CLARITIN or SUPRASTIN: which is better and what is the difference, differences in compositions, reviews from doctors: what to do and how to treat, reasons, what to take

Good afternoon, many will be interested in understanding their health and their loved ones, and I will tell you my experience, and we will talk about the best antihistamines of the 4th generation. Most likely, some details may differ, as was the case with you. Please note that you should always consult with highly specialized specialists and not self-medicate. Naturally, you can quickly find the answer to the simplest questions and diagnose yourself. Write your questions/suggestions in the comments, and together we will improve and supplement the quality of the material provided.

Medicine "Cetirizine"

This is a fairly effective remedy. Like all modern 4th generation antihistamines, the medicine is practically not metabolized in the body.

The drug has proven itself to be highly effective for skin rashes, as it is able to penetrate perfectly into the epidermis. Long-term use of this medication in children suffering from early atopic syndrome significantly reduces the risk of progression of such conditions in the future.

2 hours after taking the tablet, the desired lasting effect occurs. Since it lasts for a long time, taking 1 pill per day is enough. Some patients can take 1 tablet every other day or twice a week to achieve the desired result.

The medicine has a minimal sedative effect. However, patients suffering from kidney pathologies should use this remedy with extreme caution.

The drug in the form of a suspension or syrup is approved for use in children from two years of age.

3rd generation drugs

These are active metabolites. They have excellent antiallergic properties and have a minimal list of contraindications. If we talk about effective antiallergic drugs, then these drugs are precisely modern antihistamines.

Which drugs from this group are the most popular? These are the following medications:

"Zyrtec";
"Cetrin";
Telfast.

They do not have a cardiotoxic effect. They are often prescribed for acute allergic reactions and asthma. They provide excellent results in the fight against many dermatological diseases.

Impact on the body

To understand how 4th generation antihistamines differ, you need to understand the mechanism of action of antiallergic drugs.

These medications block H1 and H2 histamine receptors. This helps reduce the body's reaction to the mediator histamine. Thus, the allergic reaction is relieved. In addition, these drugs serve as an excellent prevention of bronchospasms.

Let's consider antihistamines of all generations. This will allow you to understand the advantages of modern means.

The drug "Levocetirizine"

This remedy is better known as “Suprastinex”, “Cesera”. This is an excellent drug that is prescribed to patients suffering from an allergic reaction to pollen. The remedy is prescribed in case of seasonal manifestations or year-round. The drug is in demand in the treatment of conjunctivitis and allergic rhinitis.

It is recommended to take the medicine in the morning or during meals. The drug should not be combined with alcohol.

The drug has proven itself to be highly effective for skin rashes, as it is able to penetrate perfectly into the epidermis. Long-term use of this medication in children suffering from early atopic syndrome significantly reduces the risk of progression of such conditions in the future.

Claritin for children (syrup) - instructions for use

various allergic reactions;
allergic skin rashes, including urticaria;
year-round and seasonal rhinitis of allergic origin.

"Claritin" is also prescribed for such symptoms of allergic rhinitis as frequent sneezing, swelling of the nasal mucosa, itching in the nose, as well as itching and increased tearing of the eyes.

The most popular analogues of Claritin

All of the above drugs have an antihistamine effect and their indications for use are the same as Claritin. But practice shows that most often, when choosing an antihistamine, allergy patients are faced with a choice between Claritin and analogue drugs such as:

"Erius";
"Cetrin";
"Zodak".

Next, we will briefly look at the composition, indications for use and average cost of each of these drugs. We will also try to compare these drugs and find out their disadvantages and advantages in comparison with Claritin.

Claritin and Zodak: how are they different and which is better?

Allergies are a fairly common ailment that affects even children.
Therefore, pharmacies always have a huge selection of antihistamines. Popular allergy medications include Claritin and Zodak. Users often ask the question: which of these drugs is better and more effective? This article will help you figure it out.

Claritin

Claritin is a representative of the third generation of drugs that reduce the amount of histamine. Pharmacological companies produce medicine in two forms: tablets and syrup. It is noted that allergy symptoms significantly weaken within a quarter of an hour after consumption. The action can last up to a day.

The main advantage of Claritin is that it does not become addictive . Unlike other antiallergic drugs, it does not affect the nervous system, does not cause drowsiness or inhibition of psychological reactions. Therefore, the medicine is a good option for drivers and anyone whose profession requires increased attention.

In what cases is Claritin prescribed?

Claritin is prescribed for various types of allergies, expressed in:

Allergic runny nose, coughing and sneezing.
Edema of allergic origin.
Hives and other skin reactions.
Allergy to bites of mosquitoes, midges and other insects.
Pollinosis.

Claritin is also used in cases of false allergies caused by consuming large amounts of hypoallergenic foods. Due to the drug's ability to relieve bronchospasm, it is used to treat bronchial asthma.

Claritin quickly removes unpleasant manifestations of allergies. This is a real salvation if the patient’s eyes hurt, tears flow, or his nose is stuffy.

The drug in tablet form can be taken by children from the age of three, and the syrup is given to children from the age of two.

In what cases is it contraindicated?

Claritin has a number of contraindications that must be taken into account. So, it is strictly forbidden to use it:

Infants.
Pregnant and lactating women.
Persons with liver problems.
For lactose, fructose, and sucrose intolerance.

Side effects

Medical practice shows that Claritin is quite well tolerated. In rare cases, side effects may occur such as:

Drowsiness
Headache.
The appearance of a rash on the skin.
Cardiopalmus.
Nausea.

Zodak

This drug is a representative of the second generation of anti-allergy products. The medicine can be found in pharmacies in three forms: drops, tablets and syrup.

