Cetrine for breastfeeding and lactation. Instructions for use, reviews

Can it be used for breastfeeding?

Claritin is a second-generation drug based on loratadine. The instructions for use indicate that use during lactation is contraindicated.

However, according to official data from the British Society of Immunology and Allergology and the American Academy of Pediatricians, Claritin is compatible with breastfeeding; no side effects were observed in mothers or children based on research results.

Allergists prescribe it to nursing women when necessary. It is important to take the drug strictly in accordance with the doctor’s recommendations, then the treatment will be effective and the risk to the child will be minimal.

Should I stop breastfeeding during allergy treatment?

Antihistamines are prescribed by your doctor if an allergy-related health problem is detected. As is known, there are cases of particularly severe course of this pathological process, which requires immediate treatment, and often hospitalization. The situation can become significantly more complicated if the patient is pregnant or breastfeeding a baby. As a rule, pediatricians do not recommend completely eliminating breastfeeding, since mother's milk is important for the proper and healthy development of the child. But you can take a short break during therapy during this period to maintain lactation by expressing milk.

A nursing mother is recommended to exclude from her diet all foods that can provoke allergies in both her and the baby: radishes, tomatoes, red apples, legumes, onions, garlic. If for some reason it is necessary to take decoctions of medicinal herbs, it is important to first make sure that they will not have a negative reaction on the body. In some rare cases, there is intolerance to chamomile flowers, despite the fact that its infusions and decoctions can eliminate skin irritations and reduce inflammation.

Indications for use

Claritin is recommended for use in the following cases:

dermatitis of allergic origin;
seasonal or year-round rhinitis;
conjunctivitis of allergic origin;
pseudo-allergy to food - coffee, chocolate, strawberries, oranges, etc.;
chronic urticaria.

Important! If any allergic symptoms appear, first of all you need to exclude the source that provoked them, otherwise taking the medicine will be pointless.

Instructions for use, dosage

Cetrin is used during breastfeeding when the benefits of the drug for the health of the mother are significantly higher than the potential risks for the baby. The specific dose is determined by the doctor.

The standard amount of the substance prescribed to adults per day is 10 mg. This amount of the drug is taken once a day with a glass of clean water. However, in order to ensure maximum safety for the child, nursing mothers are often prescribed a children's dose of 5 mg. In severe forms of allergies, you can take the same amount of the substance after 12 hours.

The tablets can be used regardless of food intake or time of day. They are taken orally without chewing. It is better not to use the product on an ongoing basis to avoid the accumulation of a large amount of cetirizine in the body.

Contraindications and side effects

According to the instructions for use, there are few contraindications for taking Claritin:

hypersensitivity to components or individual intolerance;
children under two years of age;
pregnancy and lactation.

Adverse reactions most often occur when the recommended dosage is not followed and contraindications are violated. Possible manifestations include:

lethargy, headache, feeling tired;
dry mucous membranes;
nausea, inflammation of the gastric mucosa;
the frequency of myocardial contractions increases;
liver dysfunction.

You cannot increase the amount of medication you take on your own. If this happens, you should immediately consult a doctor to relieve symptoms of overdose and improve the condition of the body.

Features of allergies in nursing mothers

It is impossible to predict what form of allergy may occur after childbirth, even if the allergy appeared earlier. Pregnancy and the birth process are a lot of stress for the body, so after them, allergies may occur in a more acute form or appear for the first time.

Doctors note that women who suffered from high blood pressure and edema during pregnancy are much more likely to have allergic reactions after childbirth than those who did not have such problems.

Allergies in nursing mothers have some features:

increased allergic reactions that appear before pregnancy;
a wide range of possible allergens;
the likelihood of similar reactions developing in a newborn baby;
increased susceptibility of the child to allergens dangerous to the mother and acute respiratory infections.

The course of allergies usually occurs in one direction. The disease may be characterized by respiratory symptoms (runny nose, dry cough, itchy nose) or gastrointestinal symptoms (indigestion, intestinal spasms). The most common are skin manifestations: redness, rash, blisters on the skin.

If signs of an allergy appear, a nursing mother should seek help from a doctor. You should not expect the allergy to go away on its own; this can lead to worsening of the disease and complications.

