Specific and individual allergens Ige and Igg

Allergens Ige

At first glance, elements that are safe and familiar to humans can lead to allergies. Plant pollen, home care products, beauty care products, and even food products. All this can cause indignation of the immune system.

The most severe reaction is provoked by food and animal hair. To determine the allergen, special tests are performed. If you have a food allergy, the patient’s blood will have an increased level of allergens. Often the patient is not able to distinguish a true allergy from intolerance to certain foods.

Traditional food allergy Ige is an acute reaction that occurs in 2–3% of the population. It is characterized by dangerous manifestations in the form of suffocation and anaphylaxis. Signs develop quite rapidly, within 5–15 minutes from the moment the aggressive substance enters the body. This type of allergy can be caused by any food that is rightfully considered openly allergenic. For example:

• chocolate;
• peanut;
• eggs and so on.

Characteristic signs and symptoms

In most patients, negative symptoms develop a few minutes after the penetration of volatile allergens. Attention to the time of occurrence of negative symptoms and the nature of the manifestations allows us to fairly accurately predict which substance is interfering with normal life activities.

Main symptoms:

• sneezing, difficulty breathing through the nose, burning, itching in the nasal passages;
• allergic cough, shortness of breath, breathing problems, difficulty exhaling;
• pronounced swelling of the lips, neck, eyelids, cheeks;
• redness of the sclera of the eyes, burning in the conjunctiva, tearing of the eyes, swelling and hyperemia of the eyelids;
• rashes and redness on the skin, swelling of tissues;
• general weakness, low blood pressure, irritability.

Allergens Igg

Indicate a delayed allergic reaction, that is, food intolerance. The problem occurs in a larger number of people (about 20%). Appears several hours, sometimes days after consuming a certain substance. This makes diagnosis very difficult, since it is difficult to determine what exactly caused the body’s negative response.

A pathological condition occurs in response to the foods that a person most often consumes. Therefore, many do not even realize that they are the culprit of the problem. In addition, this disease is not as easy to cure as a true allergy. Diagnosis is also difficult due to the similarity of symptoms to other diseases. The danger lies in the ability of this type of allergy to cause serious diseases of internal organs.

Milenia-Biotec, Germany

Panel No. 1 Mixed allergens (20 allergens) Derm mite.
Pteronyssinus, Derm mite. Farinae, alder, birch, hazel, mixture of herbs, rye (pollen), wormwood, plantain, cat, horse, dog, alternaria alternata, egg white, milk, peanuts, hazelnuts, carrots, wheat flour, soybeans. Panel No. 2 Respiratory allergens (20 allergens) Derm mite. Pteronyssinus, Derm mite. Farinae, alder, birch, hazel, oak, mixture of herbs, rye (pollen), wormwood, plantain, cat, horse, dog, guinea pig, golden hamster, rabbit, penicillum notatum, cladosporium herbarum, aspergillus fumigatos, alternaria alternata.

Panel No. 3 Food allergens (20 allergens) Tree nuts, peanuts, walnuts, almonds, milk, egg white, egg yolk, casein, potatoes, celery, carrots, tomatoes, cod, crabs, oranges, apples, wheat flour, rye flour flour, sesame seed, soybeans.

Panel No. 4 Pediatric panel (20 allergens) House dust (Derm. Pteronyssinus mite), house dust (Derm. Farinae mite), birch, mixture of herbs, cat, dog, Alternaria Alternata (fungus), milk, alpha-lactalbumin, beta lactoglobulin, casein, egg white, egg yolk, bovine serum albumin, soybeans, carrots, potatoes, wheat flour, hazelnuts, peanuts.

Specific IgE allergens

A person who suspects he has allergic reactions should first of all get tested for immunoglobulins. This will become the basis for further diagnostics and research. It should be taken into account that the concentration of the substance changes with age. In infants up to 1 year it is 0–15 kU/l. In adults, the figure increases to 100 units.

We should not forget that increased levels of these elements lead to serious health problems. Sometimes patients receiving treatment for bronchitis, asthma, dermatitis and so on do not get the desired result. The point here is not the ineffectiveness of therapy, but the cause of the problem. Until it is eliminated, treatment will not give the desired effect.

Respiratory allergen panel: what is it?

General information:

• during an enzyme immunoassay, doctors draw venous blood and determine the amount of immunoglobulin E;
• After processing, antigen molecules are distributed into fractions. Doctors apply the material to special strips treated with substances that most often provoke respiratory allergies;
• the next step is to compare the IgE level with a special table, which contains indicators for each level of allergic reaction. Based on the results of the study, it is easy to determine the irritant that negatively affects the body of a particular person;
• the study takes, on average, 4 days, but in severe cases of an allergic reaction, express analysis is possible: the result is ready in 2 days.