The main principle of action is the same as that of Claritin - blocking H1 histamine receptors. Zodak relieves inflammation, swelling of the mucous membrane, and itching well. Almost immediately after taking this medicine in any form, the allergic reaction becomes much less pronounced.

When is the Zodak appointed?

The drug "Zodak" is prescribed for such manifestations of allergies as:

Hay fever.
Allergic rhinitis (both seasonal and year-round)
Hives.
Quincke's edema.
Allergy manifested in the form of dermatosis.

As for children, Zodak drops can be given after reaching the age of one, and syrup from two years. Taking the drug in tablets is allowed only from the age of six.

Contraindications

There are some situations in which taking the drug seems impossible:

The period of gestation and breastfeeding.
Acute renal failure.
Child's age.

Which is better to choose from these drugs?

The drugs Claritin and Zodak do not have significant differences . But some nuances allow you to make a choice in favor of one medicine or another. Obviously, a child over one year old can only be given Zodak drops. Many doctors are inclined to believe that Zodak is better absorbed by the child’s body.

Zodak has a greater effect on the nervous system, so it is preferable for drivers and other people whose profession requires concentration and increased attention to take Claritin.

Since taking Zodak can cause undesirable reactions from the cardiovascular system, it is not prescribed to patients with heart problems.

The fact that long-term use of Claritin is not addictive makes it possible to use it as a prophylactic agent and during long-term therapy. Therefore, it is well suited for people whose allergies have become chronic.

Many people prefer Claritin because this drug has
a longer effect .
Often it is enough to take a pill once to forget about unpleasant allergy symptoms for a day. Claritin begins to work very quickly . This characteristic makes it indispensable for the rapid development of an allergic reaction. For example, Quincke's edema or the consequences of insect bites are well relieved.

The main advantage of Zodiac is that its cost is much lower compared to Claritin. However, it is significantly inferior to the latter in effectiveness and, moreover, causes a strong desire to sleep. Claritin lasts much longer but has fewer side effects.

Zodak drops do not contain sugar, so people suffering from diabetes should give it preference.

When choosing a drug, the opinion of the attending physician should play a decisive role. Neither Claritin nor Zodak should be prescribed to yourself , much less given to small children.

You should also take into account the presence of concomitant diseases for which you cannot take any of these drugs.

Each person's body has its own individual characteristics. For some, for example, Zodak helps better than Claritin. Therefore, when choosing a drug, you should, first of all, rely on the recommendations of your doctor, subjective feelings and the presence of contraindications.

Source: https://vchemraznica.ru/klaritin-i-zodak-chem-oni-otlichayutsya-i-chto-luchshe/

Zodak is another antihistamine

Just like all the Claritin analogues we are considering, Zodak is a long-acting drug. The main active ingredient of Zodak (as well as Cetrin) is cetirizine. The drug is available in the form of tablets and drops. Indications for the use of this drug are:

Quincke's edema;
allergic dermatoses;
conjunctivitis and rhinitis of allergic origin;
hay fever
hives.

1 Zodak tablet contains 10 mg of cetirizine, the same amount of active ingredient is contained in 1 ml of drops. This dosage is enough for the antihistamine effect of Zodak to last 24 hours after taking it. On average, the cost of a bottle of drops (20 ml) is 200 rubles, and the price for a package of tablets (10 pcs.) varies around 140 rubles.

Like the previous analogue "Cetrin", "Zodak" belongs to the second generation of antihistamines, and in terms of the strength of its therapeutic effect and the number of side effects it is inferior to "Claritin".

We recommend reading: Propolis for cough: adults and children, use of tincture for gargling.

But for the sake of fairness, it is worth noting that most pediatricians, when making prescriptions for their young patients suffering from allergies, do not prefer Claritin, but Zodak drops.

In cases with adult patients, therapists and allergists recommend starting to take antihistamines immediately with Claritin, since its effect is much stronger and more effective than that of Zodak.

Indications for use of Claritin

The effectiveness of Zyrtec is quite similar to Claritin - this means that the ability of the drug substance to provide the maximum possible effect is similar.

For example, if the therapeutic effect of Zyrtec is more pronounced, then using Claritin even in large doses will not achieve this effect.

Also, the speed of therapy - an indicator of the speed of therapeutic action - is approximately the same for Zyrtec and Claritin. And bioavailability, that is, the amount of a drug reaching its site of action in the body, is similar. The higher the bioavailability, the less it will be lost during absorption and use by the body.

The safety of a drug includes many factors.

At the same time, with Zyrtec it is quite similar to Claritin. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others.

The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Zyrtec does not have any risks when used, just like Claritin.

Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Zyrtec and Claritin.

Based on the instructions. The number of contraindications for Zyrtec is quite similar to Claritin and is small. This is a list of symptoms with syndromes, diseases, various external and internal conditions under which the use of Zyrtec and Claritin may be undesirable or unacceptable.

Like safety, addiction also involves many factors that must be considered when evaluating a drug.

So, the totality of the values of such parameters as “o syndrome” in Zyrtec is quite similar to the similar values in Claritin. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body.

And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, Zyrtec has a fairly low incidence of “syndrome”, just like Claritin.

Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.

Zyrtec's side effects are almost the same as Claritin's. They both have few side effects. This implies that the frequency of their occurrence is low, that is, the indicator of how many cases of an undesirable effect of treatment are possible and registered is low. The undesirable effect on the body, the strength of influence and the toxic effect of Zyrtec are similar to Claritin: how quickly the body recovers after taking it and whether it recovers at all.

This includes dose selection taking into account various conditions and frequency of doses. At the same time, it is important not to forget about the release form of the drug; it is also important to take it into account when making an assessment.

The ease of use of Zyrtec is approximately the same as Claritin. However, they are not convenient enough to use.