Recommendations

Claritin is prohibited from being taken during lactation according to the official instructions for the drug due to its high absorption. It passes into breast milk in fairly large quantities, reaching its maximum two hours after administration. Therefore, it is prescribed only by the attending physician, under whose supervision the course of treatment takes place.

In order not to harm the baby, it is necessary to take the medicine immediately after feeding. After this, do not put the baby to the breast for three hours. Then continue feeding as usual.

Allergists usually prescribe Claritin in combination with calcium gluconate. It helps enhance the effect of the main drug and is approved for use during lactation.

In what form should I take it?

This antiallergic drug is available in two forms: syrup and tablets. Syrup is most often recommended for children from 2 to 12 years old; adults are most often prescribed one tablet per day.

The course of treatment is prescribed individually, depending on the manifestations of allergies and the general condition of the patient. Typically, the period of taking the medicine is from 3 to 10 days. In case of liver or kidney failure, the drug is taken every other day.

Should I stop lactation?

If a mother develops allergic reactions, it is not recommended to stop breastfeeding. Even if the baby is predisposed to allergies, breast milk will protect against exposure to allergens and help fight them. The use of medications, if the recommendations are strictly followed, will also not affect the baby.

If, during the course of treatment, the mother or child exhibits any side effects or their health worsens, it is necessary to stop taking the medicine and consult a doctor.

Tavegil

Tavegil belongs to the pharmacological group of antihistamines. The main active ingredient is clemastine.

The drug has antihistamine and antiallergic effects. It also has an antipruritic effect. The therapeutic effect is achieved due to the ability of certain components of the drug to block the so-called H1 histamine receptors and reduce capillary permeability.

Tavegil is used in the case of hay fever, urticaria, allergic rhinitis, eczema, dermatosis, dermatitis. Injection of the drug will eliminate allergic or anaphylactic shock.

Release form and composition

Dosage forms of Tavegil:

Tablets: flat, round, with a beveled edge, white or almost white, with “OT” engraved on one side and a score line on the other (5 pcs. in blisters, in a cardboard pack of 2, 3 or 6 blisters; 10 pcs. in blisters, in a cardboard box 1, 2, 3 or 6 blisters);
Solution for intravenous and intramuscular administration: colorless or from light yellow to pale greenish-yellow, transparent (2 ml in ampoules, 5 ampoules in plastic trays, 1 tray in a cardboard box);
Syrup for oral administration (60 ml in dark glass bottles, 1 bottle in a cardboard box complete with a dispenser cap).

Composition of tablets (1 pc.):

Active ingredient: clemastine (in the form of hydrofumarate) – 1 mg;
Auxiliary components: corn starch, lactose monohydrate, magnesium stearate, povidone and talc.

Composition of the solution (in 1 ml):

Active ingredient: clemastine (in the form of hydrofumarate) – 1 mg;
Auxiliary components: ethanol, sorbitol, sodium citrate dihydrate, propylene glycol, water for injection.

Syrup composition (5 ml):

Active ingredient: clemastine (in the form of hydrofumarate) – 0.5 mg;
Auxiliary components: methyl p-hydroxybenzoate, propyl p-hydroxybenzoate, disodium hydrogen phosphate, sorbitol 70%, potassium dihydrogen phosphate, sodium saccharin, propylene glycol, demineralized water, mixture of fruit flavoring additives (ABRAC S-2718).

Pharmacodynamics

The active component of Tavegil, clemastine, is a blocker of H1-histamine receptors and belongs to ethanolamine derivatives. It is characterized by a strong antihistamine and antipruritic effect.

The drug begins to act quickly, the duration of action reaches 12 hours. Clemastine prevents the development of vasodilation and smooth muscle contraction that histamine induces.

Tavegil exhibits antiallergic and anticholinergic effects, reduces itching, slows down the formation of edema, inhibits exudation, and reduces the permeability of blood vessels and capillaries.

Pharmacokinetics

After oral administration of Tavegil, clemastine is almost 100% absorbed from the gastrointestinal tract (GIT). Its maximum plasma concentration is recorded 2–4 hours after administration.

