before contact with the allergen. This will allow you to avoid all possible problems at the initial stage.

The drug should only be prescribed by a doctor, since it is he who can determine the actual dose. If the remedy does not help, then the dose is increased. But everything should be done only under the supervision of a doctor.

Always remove lenses 15 minutes beforehand. They should be put on after about 15-25 minutes, so that the product does not accidentally get on the lenses. It is recommended to avoid driving, as this may cause drowsiness. Keep out of reach of children. Do not smear the bottle pipette, this can cause infection.

special instructions

You should not stop previously prescribed treatment using glucocorticosteroids and beta-agonists. The withdrawal of medications is carried out within two to four weeks.

If a sedative effect occurs, the drug should be used in minimal doses.

If the course of treatment included polyglycemic drugs, it is necessary to laboratory monitor the number of platelets in the blood.

The therapeutic effect of Ketotifen appears after 4 to 8 weeks of use of the drug.

The use of Ketotifen during pregnancy is permitted only as prescribed by the attending physician if the use of the drug is necessary for the health of the mother. The dose of the drug during pregnancy is calculated individually.

During lactation, the use of Ketotifen is prohibited due to the high permeability of the drug into breast milk and the possibility of harming the baby.

Directions for use and doses

The product is instilled into the conjunctival sac, slightly pulling the lower eyelid down. The drop should be applied to the inner corner of the eye so that the substance is distributed throughout the mucous membrane with the flow of tear fluid. The medicine is not intended for other methods of administration.

The dosage of the drug is one drop in each eye twice a day. It is advisable to maintain an interval between drug administrations of 12 hours. The drop should be applied to each eye, even if manifestations of the disease appear in only one.

The duration of treatment is until the symptoms of the pathology disappear. Can be combined with other allergy medications.

Composition and release form

Transparent or slightly opalescent liquid with a pale yellow tint. One milliliter of dosage form (eye drops) contains 0.25 mg of active substance. Auxiliary components: non-alkonium chloride, sodium chloride, Trilon B, dry polyglucin, sodium hydroxide, citric acid, purified water.

The release form of eye drops is 5 ml bottles, in cardboard packaging. How to take Ketotifen correctly - instructions are attached.

Ketotifen tablets are white, shaped like a flat cylinder, and odorless. The composition contains the active component ketotifen fumirate in the amount of 0.00138 grams, which corresponds to one milligram of ketotifen.

Additional substances: magnesium stearate, calcium phosphate, potato starch.

Tablets of 10 and 20 pieces are produced in contour packaging with cells. The material used for packaging is polyvinyl chloride and lacquered aluminum foil. Available in one, two, three cell packs in packs of thick cardboard.

Ketotifen syrup is a viscous, transparent, colorless liquid with a characteristic strawberry odor. Five milliliters of syrup contains 1.38 mg of ketotifen hydrofumarate, which is equivalent to one milligram of ketotifen content.

Excipients: methyl parahydroxybenzoate, propyl parahydroxybenzoate, sorbitol, citric acid monohydrate, sodium hydrogen phosphate dodecahydrate, ethanol 96%, sodium saccharinate, strawberry flavor.

pharmachologic effect

A drug with a pronounced antiallergic effect, has an antiasthmatic effect and antihistamine properties. Suppresses the body's susceptibility to the effects of allergens, and also prevents their accumulation in the bronchi. Eliminates the development of increased bronchial reaction under the influence of allergens.

Once in the body, it is completely absorbed. Bioavailability (the amount of a drug reaching its site of action) is 50%. After two to four hours it reaches a high level in the blood plasma. As soon as the drug enters the eyes (eye drops), its therapeutic effect immediately appears, which lasts 8-12 hours. Metabolized in the liver. Time of elimination from the body is 48 hours.

Price

It is advisable to store the product in places well protected from sunlight, at an average air temperature of about 25°C. Shelf life is 3 years.

The produced form is vials of 10 or 5 ml with a sterile cap in the form of a dropper.

The price of the product may vary slightly, depending on the manufacturer. But the average cost for a medicine (10 ml volume) is 165-170 rubles.

Author of the article: Yuliy Samoilov

myallergy.ru

You can buy Ketotifen in Moscow and other Russian cities for 57-99 rubles. The price in Kyiv and Minsk reaches 9-30 hryvnia and 0.27-1 bel. rubles respectively. You can buy it in Kazakhstan for 420 tenge.

The average cost of Ketotifen (syrup 100 ml) in Moscow is 87 rubles. The price of tablets is 58 rubles. for 30 pcs. Dispensed with a prescription, belongs to list B.

It should be stored in a dry place, protected from light, out of reach of children, at a temperature not exceeding 25C. Shelf life: 3 years.

Ketotifen tablets cost from 50 to 75 rubles per pack of 30 pieces. 100 ml of Ketotifen syrup costs 80 rubles. Ketotifen eye drops are sold for 44 rubles. Analogues may cost a little more, but many of them can be purchased for 150-250 rubles.

There are no direct analogues of Ketotifen, but the list of drugs that are similar in their mechanism of action and therapeutic effect is extensive. The drugs closest to Ketotifen are:

• Daltifan (India);
• Zaditen (France, Switzerland);
• Ketotifen (Sopharma, Bulgaria).

The average price of Ketotifen eye drops in Russian pharmacies is 40-50 rubles. In Ukraine you can find this drug for 20-25 UAH.

The instructions for using Ketotifen eye drops indicate that it should be stored in a place inaccessible to the child, at room temperature. The shelf life is three years. Once opened, the drops can be stored for a month. The average cost of the substance is 100 rubles. It is cheap and therefore accessible to everyone. Price may vary depending on location of sale.