The drug ratings were compiled by experienced pharmacists who studied international research. The report is generated automatically.

Last update date: 2019-09-19 05:59:50

The drug Claritin has antiallergic, antihistamine and antipruritic effects. These therapeutic effects are due to the fact that Claritin blocks histamine receptors. The effects develop very quickly (within half an hour) after taking the drug, and their duration is up to 24 hours.

The drug Claritin is not able to pass through the blood-brain barrier and bind to histamine receptors located in the central nervous system, so it does not have a sedative effect, resulting in drowsiness.

Since Claritin is an antiallergic drug, its scope of use is determined by the fight against the symptoms of this pathology.

Indications for use of the drug are the following conditions:

seasonal allergic rhinitis (hay fever);
year-round allergic rhinitis;
seasonal or year-round allergic conjunctivitis;
chronic urticaria;
skin diseases of an allergic nature (for example, dermatitis, eczema, etc.);
Quincke's edema;
allergic reaction to bites of various biological objects;
pseudo-allergic reaction associated with the consumption of histamine-releasing products (for example, tomatoes, strawberries, chocolate, coffee, cocoa, etc.).

Claritin relieves the symptoms of these allergic pathologies, such as:

sneezing;
itching;
swelling of the mucous membrane;
feeling of nasal congestion;
runny nose;
lacrimation;
bronchospasm;
burning and itching in the eyes, nose and skin;
rashes.

Both syrup and Claritin tablets are taken orally at any time, regardless of meals. The tablet or syrup should be washed down with plain, clean water.

The dosage is determined by the person’s age and concomitant pathologies. Children under 3 years old should be given Claritin in the form of syrup, and over 3 years old - in tablets or syrup, at their own discretion.

Adults and adolescents, starting from 12 years of age, take Claritin in the form of tablets at a dosage of 10 mg, once a day. A dose of 10 ml corresponds to one tablet or two measuring spoons of syrup.

Children aged 2 to 12 years should receive Claritin in an individual dosage, which depends on body weight. If the child's weight is less than 30 kg, then the dosage of Claritin is 5 mg (half a tablet) or 5 ml (1 spoon of syrup), once a day. In this case, it is better to use syrup, since the dosage of the drug will be more accurate than when breaking off half a tablet.

If the child’s body weight exceeds 30 kg, then the dosage is 10 mg (1 tablet) or 10 ml (2 tablespoons of syrup) once a day.

An overdose of the drug is possible if the dose is exceeded by more than 40 mg per day. In this case, the following symptoms develop: headache, drowsiness, rapid heartbeat.

Children weighing less than 30 kg react to an overdose of Claritin with rapid heartbeat and extrapyramidal symptoms (impaired muscle tone, slow worm-like movements of the fingers, distorted mouth, twitching of the lips, torticollis, tics, trembling, swinging movements of the limbs, etc.).

Treatment is aimed at eliminating symptoms and removing the drug from the body as quickly as possible. Removal of the drug is carried out by gastric lavage with saline solution and the use of adsorbents (for example, powdered activated carbon with water).

Ketoconazole, erythromycin and cimetidine increase the concentration of Claritin in the blood, but this does not manifest itself clinically. But this circumstance should be kept in mind so as not to get an accidental overdose.

Children can be given the drug from the age of 2 years. A child between 2 and 3 years of age should receive Claritin only in the form of syrup.

Upon reaching 3 years of age, the child can take the medicine in both syrup and tablets. That is why the syrup is called children's Claritin.

The main determining factor in the dosage of Claritin in children is body weight. It is important to remember that Claritin is taken in the appropriate dosage once a day, preferably at the same time of day.

1. Child’s body weight is more than 30 kg – take Claritin 10 mg (2 measured or teaspoons of syrup or 1 tablet);

2. Child’s body weight is less than 30 kg – Claritin take 5 mg (1 scoop or teaspoon or half a tablet).

Sometimes the dosage regimen is changed and the child is given 10 mg of Claritin every other day.

The duration of the course of treatment depends on the speed of elimination of symptoms in an acute condition, and can range from several days to 2 weeks.

When using Claritin as a prophylactic agent, you can take the drug for a long time. In some cases, pediatricians prescribe Claritin syrup to infants under 2 years of age, since the drug relieves allergic symptoms well and has virtually no side effects such as drowsiness and inhibition of central nervous system activity.

Only a smaller dosage is taken - children under 1 year of age are prescribed 1.5 ml of syrup, and children from 1 to 2 years of age are prescribed 3 ml once a day.

Pregnant women can take Claritin when the benefits of its use clearly outweigh the possible negative effects.

Experiments on animals did not reveal a negative effect of the drug on the fetus. However, such studies have not been conducted in pregnant women for obvious reasons, so it is impossible to write with scientific validity based on evidence that Claritin is definitely harmless to the human fetus.

Therefore, it is preferable to refrain from using this remedy during pregnancy.

Claritin passes into breast milk, where its concentration is the same as in a woman's blood. Therefore, if it is necessary to use the medicine during breastfeeding, you should abandon natural feeding and transfer the child to artificial formula.

Claritin has a small number of side effects that differ in adults and children. Side effects of Claritin in children include the following symptoms: headache; nervousness; lethargy.

In adults, Claritin may cause the following symptoms as side effects: headache; fatigue; drowsiness; dry mouth; nausea; gastritis; rash; baldness; cardiopalmus; tachycardia; functional liver disorders.

