Allergy to vitamin D in infants: photos, symptoms, can there be a negative reaction in children?

What can cause an allergy to vitamin D?

Nursing mothers and infants need vitamin D more than others. In mothers, it supports the functioning of the thyroid gland, kidneys, and preserves teeth and hair. For babies, vitamin D prevents rickets and forms the skeleton (more details in the article: how is rickets prevented in infants?). Irrational, excessive intake of vitamins leads to allergies. Causes:

1. the presence in the diet of a nursing woman of drugs containing vitamin D3 (Vitrum Prenatal Forte, Pregnavit);
2. feeding infants with dry formulas, with which the child’s body receives 600 IU of vitamin D3, and for infants up to one year old it is enough to receive an average of 400 IU per day (1 IU = 1 mg);
3. receiving vitamin D by infants in the form of medications (Aquadetrim, Vigantol, Videhol) (we recommend reading: instructions for use of “Aquadetrim” for newborns).

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Interaction with other drugs

Oily solution for oral administration, packaged in a 10 ml bottle with a dropper.

Long-term use of Vigantol drops during treatment with antacid drugs containing magnesium and aluminum salts increases their level in the blood and the risk of intoxication, especially in patients suffering from renal failure.

Barbiturates, phenytoin and primidone increase the need for vitamin D3 due to an increase in the rate of biotransformation. Cholestyramine and colestipol reduce the absorption of fat-soluble vitamins from the digestive tract and require an increase in their dosage.

When prescribed simultaneously with glucocorticosteroids, calcitonin, bisphosphonates, plicamycins, the effectiveness of the drug may be reduced.

Vigantol increases the absorption of phosphorus-containing drugs and the likelihood of hyperphosphatemia.

When administered in parallel with sodium fluoride, the interval between doses should be at least 2 hours, with tetracyclines for oral administration - 3 hours.

When taken simultaneously with rifampicin and isoniazid, a decrease in the effect of the drug may be observed due to an increase in the metabolic rate.

When co-administered with benzodiazepine derivatives, the likelihood of increasing calcium levels in the blood increases.

With concomitant therapy with cardiac glycosides, the likelihood of developing a toxic effect from them, which is observed due to hypercalcemia, may increase. In such patients, concentration should be monitored. calcium, electrocardiogram and adjust the dosage of cardiac glycosides.

While taking thiazide diuretics, there may be a decrease in calcium excretion in the urine and an increased likelihood of developing hypercalcemia.

Vigantol can be prescribed simultaneously with vitamin D analogues only in extreme cases and under the control of calcium concentration in the systemic circulation.

Symptoms of allergies and overdose

One drop of the drug Vigantol contains 670 IU of the substance, a drop of Aquadetrim contains 500 IU, and when 1000-1500 IU enters the body, side effects develop in the form of allergies. They appear:

• a red rash that spreads over the face and body (see photo for details);
• constipation or diarrhea (the intestines, as the main indicator of the functioning of the immune system, are malfunctioning);
• changes in eating behavior (baby eats poorly or refuses to eat altogether).

Indications for use

for adults

Vigantol drops are prescribed to adult patients if they have:

• osteomalacia, which developed due to a violation of mineral metabolism in people over 45 years of age, after prolonged immobilization due to injury, refusal of milk and dairy products.

for children

The drug is prescribed to children for the treatment and prevention of rickets.

In addition, Vigantol drops are prescribed for adults and children if they have the following diseases:

• osteoporosis of various etiologies;
• hypoparathyroidism and pseudohypoparathyroidism.

The drug is also prescribed for the prevention of hypovitaminosis D3 in adults and children if they are at risk and have the following pathologies:

• impaired absorption of vitamin D3;
• chronic diseases of the small intestine;
• biliary cirrhosis of the liver;
• The stomach and small intestine were removed.

Vigantol should be used with caution in pregnant and lactating patients if they have the pathologies listed above, since these categories of citizens need an adequate supply of vitamin D3.

In case of overdose, it is possible to increase the concentration of calcium in the blood and penetration of vitamin D3 metabolites through the placenta, which can provoke a delay in the physical and mental development of the fetus, as well as the development of aortic stenosis.

During lactation, you need to take into account that vitamin D3 and its metabolites pass into breast milk.

Reception of Vigantol is indicated:

• with hypovitaminosis D;
• for the purpose of preventing hypovitaminosis D and rickets;
• for the treatment of rickets;
• if calcium absorption is impaired;
• as maintenance therapy for osteoporosis;
• with hypoparathyroidism.

Taking Vigantol is contraindicated for:

• increased calcium levels in the blood and urine;
• deposition of stones in the kidneys and bladder;
• thyrotoxicosis;
• renal osteodystrophy;
• excess vitamin D in the body;
• allergic reactions to the components of the drug.