The degree of binding to blood plasma proteins reaches 95%. The drug is excreted from the body in a biphasic manner, the corresponding half-lives being 3.6±0.9 and 37±16 hours. Clemastine is actively involved in hepatic metabolism processes.

Excretion of metabolites occurs primarily through the kidneys (approximately 45–65%), and the active substance, unchanged, is found in urine only in trace concentrations.

In nursing women, clemastine may pass into breast milk in small quantities.

When is Tavegil prescribed?

Therapy with Tavegil can be prescribed if there is a history of the following diseases:

allergic and chronic rhinitis;
conjunctivitis;
various forms of dermatoses of an allergic nature;
angioedema;
food allergies.

In some cases, it can be used as an adjuvant as part of complex therapy for the following diseases:

pneumonia;
arthritis;
obstructive bronchitis;
nephritis;
bronchial asthma.

Contraindications

simultaneous use of monoamine oxidase inhibitors (MAO);
diseases of the lower respiratory tract, including bronchial asthma;
breastfeeding period;
individual intolerance to Tavegil components.

In addition, it is contraindicated to prescribe the solution for intravenous and intramuscular administration during pregnancy, with fructose intolerance and for intra-arterial administration.

Tavegil tablets should not be taken during pregnancy, or in patients with glucose-galactose malabsorption syndrome, severe lactase deficiency, or galactose intolerance.

Age contraindications for prescribing Tavegil to children:

solution: up to 1 year;
tablets: up to 6 years;
syrup: up to 1 year.

According to the instructions, Tavegil is recommended to be prescribed with caution for stenosing gastric ulcers, pyloroduodenal obstruction, prostatic hypertrophy complicated by urinary retention, obstruction of the bladder neck, hyperthyroidism, increased intraocular pressure, arterial hypertension and other diseases of the cardiovascular system.

In addition, the syrup should be used with extreme caution in cases of pyloric stenosis and angle-closure glaucoma.

Analogs

There are a lot of antiallergic drugs in pharmacies. If Claritin is intolerant, it can be replaced with an analogue that will not affect lactation.

First of all, these are second and third generation drugs:

Alerpriv, Clargotil, Clalergin - like Claritin, the active ingredient is loratadine, it can be used during breastfeeding.
Terfenadine, Acrivastine, Ebastine, Levocetirizine are low-risk drugs and should be used with great caution.
Desloratodine, Fescofenadine - compatible with breastfeeding according to the e-lactancia directory.

First-generation allergy medications have sedative properties and side effects such as drowsiness, lack of concentration, and irregular heart rhythms. If necessary, Diphenhydramine can be used from drugs in this group, but in small doses, and only if the child has reached 1 month of age.

Clemastine and Diprazine affect not only the child, but also lactation, inhibiting it; their use during breastfeeding is not recommended.

Important! Only an allergist can choose an analogue for a prescribed drug; you should not do this yourself.

Antihistamines and their effects on the baby or fetus

Usually, if necessary, modern specialists prescribe antihistamines such as cetirizine, tavegil, loratadine, suprastin. These medications can be taken while breastfeeding as there are no negative results regarding their effect on the baby's body. It should also be remembered that drugs belonging to the first generation can cause drowsiness in the baby, these include: tavegil and suprastin.

If you need to continue breastfeeding your baby, you can take loratidine or cetirizine. The drug Erius is not recommended for both pregnant and nursing mothers, since the substances included in its composition can adversely affect the health of the baby.

Diazolin: composition, indications, dosage, side effects

From the digestive system: rarely - dry mouth, dyspeptic symptoms due to irritation of the gastric mucosa. From the central nervous system and peripheral nervous system: dizziness, paresthesia, increased fatigue, tremor, drowsiness are possible. From the hematopoietic system: in isolated cases - granulocytopenia, agranulocytosis. During the treatment period, you should refrain from engaging in potentially hazardous activities that require increased attention and speed of psychomotor reactions: driving vehicles or working with machinery. Source: vidal. Release form:. Active substance:. Mebhydrolin Mebhydrolin.