"Claritin": analogues (cheaper), list of synonyms

When trying to find a replacement for Claritin, you need to understand the pharmaceutical difference between such concepts as “analogue” and “synonym”. An analogue is a drug that has a similar effect to Claritin and has the same antihistamine effect on the human body. Synonyms are drugs that have an almost completely identical composition with Claritin, that is, the main component in them is loratadine. Such synonymous drugs include the following drugs in various forms of release:

"Loratadine" (tablets and syrup);
"Alerpriv" (tablets);
Clarotadine (tablets and syrup);
"Erolin" (syrup and tablets);
"Lotaren" (rectal suppositories);
"Claridol" (syrup and tablets);
"Clarifer" (tablets);
"Lomilan" (suspension, lozenges and tablets).

In all of the drugs listed above, loratadine is the main active ingredient and therefore they are all considered synonymous with a medicine such as Claritin. We will give analogues (cheap) below:

"Peritol" (syrup and tablets);
"Fexofast" (tablets);
"Ketotifen" (tablets and syrup);
"Semprex" (capsules);
"Diazolin" (dragées and tablets);
"Desloratadine Canon" (tablets);
"Ketotifen Sopharma" (tablets and syrup);
"Kestin" (syrup and tablets);
"Rapido" (capsules);
"Fexadin" (tablets);
"Ketotifen-Ros" (tablets);
Dramamine (tablets);
"Telfast" (tablets);
"Allerfex" (tablets);
"Diacin" (tablets);
"Dimedroquine" (tablets).

Due to its pleasant taste, this syrup is the best analogue of Claritin for children, since they take it more readily than regular tablets. The antihistamine effect from taking 1 dose of syrup and one tablet (10 mg) lasts 24 hours. The average cost of a package (20 tablets) is 160 rubles, syrup in a 60 ml bottle costs about 110 rubles.

Claritin for children (syrup) - instructions for use

Claritin is also effective in the development of immediate allergic reactions, such as angioedema, insect bites and others, which makes it possible to use it as an emergency remedy.

Many people suffering from allergies highly appreciate the properties of Claritin, use it successfully and leave positive reviews.

However, the medicine is quite expensive, which is a disadvantage.

Among the huge number of positive reviews about Claritin, there are also a small number of negative ones. The negative opinion about the drug is due to the fact that it turned out to be ineffective in eliminating the existing symptoms.

Unfortunately, people often take the drug without a doctor’s prescription, considering a certain set of symptoms to be an allergic reaction. Often the symptoms are not allergic, and Claritin does not help, but the person considers the product expensive and ineffective.

It should be fairly noted that Claritin really does not help a small number of people with allergic reactions, which is due to the individual characteristics of the body, and in this situation it is necessary to change the drug.

Many parents used Claritin even in infants, reducing the dose by 4 times, according to the pediatrician's instructions. The drug perfectly relieved allergic rashes, runny noses and other symptoms in children, without disturbing the functioning of the gastrointestinal tract and respiratory system.

Pediatricians often prescribe this drug to relieve bronchospasm in frequently ill children, which helps normalize the child’s breathing. That is why, in most cases, reviews of Claritin for children are positive.

Negative reviews were left by parents whose children the drug did not help eliminate painful symptoms. In this situation, an additional factor of irritation is the rather high price of the medicine, which causes a strong emotional connotation of the negative review about Claritin left by parents.

Tablets 7 pieces 165 – 210 rubles.
Tablets 10 pieces 230 – 245 rubles.
Tablets 30 pieces 595 – 665 rubles.
Syrup 60 ml 260 – 290 rubles.
Syrup 120 ml 365 – 425 rubles.

Before use, you should consult a specialist.

Negative reviews about this drug are, indeed, extremely rare and most often they are caused by the rather high price of the drug (in comparison with its cheaper analogues). Buyers for whom the price of this drug was initially very high and after purchasing did not receive the expected effect (individual rejection of the drug, features of allergic reactions, unauthorized use without a doctor’s prescription, when external allergy symptoms were caused by other diseases) speak out especially emotionally about Claritin. .

Their main active ingredient is desloratadine. The drug is available both in syrup and tablet form. Indications for its use are:

urticaria (relieves itching and skin rashes);
allergic rhinitis (year-round and seasonal).

The effect of 1 tablet (5 mg) lasts 24 hours; accordingly, patients over 12 years of age are prescribed 1 tablet. per day, regardless of food intake. The average cost of a package of Erius (10 tablets) is 560 rubles.

If we compare Claritin and Erius, it is worth noting that both of these drugs belong to the third generation antihistamines. Therefore, they have almost the same therapeutic effects. Also, such a common side effect of antihistamines as drowsiness, both Claritin and Erius are minimized.

Due to its pleasant taste, this syrup is the best analogue of Claritin for children, since they take it more readily than regular tablets. The antihistamine effect from taking 1 dose of syrup and one tablet (10 mg) lasts 24 hours. The average cost of a package (20 tablets) is 160 rubles, syrup in a 60 ml bottle costs about 110 rubles.

If we compare Cetrin with Claritin, it is worth noting that they belong to different generations of antihistamines. Cetrin is a representative of the second generation and its effect is weaker than that of Claritin, while it has many more possible side effects. When comparing these two drugs, your preference can be given to Claritin, while Cetrin retains one main advantage - price.

It is indeed much cheaper and, accordingly, is a more accessible analogue of Claritin for the majority of the population.

General information

The pharmaceutical industry offers a wide range of drugs to manage allergy symptoms, including antihistamines. They are so called because they block the sensitivity of receptors to histamine produced in mast cells. These cells are located in all organs and tissues and contain many biologically active substances, including inflammatory mediators. Among them, the main one is histamine, which exhibits its destructive effect only under certain conditions, for example, when the body becomes hypersensitive to any substances (allergens). Any biologically active substance has a point of application in the body, so-called receptors, located in different organs and tissues. When histamine binds to its receptors, a number of pathological changes occur, for example, swelling of the mucous membrane, production of secretions in large quantities, itching of the skin, rash, bronchospasm, etc.