Consequences of allergies for children

The consequences of allergies are expressed in the high sensitivity of the immune system to various components of both food and pharmaceutical drugs. Skin diseases, digestive tract disorders and even frequent colds and acute respiratory viral infections are a consequence of the side effects of allergies in children. Allergies have primary and secondary symptoms.

Vitamin D allergy rashes are similar to childhood eczema

• skin rashes, redness of certain areas of the body;
• headaches;
• feeling tired and sleep disturbances.

Secondary symptoms are chronic and lead to:

• bronchial asthma, eczema;
• anaphylactic shock (difficulty breathing, decreased blood pressure, convulsions and loss of consciousness);
• Quincke's edema (an extremely severe form of allergy, expressed by swelling of the subcutaneous layers and mucous membranes).

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special instructions

With pseudohypoparathyroidism, you need to constantly monitor the development of symptoms of intoxication. Since with this pathology phases of normal sensitivity to vitamin D can be observed, it is necessary to adjust the dosage of the drug. If such a disease occurs after surgery on the thyroid gland, you need to stop using Vigantol drops as the parathyroid glands recover to prevent vitamin D hypervitaminosis.

Overdose

If recommended doses are exceeded, the following early signs of hypervitaminosis D3 may be observed:

• constipation or loose stools;
• dry mouth, thirst;
• headache;
• refusal to eat;
• metallic taste in the mouth;
• excessive fatigue;
• severe muscle weakness;
• dehydration;
• increased levels of calcium and 25-dihydrocolecalciferol in the blood;
• nausea and vomiting;
• increased concentration of calcium in urine;
• urination disorder (increased amount of urine, night and frequent urination).

Late symptoms of intoxication may include:

• pain in bones and muscles;
• increased blood pressure;
• skin itching;
• cloudiness of urine (appearance of hyaline casts, protein and leukocytes);
• redness of the conjunctiva, photosensitivity of the eyes;
• heart rhythm disturbance;
• drowsiness;
• stomach pain;
• weight loss;
• pancreatitis;
• mood swings;
• mental disorders, including the development of psychosis.

In case of a chronic overdose of vitamin D3, which can develop when taken for several weeks at a daily dosage for adults of 20 to 60 thousand IU, for children from 2 to 4 thousand IU, the following undesirable reactions may be observed:

• deposition of calcium salts in soft tissues and internal organs;
• renal and heart failure;
• growth disturbance in children.

If an overdose of the drug develops, treatment should first of all be aimed at eliminating the increased level of calcium in the blood. Depending on the patient’s well-being, the following may be prescribed:

• withdrawal of medication;
• low calcium diet therapy;
• taking glucocorticosteroids, vitamin A, C, E, group B;
• drinking large amounts of liquid;
• intravenous administration of saline, furosemide, electrolytes, calcitonin;
• prescribing hemodialysis.

There is no antidote. To eliminate the possibility of overdose, individual patients are recommended to undergo tests to determine the level of calcium in the blood.

Children and pregnant women can take Vigantol only under the supervision of a doctor.

The drug is prescribed with caution for:

1. Atherosclerotic degeneration of blood vessels and heart.
2. Severe heart and kidney failure.
3. Kidney stone disease with the formation of stones from phosphorus salts.
4. Stomach and duodenal ulcers.
5. After surgery on the parathyroid gland, dose adjustment is necessary.

First aid for a child and subsequent treatment

The first aid for children will be drug withdrawal. Next comes a change in diet. If the baby is bottle-fed, the formula is replaced with one that does not contain vitamin D. If allergies are severe, your doctor may prescribe antihistamines:

• Fenistil in drops and Cetirizine are approved for use from one month of age;
• Claritin and Zyrtec are used from six months (see also: Claritin drops: instructions for use for children).

To alleviate skin itching, use ointments Gistan, Desitin, Bepanten. Enterosgel and Polyphepam will help improve intestinal function.

Applications and dosages

for adults

To treat osteomalacia, the drug should be taken 2-8 drops per day for 12 months.

To prevent diseases caused by a lack of vitamin D3, Vigantol is prescribed in a daily dosage of 1-2 drops.

To prevent vitamin D3 deficiency, the drug for malabsorption syndrome is prescribed from 5 to 8 drops per day.

For osteoporosis, the medication is prescribed 2-5 drops per day.

For hypoparathyroidism and pseudohypoparathyroidism, the daily dosage of Vigantol, depending on the level of calcium in the blood, can vary from 15 to 30 drops. Blood calcium levels should first be checked for 4-6 weeks, then every 3-6 months, and the treatment regimen should be adjusted depending on the test results.

for children

Children should be given drops with milk or some other liquid.

For full-term healthy newborns, the drug is prescribed for the prevention of rickets, after 2 weeks of life, a drop every day.

To prevent premature babies, it should also be given 2 drops from the 2nd week of life. The medicine should be taken throughout the 1st and 2nd year of life, especially in winter.

For the treatment of rickets, the drug is prescribed from 2 to 8 drops per day, the duration of therapy should be 1 year.