Individual allergens Igg

The solution to any problem must be comprehensive. This truth is also relevant for research when making a diagnosis. Therefore, even if the patient has a normal level of IgE immunoglobulin, an Igg test must be done. In this case, be sure to take into account:

• seasonality of the problem;
• type of allergen;
• region of residence;
• patient's age.

In addition, it is important to remember that manifestations of an allergy to the smell of food often occur in the form of a cough. Any chronic disease can be caused by an increased level of IgG allergen.

OPTIGEN, Russian panel

Universal, 20 allergens Birch, ragweed (mixture), timothy, wormwood, latex, soybeans, rice, cod, wheat, peanuts, egg white, milk, aspergillus mushroom, cladosporium mushroom, alternaria mushroom, dog (epid.), cat ( epid.), cockroach (mixture), pteronysinus mite, farina mite.

Atopic, 20 allergens Pteronyssinus mite, farina mite, aspergillus, cladosporium, horse (epid.), dog (epid.), cat (epid.), timothy, wormwood, white birch, hazel (pollen), egg white, milk, cod , wheat, soy, peanuts, apple, carrots, latex.

Russian panel I, 36 allergens Dandelion, wormwood, quinoa, hazel (pollen), white birch, black alder, aspergillus, cladosporium, cockroach mix mix I, house dust, timothy, meadow fescue, hedgehog, rye (pollen), chicken, corn (food), apple, strawberry, wheat (food), potatoes, carrots, cod, beef, pork, tomato, whole egg, milk, hazelnut (food), soybeans, peas, chicken feather, dog (epid. .), horse (epid.), cat (epid.), farina tick, pteronyssinus tick.

What is the difference between IgG and IgE allergens

The main difference between the elements is in the clinical picture of the disease. The interval between consumption of an allergen and the onset of symptoms. With food intolerance, an increased level of IgG allergen is detected. Signs of an allergy appear after a certain period of time, ranging from several hours to 2-3 days.

The symptoms are not acute and do not pose a danger to human life. Often expressed in disruption of the functioning of the digestive organs, stool disorders, and rash. High content of the element leads to reactions of types 2, 3 and 4. Unlike allergen IgE, skin tests give negative results. Allergies appear both as a result of consuming large quantities of a single product, and when mixing different substances.

The IgE element provokes immediate, life-threatening reactions. Depending on the amount of allergen, they may appear on the skin, for example, hives. So in the respiratory organs:

• swelling of the mucous membranes of the larynx and mouth;
• dyspnea;
• asthma attacks;
• Quincke's edema;
• anaphylactic shock.

Skin tests give positive results. Signs of the disease appear after consuming even a minimal amount of a dangerous product.

Respiratory allergies: causes of development

Acute and moderate symptoms develop after inhalation of microparticles of substances that irritate the receptors of the mucous membranes. Antigens penetrate the respiratory tract and provoke a response from the immune system. The interaction of immunoglobulin E and the allergen releases a large volume of inflammatory mediators, symptoms appear on the mucous membranes, skin of the face and body, and in the eye area.

After contact with irritants, the body intensively produces immunoglobulins E and G. In most cases, an acute immediate reaction develops, and the IgE level increases noticeably. It is this factor that doctors use during immunoblotting testing.

The release of inflammatory mediators against the background of increased levels of immunoglobulin E provokes the main clinical signs of respiratory allergies from the respiratory system. With prolonged exposure to an irritating substance, another type of reaction develops - a delayed type. Allergic cough, sneezing, swelling, lacrimation appear, but rather weakly; the main symptoms are itching and skin rashes (urticaria).

Main types of volatile allergens:

• mold spores;
• pet fur and skin particles;
• pollen of certain plants;
• dust: house and book dust.

Respiratory allergies appear throughout the year or during a certain season. Based on the nature of the negative symptoms and the time of appearance of the main signs of the disease, it is easier to establish that the patient suffers from hay fever, allergic rhinitis, conjunctivitis or bronchitis. The seasonal and year-round form of the disease when inhaling volatile allergens causes noticeable discomfort to a person. Lack of therapy provokes the transition of the disease to a severe form; in advanced cases, bronchial asthma often develops.

Check out our selection of effective folk remedies for runny nose and nasal congestion due to allergies.
Instructions for using calcium gluconate in ampoules for allergies are described on this page.

Decoding the results

The RAST scale was developed to interpret the data. With a low level of sensitization of the body and no tendency to allergic reactions, immunoglobulin E levels do not exceed 0.35 kU/l. Deviation from the norm has certain values ​​for each level of allergization of the body.

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