In other words, it is histamine that causes the appearance of all the main symptoms of allergies. To stop it, it is necessary to close the sensitive receptors and block access to them. For this purpose, many decades ago, special preparations were developed and put into practice.

Antihistamines have been and remain today the number one medicine in the treatment of allergic diseases, because they act directly on the mechanism of development of the pathological reaction.

New drugs - third generation

Medicines of this group began to be produced in the 21st century; they are distinguished by improvements in the formula of existing second-generation drugs in order to ensure greater bioavailability to tissues, reduce the load on the liver, and reduce side effects. For example, instead of loratadine, its active metabolite desloratadine is used as the active substance, and instead of cetirizine, levocetirizine is used.

The third generation includes the following drugs:

Telfast, Gifast (fexofenadine hydrochloride);
Erius, Dezal (desloratadine);
Xyzal, Zenaro (levocetirizine);
Kestin (ebastine);
Norastemizole.

New antihistamines have a long-lasting therapeutic effect, do not dry out the mucous membranes, can be taken once a day, do not have a sedative effect, and therefore are approved for representatives of various professions.

The disadvantage is the lack of a dosage form for intramuscular administration, which does not allow their use to relieve acute allergic reactions. The main indications for their use are chronic diseases of an allergic nature - bronchial asthma, recurrent urticaria, seasonal or year-round allergic rhinitis, atopic dermatitis, food allergies.

Allergic diseases are extremely common throughout the world among people of all ages and represent a serious problem, the effective solution of which lies in the radical elimination of the culprit allergen. However, this is not always possible as quickly as we would like. Antihistamines are widely used to relieve unpleasant symptoms. Which of them are the best choice for patients – let’s try to figure it out together.

We recommend reading: Salbutamol: instructions for use for adults and children, composition and side effects

Old drugs

Today, three generations of antihistamine drugs are known. Each subsequent one has an improved formula, fewer side effects and better tolerability. The first generation includes the following drugs (trade names and active substance):

Suprastin (chloropyramine);
Fenkarol (hifenadine hydrochloride);
Diazolin (mebhydrolin);
Tavegil (clemastine hydrofumarate).

You may also be interested in: Choosing the best remedy for treating a runny nose

Old generation products have their own characteristics of action:

they briefly close histamine receptors, forming not very strong bonds with them, therefore they have a short-term effect (about 6-8 hours) and should be taken 3 times a day;
can be used for no more than 10 days in a row, otherwise they either become ineffective or may cause paradoxical reactions;
have a significant drawback - a side effect in the form of drowsiness and lethargy, which limits their use among workers in certain professions that require increased attention;
have a drying effect on the mucous membrane of the respiratory tract, which can be used for therapeutic purposes (for example, for allergic rhinitis), but is not always desirable (for example, for bronchial asthma);
are produced not only in tablets, but also in ampoules for injection, which is undoubtedly an advantage.

Currently, these drugs are prescribed less frequently, but they still occupy their niche in clinical practice.

The main indication for prescribing first-generation antihistamines is acute allergic reactions (urticaria, Quincke's edema), in which it is necessary to quickly block histamine receptors by intramuscular administration of the drug.

Most older antihistamines can be used from the first year of life. These properties are an undoubted advantage of Suprastin over Claritin and other similar drugs.

Common features between Tavegil and Suprastin

To relieve the first manifestations of an allergic reaction, drugs are often used - first generation antihistamines, their group includes Suprastin and Tavegil.

The medications are identical in their action, and many years of experience in their use shows good results from the use of these medications.

Both drugs are used when an allergic reaction leads to itchy skin, conjunctivitis, seasonal rhinitis, and urticaria.

Medicines are effective in treating allergies that develop from insect bites. Medicines in ampoules quickly reduce the manifestations of Quincke's edema.

The general properties of Tavegil and Suprastin also include:

The same time for the development of the therapeutic effect. Allergy symptoms begin to decrease after 30 minutes, and after two hours the maximum activity of the drugs appears.
Duration of antiallergic effect on the body. The instructions for Tavegil indicate that the effect of this drug lasts up to 12 hours; when taking Suprastin, the therapeutic effect can last up to 8 hours. Despite the difference in the time of action, both drugs are recommended for adult patients to be given three times a day.
High probability of liver tissue damage. The hepatotoxic effect of first-generation antihistamines mainly manifests itself when treatment periods are not followed.
A ban on the use of these drugs to treat pregnant women.

There are certain differences between the two drugs, so the attending physician must decide whether Tavegil or Suprastin is better.

Claritin and Zodak which is better akwa21.ru

Claritin and its analogues: Suprastin, Loratadine, Zodak, Loridin

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Claritin is a group of new generation antihistamines. According to many allergists, this remedy is more effective than its predecessors, after administration, which causes side effects. However, in practice, most often people use Claritin analogues rather than the drug itself.

Indications for use

The drug "Claritin" is a medicine classified as an antiexudative, antihistamine. Its effect is based on the ability to block histamine H1 receptors. This action gives the drug excellent antipruritic, antiallergic, and anti-edematous properties.

The big advantage of the medicine is that it does not affect the functioning of the nervous system. This remedy does not depress her.

The medicine "Claritin" has the following indications for use:

burning and itching in the nasal cavity, eyes;
conjunctivitis of various origins;
rhinitis, rhinorrhea, sinusitis of allergic origin;
swelling of tissues;
food allergies;
hives;
drug allergies;
skin diseases – psoriasis, eczema, contact dermatosis;
bronchial spasms;
Quincke's edema;
allergic reaction to insects.