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Review of dosage forms

The drug is available in tablets, drops, and syrup. The main component of the drug is cetirizine. The dosage forms differ in the excipients:

corn starch;
lactose;
povidone;
stabilizer E464;
titanium dioxide;
talc;
magnesium stearate;
macrogol;
dimethicone emulsion.

methyl, propyl ester of para-hydroxybenzoic acid;
glycerol;
propylene glycol;
sodium salt of acetic acid;
anhydrous ethanoic acid;
water.

The pills are white, oblong in shape, with a line in the middle. Liquid pharmaceutical forms have a clear or yellowish tint. The tablets are packaged in blister packs, and the syrup and drops are in dark bottles with a dropper on the neck.

Cetirizine blocks histamine receptors (H1). The product exhibits a pronounced anti-allergenic effect, prevents the development of allergies, and alleviates existing symptoms. The medication eliminates itching, eliminates vascular permeability, and prevents the release of exudate into the tissue (during inflammation).

The drug relieves early allergy symptoms, prevents the migration of immune cells from the bloodstream to the site of allergen penetration, and inhibits the release of mediators that are involved in the delayed phase of the allergic reaction. Strengthens blood vessels, prevents swelling, eliminates spasm of smooth muscles. Neutralizes the skin's reaction to histamine and specific allergens. Relieves the manifestation of cold urticaria.

If the dosage is observed, the antihistamine does not have a sedative effect. The treatment is carried out in a course, the drug does not provoke addiction. The therapeutic effect appears after 20 minutes and lasts throughout the day. Cetirizine quickly penetrates the blood through the intestinal walls and is excreted in the urine.

An antihistamine is used for the following reactions:

Runny nose, inflammation of the conjunctival membrane of an allergic nature.
An inflammatory skin lesion that occurs after contact with an allergen.
Rhinoconjunctivitis as a reaction to plant pollen.
Hives.
Quincke's edema.

If allergy symptoms occur, you should consult a doctor.

Allergies after childbirth: causes

A woman’s body is weakened after childbirth, and it takes time to restore the organs and systems of the body. The immune system is no exception. Indeed, in order to safely bear a child, and not cause its rejection (the conceived life is perceived as a “stranger” thanks to the father’s “inheritance”), mechanisms in the body of a pregnant woman are activated that suppress protective forces.

Even if the woman who gave birth has never had this disease, the allergy after childbirth may make itself felt for the first time, and in mothers prone to it, the existing allergy may worsen. It would seem, where does allergies come from when immunity is reduced? After all, an allergic reaction is an overly strong response of the immune system to harmless substances mistakenly perceived as “enemies.”

But the statistics are consistent - immunodeficiency states are often combined with type 1 allergic reactions - urticaria, eczema, anaphylactic shock, false croup, atopic bronchial asthma. Signs of decreased immune defense are chronic and frequent infections of the upper respiratory tract, skin and mucous membranes.

The reasons for this condition include depletion of the body's reserves, poor nutrition and lack of vitamins and minerals, large blood loss, iron deficiency anemia, inflammatory diseases, chronic fatigue and stress - everything that a woman often faces after childbirth.

Breastfeeding is a resource- and energy-intensive process, and in the presence of reduced immune defense after childbirth and the factors listed above, further development of immunodeficiency can occur. The state of immunity and allergies are closely related.

It is believed that increased histamine release occurs when the body is rehydrated (dehydrated) and the level of calcium in the blood is high, which can sometimes be observed during breastfeeding. In this way, moisture is retained when there is insufficient water supply, which is due to the regulatory function of histamine in the body’s water metabolism.

Diazolin during breastfeeding: is the drug allowed for young mothers?

Diazolin is a relatively safe drug that protects against various allergic reactions. However, lactating women are a difficult category of patients who require a special approach. How safe is Diazolin for nursing mothers? More on this later. Tablets are white or almost white, round, flat-cylindrical, scored and chamfered. Packed in contour cells of 10 pieces and polymer jars of 10, 20 and 25 pieces. Dragee is white, regular spherical in shape, with an even, smooth and uniformly colored surface.

In a cross section, two layers are visible. Packed in contour cells of 10 pieces. Diazolin is an antihistamine drug from the group of histamine blockers, which has antiallergic, antipruritic, m-anticholinergic and slight sedative effects.