For other pathologies, Vigantol drops are prescribed in the same dosages as for adults.

Preventive actions

1. strictly follow the dosage prescribed by your pediatrician and do not increase it yourself;
2. when artificially feeding, know how much vitamin the baby will receive by studying the information about the composition on the jar of baby food;
3. it is preferable to use an aqueous solution of vitamin D - it is less toxic than an oil solution;
4. In order to avoid allergic reactions, it is advisable to take a urine test from the child according to Sulkovich before purchasing the drug (the presence of rickets or an overdose is determined).

Daily walks and proper nutrition for a nursing mother and baby are a good natural source of vitamin D without side effects such as allergies. We wish you good health!

Girls, we are allergic to Aquadetrim and Vigantol, after these drugs Masuska’s cheeks are simply bright scarlet. At first we gave Aquadetrim, but I immediately noticed that my cheeks turned red, they stopped giving and everything returned to normal, then the pediatrician said that you can give Vigantol, which is also vitamin D only in an oil solution, and after it our cheeks and forehead were covered again, and that characteristically she gave it according to the instructions and after 10 days of taking it, everything appeared on our cheeks again and even more strongly than the last time. We are completely on breastfeeding, I don’t have to sin on the foods I eat, because... After the first rash I went on a very strict diet. Did anyone have a thread like this? and how did you take vitamin D, maybe mothers can take it and it will be in small quantities with milk.

We were allergic to Aquadetrim and Vigantol. Doc said, well, what can you do, anything can happen. As a result, they recommended doing 3 courses of massage per year, baths with herbs/Moor sea salt/pine extract, walking outside more often, going to the dacha in the summer, and in extreme cases, ultraviolet radiation (but we never did it). We bathed in the grass, summer at the dacha in the sun and everything was ok.

Biovitalgel, multitabs - all with additives/dyes, I gave multitas once, but didn’t even try bioital. You are tortured to expel the allergen.

Regarding breastfeeding and the passage of vitamin D into breast milk. I also thought that it was transmitted - but this is not so, only calcium is transmitted, but vitamin D is not.

Now the sun is already appearing outside - go out with your child for a walk, expose the child to the sun (without fanaticism), 10 minutes. instead of drops and no allergies.

Now we are already 1.3 m, several times a week I give 1 drop of Aquadetrim, but I watch closely all the time. So far it looks like TTT. The allergy seems to have escalated.

Yes, indeed, 5 drops is already an adult dose! We drank half a drop every 2-3 days - and still had an allergy

Vigantol is the number one drug for the prevention of rickets in newborns. Its administration helps to cope with the lack of vitamin D3 in the children's body. The medicine is easily accepted by the baby, but sometimes an allergy to vitamin D is diagnosed. What to do in case of atypical manifestations, what measures to eliminate the symptoms and how to protect the child from relapse - this is in the article.

Prevention measures

The medication is taken as prescribed by a doctor, so unauthorized withdrawal of the drug will lead to unpleasant consequences. If an allergy to Vigantol in a child worsens the quality of life, it is recommended to listen to preventive measures:

1. do not prescribe the medicine yourself, in case of a medical recommendation, do not change the dosage; the exception is cases of obvious intolerance, in which discontinuation of the drug reduces the symptoms;
2. before starting to take Vigantol, offer the child 1/2 of the prescribed single dose to establish a reaction to the drug: it is easier to prevent an allergy than to eradicate it; It is not recommended to reduce the dose of the drug if sensitivity is suspected - it is better to discontinue it until the reasons are clarified;
3. when selecting a prescription that includes vitamin D3, preference should be given to a medicine with a minimal set of auxiliary inclusions;
4. Mother's milk is a source of calcium and vitamin D, necessary for its absorption; an established breastfeeding regimen provides the baby with a sufficient amount of vitamin and eliminates rickets; in the absence of breast milk, vitamin-enriched formulas are recommended, but it is important to follow the dosage so as not to get an allergic reaction to an excess of vitamin;
5. doctors notice that allergies to Vigantol in infants are more common during teething, since resistance functions are reduced during this period;
6. ultraviolet radiation in the sun is a natural provocateur for the synthesis of vitamin D; staying in the fresh air for at least 3 hours a day provides a constant supply of the beneficial component; At the same time, it is important to understand that sunbathing in a newborn is not permissible from 11 a.m. to 4 p.m.;
7. inclusion of foods rich in vitamin D in the diet of preschoolers and adolescents will avoid the use of synthetic medicinal analogues; meat, liver, fish, eggs, dairy products are tasty and healthy components of the daily diet that help avoid rickets.

An allergy to Vigantol causes concern among parents, but discontinuation of the drug can harm the child’s growing body. Accurate diagnosis of pathology, therapeutic measures and medications reduce allergic manifestations and prevent complications from developing, and exposure to the sun helps to cope with vitamin D deficiency.