Claritin: instructions for use. Indications

Claritin is recommended for use to eliminate the symptoms of allergic diseases:

Rhinitis is a disease that occurs due to interaction with respiratory allergens, for example, pollen, dust, wool. It is accompanied by rhinorrhea, nasal congestion and itching, and sneezing.

Conjunctivitis is an inflammatory process in the mucous membrane of the eyes that develops due to interaction with allergens, for example, cosmetics, or against the background of allergic rhinitis. It manifests itself as redness, irritation, itching and burning of the conjunctiva.

Release forms

Claritin allergy medicine is available in two forms.

The tablets are oval in shape. One side of the pill contains a score and the number “10”. It is also located here. The other side is smooth. White tablet.

Syrup is a sweet, thick liquid. It is transparent, without the inclusion of solid particles. The color of the syrup is somewhat yellowish. The liquid is produced in dark glass bottles. The manufacturer produces the product in containers from 60 to 120 ml.

Claritin during pregnancy and lactation

Studies of Claritin during gestation were conducted only on lesser brothers (animals). During testing, no teratogenic effect on the fetus was detected.

Due to the fact that the drug has not been tested on pregnant women, there is no direct indication for its use, although in critical cases Claritin can be prescribed.

The recommended dose is selected by the doctor ; most likely, a children's dosage will be suggested - 5 ml of syrup or half a Claritin tablet.

It is better to combine the use of Claritin tablets during lactation with a temporary transfer of the child to industrially produced milk or dairy-free formulas.

Medicine dosage

It is recommended to consult a doctor before using Claritin. The use of this drug, according to the instructions, is as follows:

Children over 12 years of age and adults should take 1 tablet (10 mg) or 2 teaspoons of syrup (10 ml) once a day.
Patients diagnosed with renal failure or liver dysfunction should take the medicine in the above dosages, but every other day.
Children 2-12 years old weighing less than 30 kg take 0.5 tablets (5 mg) or 1 teaspoon (5 ml) daily.
Children 2-12 years old, whose weight exceeds 30 kg, take 1 tablet or 2 teaspoons of syrup once a day.

How does Claritin work?

According to the instructions, Claritin has antiallergic and antipruritic properties. 30 minutes after taking the medicine, a decrease in allergy symptoms is observed, and the effect of the drug persists throughout the day. The selective property of the drug can significantly eliminate the effect of loratadine on the central nervous system.

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Claritin, as an analogue of Tavegil with Suprastin

The second generation antihistamine, Claritin, has a therapeutic effect similar to Suprastin and Tavegil. The main active ingredient of this medication is loratadine.

The drug is produced in Belgium and America. Claritin is effective in treating:

Allergorinitis (Seasonal and year-round);
Hay fever;
Conjunctivitis;
Chronic urticaria (idiopathic).

Claritin is often prescribed as an adjunct in the treatment of patients with bronchial asthma. The drug effectively eliminates symptoms resulting from insect bites.

The medicine is available in two forms - in the form of tablets and in the form of syrup. Children from two years of age are prescribed syrup.

Compared to clemastine and chloropyramine, loratadine has several differences:

Prolonged action. The antihistamine effect during treatment with Claritin lasts for 24 hours. Therefore, the medicine can be taken only once a day;
No hypnotic effect;
Possibility of long-term use. For some diseases, Claritin is prescribed for two to three months or more;
Lowest likelihood of side effects.

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Claritin is contraindicated in only a few cases - women during lactation, children under two years of age, with individual intolerance to the components of the medication.

During pregnancy, the drug can be used after prescription by a doctor.

Suprastin or Claritin: which to choose?

People suffering from allergic reactions are constantly looking for the best way to get rid of this disease.
The most popular drugs are Suprastin and Claritin. Despite the fact that the purpose of the medications is the same, there are a number of significant differences.

Suprastin and its effect against allergies

Allergies are one of the most common diseases among people of different age groups. There are a huge number of causes for this disease, and many allergists recommend the antihistamine Suprastin to eliminate the allergic reaction.

It contains chloropyramine hydrochloride, which has a calming, antipruritic and sedative effect. The medication perfectly soothes the itching of human skin and has a positive effect on the body as a whole.

The antihistamine is dispensed in tablet form and as injections. The advantage of this drug is that any form of it can be used as a treatment for allergies, even in infancy.

Directions for use: The tablet form is taken with meals, the total dosage of which should not exceed 4 times. The use of antihistamine should be strictly according to the instructions, as well as as prescribed by the attending physician.

Injections are used only in severe situations, most often with urticaria, allergic shock or suffocation.

It is important to know that the medication carries certain contraindications and side effects, so antihistamine therapy should be carried out only under the strict guidance of a specialist - an allergist.

Also, antihistamine is not recommended for use during pregnancy, in the presence of kidney diseases, or during lactation.

Claritin - a new generation antihistamine

Most allergy sufferers choose this type of drug due to its effectiveness and duration of action.

Claritin has taken a high position among antihistamines, and this is not surprising, because the indication for use is:

skin rashes;
hives;
various allergic reactions;
seasonal nasal congestion – allergic rhinitis (sneezing, swelling of the mucous membrane, itching in the nose, itching and watery eyes).

The antihistamine is available in the form of tablets (10 mg), as well as in the form of syrup (60 ml or 120 ml), which is prescribed in childhood. The action of the drug is aimed at antipruritic, antihistamine and antiallergic effects.

Directions for use: 10 mg tablets are taken orally every day, and for people suffering from liver or kidney diseases, the drug is prescribed every other day.

The syrup is usually prescribed to children, the dosage of which is calculated taking into account the child’s weight category.

The use of the drug must be strictly according to the prescription of an allergist, who is able to prescribe the exact dosage and correct treatment for the disease. After all, the medication has a lot of contraindications and side effects.

What are the differences between these drugs?