The main component blocks histamine receptors, weakens spasm of the smooth muscles of the bronchi and intestines. Unlike other first generation antiallergenic drugs, Diazolin has a less pronounced sedative effect. In addition, the medication has a slight anticholinergic effect, blocks the influence of the parasympathetic nervous system on organs and glands and has an analgesic effect. The drug is quickly absorbed into the blood from the gastrointestinal tract.

The healing properties appear after 30 minutes and then persist for 48 hours. The medication is excreted from the body through the kidneys. Mebhydrolin has a weak, but still sedative effect. During the period of therapy you should avoid:. During treatment with the drug, it is not recommended to drive vehicles or perform other potentially dangerous activities that require maximum concentration.

Diazolin is often well tolerated, however, if it is used for a long time, the risk of the above side effects increases. Therefore, doctors in most cases do not prescribe the drug for allergic diseases with a chronic course.

The main essence of Diazolin is to relieve the main symptoms that a patient has during acute allergic reactions as quickly as possible. It is also necessary to pay attention to the fact that the drug does not belong to the first generation, so the main component slightly penetrates directly into the nervous system.

Thanks to this action, Diazolin does not cause a hypnotic effect. It is important to know the rules for using the medication to avoid the side effects described above.

The tablets are sold without a prescription; each package must contain instructions for Diazolin, which describe all the indications for the use of the drug and the dosage for different ages.

The release form for this age group is granules in a bottle. Diazolin for children is mixed in ml of warm water. Mix the contents thoroughly and stir for several minutes. The resulting suspension must be poured into a graduated glass to accurately determine the dose.

The product should be taken for a week after meals. Be sure to shake the suspension first. According to the instructions, the following rules for using the medicine for a child are outlined:. All people over 12 years of age take this medication in the same dosage.

Diazolin for adults is taken 2 times a day in a dosage of mg. At one time, the dose should not exceed mg, the maximum daily value is mg. The instructions for use, which are in the packaging of the medicine, describe in detail how to take Diazolin for adults.

The duration of the course of treatment is determined individually by the doctor. This is a relatively strong antiallergic drug, so taking medications while pregnant is highly undesirable. It is strictly prohibited to use it in the second and first trimester. Diazolin is also contraindicated during breastfeeding, because the active substance can enter the bloodstream through the intestines and pose a threat to the baby. For a child under 3 years of age, the medicine will be dangerous even in the quantities contained in breast milk.

The pharmaceutical drug must be consumed with food or immediately after taking it. Adult patients are prescribed from 50 to mg at a time at least three times a day, depending on the severity of the symptoms of the disease.

In children, starting from 3 years, 25 to 50 mg is recommended. The recommended dose of diazolin is from to mg per day. Your doctor may increase this dosage to mg.

The duration of the treatment course is selected individually in accordance with the severity of the disease and its course. Diazolin is ineffective for angioedema and anaphylactic shock, since it does not have a rapid effect, and these conditions require emergency medical intervention.

In addition, it is important to consider that tablets can enhance the activity of sedative medications that have a hypnotic and sedative effect. It is worth special mentioning the use of diazolin during pregnancy, as well as during breastfeeding. During these conditions, the patient may be prescribed antihistamines and, in particular, diazolin, if allergic symptoms pose a threat to the patient’s life.

However, the use of the drug is permitted only under the supervision of the attending physician. When prescribing diazolin during this crucial period for a woman, the attending physician must exercise maximum caution, having previously familiarized himself with the course of pregnancy. As a rule, pregnant women should take 1 tablet per day with food, unless otherwise prescribed by a doctor.

It is important to consider that these tablets have the most prolonged long-term effects among drugs in this group. This is an important factor when choosing a drug to relieve allergies during pregnancy. Any drug treatment should be selected only by a doctor, therefore independent withdrawal or replacement of diazolin is strictly prohibited!

This can lead to serious health complications. Sometimes, if a drug is used incorrectly to relieve allergy symptoms, an overdose is observed, manifested by the following symptoms: First aid for a drug overdose consists of urgent gastric lavage to remove toxic substances from the body. Further treatment of allergies is carried out in accordance with the symptoms. How to take for adults? Children from the age of twelve, as well as adults, use the drug once or twice a day at a dose of mg.

The maximum single dose for adults should be mg; adults can take mg of Diazolin per day. Children five to twelve years old can take 50 mg two to three times daily.

Children's Diazolin is used as follows: ml of warm boiled water is added to the bottle containing the granules. The contents must be mixed very thoroughly, for which you need to stir for several minutes. After this, the suspension is given to children in doses that can be easily determined using the supplied graduated glass. Overdose increases the likelihood of side effects.

In this situation, the drug is discontinued and symptomatic therapy is carried out, as well as gastric lavage. If you take this antihistamine incorrectly, then the main side effects may intensify.

In this case, it is necessary to carry out gastric lavage as soon as possible. Also, if necessary, the patient should undergo symptomatic treatment. Diazolin and its analogues should be taken orally with meals. There is no need to chew the drug; it is recommended to drink it with plenty of water. The price of Diazolin is 90 rubles. You can buy it in a regular pharmacy or in an online store; it is not a rare drug. A single dosage of tablets and yeast for adults is mg once a day.

An increase to mg per day is allowed. Diazolin is taken during or immediately after a meal, washed down with a sufficient amount of clean still water. The average duration of the treatment course is 5 days.

It can be up to days, taking into account the existing symptoms and the nature of the disease. The drug is prone to addiction, so it is not used for more than 10 days in a row. If allergy symptoms do not go away, then you should consult a doctor to replace it with another similar antihistamine.

If side effects appear from taking Diazolin, then most likely the cause is an overdose. In this situation it is worth: Symptoms of a drug overdose: loss of coordination of movements, drowsiness, confusion. In the future, as Diazolin is absorbed, signs of depression of the functions of the central nervous system may increase, and there is a risk of coma.

An overdose of the drug can also lead to a stimulating effect on the central nervous system, which is more often observed in children: increased excitability, sleep disturbance, tremor, and irritability. Manifestations of anticholinergic action may also appear: dilated pupils, gastrointestinal disorders, epigastric pain, nausea, vomiting, flushing of the upper body.

According to the instructions, Diazolin should not be taken while breastfeeding. This is explained by the fact that the drug enters the newborn’s body with milk and can harm him. The baby’s body is sensitive to medications, and certain components of Diazolin can cause allergies. But, despite the risk, an antihistamine is prescribed to lactating women. The doctor prescribes the drug to a lactating woman if the benefit to the mother and newborn is higher than the potential risk.

Sometimes doctors advise transferring the baby to artificial feeding at the time of treatment. You can continue breastfeeding after you stop taking Diazolin. Thus, Diazolin is allowed to be taken by lactating women only when absolutely necessary and as prescribed by a doctor.

Indications and effect of the drug

Zodak can be used to treat acute and chronic allergic conditions. It is prescribed for rhinitis (seasonal and year-round) to eliminate:

itching and sneezing;
swelling of the mucous membrane of the respiratory tract and facial skin;
lacrimation, inflammation and redness of the conjunctiva caused by contact with the allergen;
allergic dermatosis with rashes and blisters that are constantly renewed.

The active ingredient of the medicine is cetirizine. This substance is a histamine receptor antagonist. It prevents the binding of histamine to the receptor, disrupts their interaction, thereby inhibiting the work of the biogenic amine. Cetirizine prevents the physiological effect of high histamine levels in the body.

Once in the blood, Zodak reduces the sensitivity of the immune system to allergen exposure. The medicine effectively inhibits the development of allergic reactions, which can greatly alleviate the patient’s condition. The medication reduces the sensation of itching and prevents the release of fluid into the intercellular space at the site of inflammation.

Zodak prevents the formation of blisters in the early stages of an allergic response. The drug prevents the appearance of edema. It does not allow skin thickening and redness to develop in the later stages of an allergic reaction. The active substance Zodak prevents the release of inflammatory mediators, the presence of which leads to a local increase in temperature.

The drug reduces the speed of movement of leukocyte cells through the bloodstream into the area of inflammation:

eosinophils;
segmented basophils;
neutrophils.

Slowing down the migration of leukocytes leads to a decrease in skin manifestations in the form of rashes and swelling. The drug relaxes smooth muscles, relieves bronchospasm, and reduces the permeability of small blood vessels. Zodak reduces the manifestation of cold urticaria.