Despite the fact that the mechanisms of action of these drugs are similar, there are some differences between them. Antihistamines are divided into subclasses, namely:

first generation drugs – Suprastin and others;
antihistamines of the second and third (new) generation - Claritin and others.

Each product has its own antihistamine effect, has a special improved formula, a special number of side effects and individual tolerance.

Suprastin and Claritin have a number of differences, which include:

Efficacy of the drug. Many allergists believe that improved antihistamines are much more effective than first-generation drugs, namely, they are highly effective and have a long duration of action. But with acute signs of response from the body’s immune system, Claritin is less effective than Suprastin.
Side effects. Claritin is a more gentle remedy, therefore it is not capable of causing side effects from the digestive and central nervous systems, unlike Suprastin, which works selectively and therefore has a significant number of side effects. For example, Claritin is not able to provoke drowsiness, while Suprastin, on the contrary, leads to passivity and lethargy. Also, the old generation drug irritates the mucous membrane of the eyes, thereby provoking the development of infectious diseases, when Claritin in no way harms the mucous membrane, therefore, the likelihood of a bacterial infection is reduced to zero.
Directions for use and dosage. The daily dosage of Suprastin is considered to be the use of 3-4 tablets, for children - depending on the age category. Claritin is dosed based on the child's weight, and adults are prescribed 1 tablet - 1 time per day.

In what cases is the use of antihistamines more effective?

Each medication is perfect in its own way, but does not always help cope with the problem of an allergic reaction. Suprastin is used in the following cases:

itching of human skin, allergic manifestations in the form of rashes, urticaria;
skin allergy due to foreign protein entering the body, in other words – serum sickness;
anaphylactic reactions;
for allergic reactions of the ear, nose and throat organs - Suprastin helps to cope with swelling of the ENT organs, allergic runny nose and nasal congestion;
in combination with Analgin and No-shpa, Suprastin is prescribed to reduce temperature;
For children prone to allergies, the pediatrician may prescribe the drug before vaccinations.

The range of uses of Claritin is significantly lower:

According to many allergists, Claritin is not very effective for acute and idiopathic chronic urticaria; in such cases, Suprastin in the form of injections helps well.

The opinions of experts differ; some say that Suprastin is more effective in the fight against allergies, while others, on the contrary, argue that older generation drugs are no longer productive.

Many doctors advise using Suprastin, despite its age, because the old generation antihistamine will always remain in the forefront for allergic conditions. It copes well with moderate and mild allergy symptoms, and is also available in all pharmacies, including financial issues.

Suprastin is also prescribed for the treatment of joint disease in childhood, for example, infectious-allergic arthritis. As a rule, pain and limitation of movements disappear on the fifth day of taking the drug.

But people whose work involves driving a car should not take the drug, because the antihistamine can cause drowsiness and loss of concentration.

There are many experts who consider Claritin a rated drug.

After all, the medication is not addictive, is taken only once a day, does not cause drowsiness or loss of concentration, does not have a sedative effect, and is also available without a doctor’s prescription.

But there are also some nuances, which include individual intolerance to the components of the drug, as well as the high price of the antihistamine.

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Source: https://allergia.life/lekarstva/ot-allergii/suprastin-ili-klaritin.html

What to choose - Tavegil or Suprastin

Antiallergic treatment should be selected only by a doctor. A qualified allergist takes into account not only the age of the patients, but also the nature of pathological changes, their severity, and the functioning of all internal organs.

Both Suprastin and Tavegil are prescribed only for a short course - the medicine cannot be used for more than one week.

Therefore, their use is justified only in the case of an acutely developing allergic reaction; in the case of a prolonged course, it is necessary to either immediately prescribe drugs intended for long-term use, or replace first-generation antihistamines with safer ones after 5-7 days of taking them.

For adult patients with allergic diseases that occur with pronounced symptoms of swelling, itching, and hyperemia of the skin, doctors prefer to prescribe Suprastin.

If the allergy manifests itself with smoothed symptoms, then it is better to choose Tavegil, since it acts more mildly, causes side effects less often and does not lead to drowsiness.

The choice of drugs for children is based on the same principles. If the allergy does not cause any particular discomfort and does not increase, then preference should be given to Tavegil.

In case of a rapidly growing allergic reaction, the best therapeutic effect is observed when taking Suprastin; the main thing is not to make a mistake with the dosage.

There is an opinion that treatment of boys with Suprastin at an early age can cause sexual dysfunction in the future. This opinion is not substantiated or supported by anything, but without a doctor’s prescription, you should not get carried away with first-generation antihistamines.

People who have experienced an allergic reaction at least once in their lives understand perfectly well how much discomfort an allergy can cause if it is not treated promptly.

Claritin is a drug in tablets and syrup for allergies, produced by the famous company Bayer. Depending on the form, it is approved for use in children aged 2 and 12 years. The cost of the medicine is from 190 to 650 rubles.

Unfortunately, the drug is not available to all pharmacies and the question of cheaper Claritin analogues is relevant. When choosing, pay attention to the composition, duration of the therapeutic effect and frequency of administration, side effects, read the instruction insert.

Characteristics of drugs

Pharmacological companies offer a large selection of medicines. Before choosing a medication, you should study the attached instructions.

Claritin

An antihistamine that contains loratadine. Available in tablets and syrup. Characterized by antipruritic and antiallergic effects.

The mechanism of action of the drug is based on selective blocking of peripheral H1-histamine receptors. The active component begins to act after 30 minutes. The effect lasts 20-24 hours. Does not affect the nervous system and does not exhibit anticholinergic and sedative effects.

The medicine is prescribed for:

year-round or seasonal allergic rhinitis;
conjunctivitis;
chronic idiopathic urticaria;
allergic manifestations on the skin.

The instructions indicate several contraindications in the form of:

increased susceptibility to the components of the drug;
children under 2 years of age;
lactation period.

While taking tablets and syrup, side symptoms may appear. This process is accompanied by:

headaches;
increased fatigue;
dry mouth;
drowsiness;
disruption of the gastrointestinal tract.

A headache may occur while taking Claritin.

In rare cases, anaphylactic shock, tachycardia, and impaired liver and heart function are diagnosed. Children experience headache, nervousness and drowsiness.

Suprastin

The active ingredient is chloropyramine hydrochloride. Available in tablets and solution. It has antiallergic and antihistamine properties.

The active substance is considered an analogue of tripelenamine and belongs to the category of first generation antihistamines, therefore it exhibits a sedative effect.

The mechanism of action is based on the ability to block histamine type H1 receptors.

The drug is prescribed for:

urticaria and other allergic manifestations;
hay fever;
serum sickness;
allergic rhinopathy;
dermographism.

Used as an adjuvant for angioedema and anaphylactic shock.

Included in complex therapy for swelling of the mucous membranes of the middle ear and nose during ARVI.

It has several contraindications such as:

acute asthma attacks;
gastric ulcer;
angle-closure glaucoma;
treatment with inhibitors;
arrhythmias;
acute myocardial infarction;
prostate hyperplasia;
urinary retention;
increased susceptibility to the components of the drug.

During treatment with the drug, side symptoms may appear. This process is characterized by:

increased fatigue, sedation, dizziness, convulsions;
tremor, headaches, encephalopathy, decreased clarity of vision;
arrhythmia, tachycardia, arterial hypotension;
pain in the epigastric region, dry mouth, diarrhea, nausea and vomiting;
anemia;
glaucoma;
dysuria.

Suprastin has a contraindication in the form of acute asthma attacks.

In rare cases, Quincke's edema, myopathy, and reaction to sunlight are diagnosed.

Claritin or Cetrin - which is better for allergies

Manufacturer: Dr. Reddy S, India

Active ingredient: cetirizine

Synonyms: Cetirizine, Zodac, Zirtec, Parlazin, Solonex

Cetrin is an antiallergic drug in the form of tablets, belonging to the second generation. The therapeutic effect of this Claritin analogue begins within 20 minutes and lasts up to a day. When used in recommended doses, the drug does not have a sedative effect, but slight drowsiness is possible.

Advantages of Cetrin: can be used in children from 6 years of age, quick effect within 20 minutes, reasonable cost, ease of use - only one tablet per day.

The manufacturer produces Cetrin in packages of 20 and 30 tablets. The first form is convenient for a short course of treatment, rare exacerbations of allergies or a reaction that appears for the first time. The larger packaging is suitable for chronically ill patients or a family medicine cabinet if there are several allergy sufferers in the house. If you compare Claritin and Cetrin, the drugs are similar. Analogs have the same principle of action, the therapeutic effect appears within an hour. Both analogues are taken once a day. If one medicine does not help, you can replace it with another.

Claritin or Zodak – which is better for allergies?

Manufacturer: Zentiva, Germany or Czech Republic

Release form: tablets, drops

Active ingredient: cetirizine

Synonyms: Cetirizine, Cetrin, Zyrtec

Zodak is a drug that can replace Claritin if it is ineffective. The analogue contains a different main substance, from the second generation. Used in the form of drops and tablets.

Zodak and Claritin are similar products, have similar indications and restrictions for use. The advantage is the absence of drowsiness in patients.

Analogues of the product: what does the choice depend on?

The drug has many analogues. Their choice depends on many factors.

severity of allergy;
duration of illness;
forms of the disease;
effectiveness of tablets.

Doctors assure that there is no optimal, ideal pill for all allergic forms and for all patients. Before purchasing any medicine, consultation with a doctor is required. Otherwise, negative consequences cannot be avoided.

Here is a list of analogues of the product, which, thanks to the development of the pharmaceutical industry, is constantly expanding:

Suprastin.
Loratadine.
Clargothyl.
Kestin.
Zodak.
Loridin.
Lomilan.

Most patients wonder what is more effective: Claritin or Suprastin.

The latter is most effective when it comes to an acute allergic reaction.

If a patient, for example, has hives, the temperature rises sharply, and the entire skin is covered with a rash, then the best solution is to take Suprastin.

It will very quickly relieve the primary symptoms.

Claritin is optimal if the patient suffers from chronic urticaria. In this case, the symptoms do not manifest themselves clearly, rare and pale rashes are observed.

Loratadine and Zodak

Despite all its efficiency and effectiveness, Loratadine has a lot of side effects. Adult patients often complain of migraine, drowsiness and tachycardia after taking tablets.

Zodak is highly effective against urticaria and is quickly eliminated from the body into the external environment.

Zodak and Claritin are drugs of the same generation. The basis of the first is cytisine, the second is loratadine.

Zodak has a calming effect on the patient. It is eliminated from the body in 7 hours, and Claritin is 3 times slower.

Many patients using Zodak say that they have difficulty urinating, a feeling of dry mouth, and nervous excitability. Some pharmacists believe that Claritin is more effective than Zodak for skin rashes. This has not yet been proven by scientists.

Medicine Loridin

The next analogue has a wide spectrum of action. The patient takes Loridin if he is concerned about:

rhinitis;
hives;
hay fever;
Quincke's edema.

At the same time, the remedy is also effective for allergies to bites, lesions and serum sickness. Doctors prescribe it as a complex therapy:

with dermatitis, which is accompanied by itching;
skin allergies;
for eczema, which occurs acutely or chronically;
for rhinitis as a prophylaxis.

The drug is contraindicated in pregnant women, breastfeeding women, and those with renal failure.